Research Grade Barzolvolimab

Catalog No.

DHC83101

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Chimeric

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

Mast/stem cell growth factor receptor Kit, p145 c-kit, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, KIT, PBT, Piebald trait protein, Proto-oncogene c-Kit, SCFR, CD117

Concentration

1.47 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P10721

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

CDX-0159 CAS: 2438203-51-9

Clone ID

Barzolvolimab

Depletion of mast cells with barzolvolimab, an anti-KIT antibody, does not affect mast cell progenitors., PMID:40439351

Anti-KIT Barzolvolimab for Chronic Spontaneous Urticaria., PMID:40415544

New and Emerging Biologics and Jak Inhibitors for the Treatment of Prurigo Nodularis: A Narrative Review., PMID:40282922

Update on the Treatment of Chronic Spontaneous Urticaria., PMID:40074986

Therapies for Chronic Spontaneous Urticaria: Present and Future Developments., PMID:39598410

Emerging Therapeutics in Chronic Urticaria., PMID:38937013

Chronic Prurigo., PMID:38722190

Prurigo nodularis: new insights into pathogenesis and novel therapeutics., PMID:38345154

Inhibition of KIT for chronic urticaria: a status update on drugs in early clinical development., PMID:37897679

Chronic Prurigo Including Prurigo Nodularis: New Insights and Treatments., PMID:37717255

Anti-KIT antibody, barzolvolimab, reduces skin mast cells and disease activity in chronic inducible urticaria., PMID:36385701

Document Download

Research Grade Barzolvolimab.pdf