A ROS-Responsive Dual-Targeting Drug Nanocarrier Serving as a GSI Synergist and Ferroptosis Sensitizer for T-Cell Acute Lymphoblastic Leukemia., PMID:40448620
Co-inhibition of Notch1 and ChK1 triggers genomic instability and melanoma cell death increasing the lifespan of mice bearing melanoma brain metastasis., PMID:40437523
Mutation Mapping of PD-L1 Expression in Advanced Non-small Cell Lung Cancer: A Real-world Retrospective Cohort Study., PMID:40289990
Treatment outcomes of BTK inhibitors and venetoclax with or without anti-CD20 monoclonal antibody in relapsed or refractory mantle cell lymphoma., PMID:40278919
NOTCH1 Mutation and Survival Analysis of Tislelizumab in Advanced or Metastatic Esophageal Squamous Cell Carcinoma: A Biomarker Analysis From the Randomized, Phase III, RATIONALE-302 Trial., PMID:40179324
Evaluation of Notch1 and CD10 Expressions in Colorectal Carcinoma and Their Relationship with Prognosis., PMID:40060224
Clinical Outcomes With Notch Inhibitors in Notch-Activated Recurrent/Metastatic Adenoid Cystic Carcinoma., PMID:40025676
Synapsin III promotes neuronal-like transdifferentiation of glioblastoma stem cells by disrupting JAG1-Notch1 interaction., PMID:39994412
The interplay of cancer-associated fibroblasts and apoptotic cancer cells suppresses lung cancer cell growth through WISP-1-integrin ανβ3-STAT1 signaling pathway., PMID:39966869
The potential role of RhoA/ROCK-inhibition on locomotor recovery after spinal cord injury: a systematic review of in-vivo studies., PMID:39956860
Melatonin ameliorates astrogliosis and microgliosis in a cuprizone demyelinating mouse model., PMID:39926210
Association of Specific Gene Mutations with Immunoglobulin Heavy-Chain Variable Region and Chromosomal Alterations in Chronic Lymphocytic Leukemia Patients in India., PMID:39873992
NOTCH1 Mutations Are Associated With Therapy-Resistance in Patients With B-Cell Lymphoma Treated With CD20xCD3 Bispecific Antibodies., PMID:39865309
Sirt6 regulates the Notch signaling pathway and mediates autophagy and regulates podocyte damage in diabetic nephropathy., PMID:39754634
Targeted delivery of DAPT using dual antibody functionalized solid lipid nanoparticles for enhanced anti-tumour activity against triple negative breast cancer., PMID:39746584
Retinal Müller Cell-Released Exosomal MiR-92a-3p Delivers Interleukin-17A Signal by Targeting Notch-1 to Promote Diabetic Retinopathy., PMID:39745681
Prognostic and predictive impact of NOTCH1 mutation in chronic lymphocytic leukemia: a systematic review., PMID:39727347
USP18-mediated protein stabilization of NOTCH1 is associated with altered Th17/Treg cell ratios and B cell-mediated autoantibody secretion in Sjögren syndrome., PMID:39672989
Bevacizumab increases cisplatin efficacy by inhibiting epithelial-mesenchymal transition via ALDH1 in cervical carcinoma., PMID:39662269
The Jag2/Notch1 signaling axis promotes sebaceous gland differentiation and controls progenitor proliferation., PMID:39585329
Modulation of Notch signaling pathway in activated hepatic stellate cells does not ameliorate the outcome of liver fibrosis in carbon tetrachloride and DDC-feeding models., PMID:39529885
Notch1 blockade by a novel, selective anti-Notch1 neutralizing antibody improves immunotherapy efficacy in melanoma by promoting an inflamed TME., PMID:39491031
NOTCH1 drives tumor plasticity and metastasis in hepatocellular carcinoma., PMID:39484457
VASN promotes the aggressive phenotype in ARID1A-deficient lung adenocarcinoma., PMID:39472811
Dynamic roles of neutrophil extracellular traps in cancer cell adhesion and activation of Notch 1-mediated epithelial-to-mesenchymal transition in EGFR-driven lung cancer cells., PMID:39430758
Identification of DLK1, a Notch ligand, as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma., PMID:39416174
Astrocytic DLL4-NOTCH1 signaling pathway promotes neuroinflammation via the IL-6-STAT3 axis., PMID:39390606
Advances in the understanding of molecular genetics and therapy of Richter transformation in chronic lymphocytic leukemia., PMID:39219481
Mechanistic Insights and Therapeutic Strategies in Osteoporosis: A Comprehensive Review., PMID:39200100
NOTCH1- and CD117-Positive Stem Cells in Human Endometriosis and Adenomyosis Lesions., PMID:39125516
Brain ischemia causes systemic Notch1 activity in endothelial cells to drive atherosclerosis., PMID:39079536
Inhibition of Notch4 Using Novel Neutralizing Antibodies Reduces Tumor Growth in Murine Cancer Models by Targeting the Tumor Endothelium., PMID:38984877
Another Notch in the Belt of Rheumatoid Arthritis., PMID:38961731
Molecular hydrogen promotes retinal vascular regeneration and attenuates neovascularization and neuroglial dysfunction in oxygen-induced retinopathy mice., PMID:38915069
Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages., PMID:38636522
Therapeutic Advances and Challenges for the Management of HPV-Associated Oropharyngeal Cancer., PMID:38612819
Gamma-delta T-cell acute lymphoblastic lymphoma/leukemia: a report of a rare entity., PMID:38528212
Efficient Escorting Strategy for Aggregation-Prone Notch EGF Repeats with Sparcl1., PMID:38474544
Mutational, immune microenvironment, and clinicopathological profiles of diffuse large B-cell lymphoma and follicular lymphoma with BCL6 rearrangement., PMID:38462571
Epithelium-derived kallistatin promotes CD4+ T-cell chemotaxis to TH2-type inflammation in chronic rhinosinusitis., PMID:38403085
Notch-1/2 receptors and Jagged-1 ligand, but not HERP-1 transcription factor, are immunohistochemically expressed in the epithelial lining of periapical cysts., PMID:38314334
Gamma protocadherins in vascular endothelial cells inhibit Klf2/4 to promote atherosclerosis., PMID:38293157
Activation of Notch-1 signaling pathway in macrophages to secrete PD-L1 and regulate cytotoxicity of CAR-T cells in diffuse large B-cell lymphoma., PMID:38261741
Anti-NOTCH1 therapy with OMP-52 M51 inhibits salivary adenoid cystic carcinoma by depressing epithelial-mesenchymal transition (EMT) process and inducing ferroptosis., PMID:38253083
Chronic Lymphocytic Leukemia IGHV Somatic Hypermutation Detection by Targeted Capture Next-Generation Sequencing., PMID:38175592
Notch signaling in thyrocytes is essential for adult thyroid function and mammalian homeostasis., PMID:38123718
The Notch1 signaling pathway directly modulates the human RANKL-induced osteoclastogenesis., PMID:38040752
Notch ligands are biomarkers of anti-TNF response in RA patients., PMID:37796367
Targeting NOTCH1 in combination with antimetabolite drugs prolongs life span in relapsed pediatric and adult T-acute lymphoblastic leukemia xenografts., PMID:37667380
The beneficial effects of l-carnitine and infliximab in methotrexate-induced hepatotoxicity: Emphasis on Notch1/Hes-1 signaling., PMID:37625018
For research use only. Not for human or drug use.
