Catalog No.
RVV08607
Expression system
Mammalian Cells
Species reactivity
Hepatitis C virus genotype 1a (isolate H77) (HCV)
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
NS1, gp68, gp70, Envelope glycoprotein E2, Genome polyprotein
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P27958-2
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
MAb24
Escape of Hepatitis C Virus from Epitope I Neutralization Increases Sensitivity of Other Neutralization Epitopes. PMID: 29467319
Expression of stratified squamous epithelia-type cytokeratin by canine mammary epithelial cells during tumorigenesis: type I (acidic) 57 kilodalton cytokeratin could be a molecular marker for malignant transformation of mammary epithelial cells. PMID: 7515697
Humanized β2 Integrin-Expressing Hoxb8 Cells Serve as Model to Study Integrin Activation. PMID: 35563841
A humanized β2 integrin knockin mouse reveals localized intra- and extravascular neutrophil integrin activation in vivo. PMID: 35649374
A small-molecule antagonist of LFA-1 blocks a conformational change important for LFA-1 function. PMID: 11493627
Roles of Fc Domain and Exudation in L2 Antibody-Mediated Protection against Human Papillomavirus. PMID: 29743371
Leukocyte integrin activation mediates transient neutropenia after G-CSF administration. PMID: 21844566
Expression of cystic fibrosis transmembrane conductance regulator in the human distal lung. PMID: 18045644
Expression, activation, and function of integrin alphaMbeta2 (Mac-1) on neutrophil-derived microparticles. PMID: 18509085
Frontline Science: A flexible kink in the transmembrane domain impairs β2 integrin extension and cell arrest from rolling. PMID: 31475386
Cytohesin-1 regulates human blood neutrophil adhesion to endothelial cells through β2 integrin activation. PMID: 21511340
The differential role of CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in the adherence, migration and podosome formation of human macrophages and dendritic cells under inflammatory conditions. PMID: 32365067
Up-regulation and activation of eosinophil integrins in blood and airway after segmental lung antigen challenge. PMID: 18490765
Variable expression of a surface determinant during proliferation of Candida albicans. PMID: 3276622
Affinity-purification of a TMV-specific recombinant full-size antibody from a transgenic tobacco suspension culture. PMID: 10410966
Role of endothelial MCP-1 in monocyte adhesion to inflamed human endothelium under physiological flow. PMID: 12388329
L-selectin (CD62L) cross-linking signals neutrophil adhesive functions via the Mac-1 (CD11b/CD18) beta 2-integrin. PMID: 7543524
Monoclonal Antibodies Directed toward the Hepatitis C Virus Glycoprotein E2 Detect Antigenic Differences Modulated by the N-Terminal Hypervariable Region 1 (HVR1), HVR2, and Intergenotypic Variable Region. PMID: 26378182
Characterization of activated lymphocyte-tumor cell adhesion. PMID: 10857858
The human S100 protein MRP-14 is a novel activator of the beta 2 integrin Mac-1 on neutrophils. PMID: 9570563
Targeted expression of redesigned and codon optimised synthetic gene leads to recrystallisation inhibition and reduced electrolyte leakage in spring wheat at sub-zero temperatures. PMID: 16847628
Evidence for the involvement of phosphatidylinositol 3-kinase in fMLP-stimulated neutrophil adhesion to ICAM-1-transfected cells. PMID: 11392472
Rice cell culture as an alternative production system for functional diagnostic and therapeutic antibodies. PMID: 10767987
A high endothelial cell-derived chemokine induces rapid, efficient, and subset-selective arrest of rolling T lymphocytes on a reconstituted endothelial substrate. PMID: 9834123
Antidisialoganglioside/granulocyte macrophage-colony-stimulating factor fusion protein facilitates neutrophil antibody-dependent cellular cytotoxicity and depends on FcgammaRII (CD32) and Mac-1 (CD11b/CD18) for enhanced effector cell adhesion and azurophil granule exocytosis. PMID: 12010822
Soy isoflavones attenuate human monocyte adhesion to endothelial cell-specific CD54 by inhibiting monocyte CD11a. PMID: 16920859
Identification of a novel monocyte cell surface molecule involved in the generation of antigen-induced proliferative responses. PMID: 3265389
Sequential changes of hepatitis C virus antibody profiles during treatment of chronic hepatitis C of genotype 1b: pretreatment antibody response to E2/NS1 correlated sustained response., PMID:15188075
[Significance of polypeptide antigen of HCVE2/NS1 relative conservation region in detection of anti-HCV]., PMID:12759957
Expression and purification of E2/NS1 protein of hepatitis C virus and detection of anti-E2/NS1 antibodies in chronic liver disease patients., PMID:12595764
Identification of human hepatocyte protein(s), which binds specifically to the recombinant envelope-2/non-structural-1 protein of hepatitis C virus., PMID:12191777
Antibody response to E2 glycoprotein induced in mice by immunization with plasmid DNA containing sequence derived from a Chinese genotype III/2a isolate of hepatitis C virus., PMID:11593587
Molecular design and immunogenicity studies of multiple antigenic peptide corresponding to envelope glycoprotein hypervariable region 1 of hepatitis C virus., PMID:11503045
Predominance of antibodies to hepatitis C virus envelope proteins in various disease statuses of hepatitis C., PMID:11394572
[Expression of glycoprotein hepatitis C virus in mammalian cell and application of purified protein for detection of antibody against E2 in hepatitis C patients]., PMID:10715790
Antibody response to E2/NS1 hepatitis C virus protein in patients with acute hepatitis C., PMID:9076628
Significance of anti-E2 in the diagnosis of HCV infection in patients on maintenance hemodialysis: anti-E2 is frequently detected among anti-HCV antibody-negative patients., PMID:8959633
Lack of correlation between different hepatitis C virus screening and confirmatory assays., PMID:8793841
Quantitative analysis of antibody to hepatitis C virus envelope 2 glycoprotein in patients with chronic hepatitis C virus infection., PMID:8621173
Fraction-specific populations of the hypervariable region of the hepatitis C virus in a patient with cryoglobulinemia., PMID:7595420
Sequence evolution of the hypervariable region in the putative envelope region E2/NS1 of hepatitis C virus is correlated with specific humoral immune responses., PMID:7815542
The serology of hepatitis C virus (HCV) infection: antibody crossreaction in the hypervariable region 1., PMID:7503672
Influence of antibodies to the hypervariable region of E2/NS1 glycoprotein on the selective replication of hepatitis C virus in chimpanzees., PMID:7941335
[Evolution of hepatitis C virus (HCV) viremia and adaptation of HCV in persistent infection in patients with acute hepatitis]., PMID:7521430
Analysis of hepatitis C virus capsid, E1, and E2/NS1 proteins expressed in insect cells., PMID:8212557
Hypervariable 5'-terminus of hepatitis C virus E2/NS1 encodes antigenically distinct variants., PMID:7689636
[Hepatitis C]., PMID:8345654
Antigenic regions within the hepatitis C virus envelope 1 and non-structural proteins: identification of an IgG3-restricted recognition site with the envelope 1 protein., PMID:7680297
[Expression of hepatitis C virus genome]., PMID:7681882
Expression of HCV E2/NS1 protein as a fusion protein with maltose binding protein: detection of anti-E2/NS1 antibody in chronic liver disease., PMID:7686121
Expression of MBP-HCV NS1/E2 fusion protein in E. coli and detection of anti-NS1/E2 antibody in type C chronic liver disease., PMID:1314578
For research use only. Not for human or drug use.
