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Anti-Human C1q Complement Polyclonal Antibody, FITC

Catalog #:   PHD01041 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IF, WB
Overview

Catalog No.

PHD01041

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human C1q (Ala28-Ala245).

Conjugation

FITC

Target

C1Q, Complement C1q

Purification

Purified by antigen affinity column.

Applications

ELISA, IF, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with 0 antibody (PHD01041) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 25 kDa
    Observed MW: 25 kDa
  • Immunohistochemical
    Immunohistochemical analysis of human bladder cancer stained for C1QA with PHD01041.
References

A multicenter prospective cohort study evaluating impact of an active delisting strategy to enable kidney transplantation in wait-listed candidates with calculated Panel Reactive Antibody ≥ 99.9., PMID:40484353

Complement in anti-glomerular basement membrane glomerulonephritis., PMID:40469278

Evolving understanding of Guillain-Barré syndrome pathophysiology and the central role of the classical complement pathway in axonal injury., PMID:40438570

C1q Binds to CD4+ T Cells and Inhibits the Release of Pro-Inflammatory Cytokines: Role in the Pathogenesis of Systemic Lupus Erythematosus., PMID:40429614

A novel complement C1q A chain from marbled flounder, Pseudopleuronectes yokohamae: genome characterization, expression and potential role in antibacterial immunity., PMID:40349809

Deposition of complement regulators on the surface of Plasmodium falciparum merozoites depends on the immune status of the host., PMID:40294075

Complement updates in optic neuritis., PMID:40206291

Direct immunofluorescence of labial gland in diagnosis of Sjögren's disease., PMID:40172814

Clinical and immunological biomarkers can identify proliferative changes and predict renal flares in lupus nephritis., PMID:40165257

IgM Variant of Proliferative Glomerulonephritis With Monoclonal Immunoglobulin Deposits: A Case Series., PMID:40147751

Anti-C1s autoantibodies as complementary serologic biomarker in lupus nephritis., PMID:40132784

Rare presentation of hypocomplementaemic urticarial vasculitis syndrome (HUVS) overlapping with systemic erythematosus lupus (SLE) and small lymphocytic lymphoma (SLL)., PMID:39933844

Two siblings with monogenic lupus due to C1qC deficiency and case based review., PMID:39843834

Non-canonical Roles of Complement in the CNS: From Synaptic Organizer to Presynaptic Modulator of Glutamate Transmission., PMID:39817397

Anti-C1q antibodies in IgG4-related disease are common and associated with renal involvement and cutaneous small-vessel vasculitis., PMID:39798124

Enhancing Neuron Activity Promotes Functional Recovery by Inhibiting Microglia-Mediated Synapse Elimination After Stroke., PMID:39772780

Enhancing complement activation by therapeutic anti-tumor antibodies: Mechanisms, strategies, and engineering approaches., PMID:39742715

A case of neuron-derived neurotrophic factor-positive, syphilis-related membranous nephropathy that achieved spontaneous remission., PMID:39733185

Lupus nephritis and related renal disease: review from case series., PMID:39699701

Immune complexome analysis reveals an autoimmune signature predictive of COVID-19 severity., PMID:39689808

Characteristics of glomerulonephritis with dominant C1q precipitation compared to corresponding glomerulonephritis without C1q staining on immunofluorescent examination., PMID:39639420

A novel multiple marker microarray analyzer and methodology to predict major obstetric syndromes using surface markers of circulating extracellular vesicles from maternal plasma., PMID:39607297

A Case of Hypocomplementemic Urticarial Vasculitis Syndrome With Severe Renal and Gastrointestinal Involvement., PMID:39575061

Correlation of autoimmune response and immune system components in the progression of IgA nephropathy: A comparative study., PMID:39566436

Immune Markers and Inflammatory Cytokines in Granulomatous Lobular Mastitis: A Case-Control Study., PMID:39553312

Downhill running does not alter blood C1q availability or complement-dependent cytotoxicity of therapeutic monoclonal antibodies against haematological cancer cell lines in vitro., PMID:39548231

Beyond Recycling Antibodies: Crovalimab's Molecular Design Enables Four-Weekly Subcutaneous Injections for PNH Treatment., PMID:39519232

C1q Binding Ability for Prior Risk Assessment of Acute Antibody-Mediated Rejection in ABO-Incompatible Kidney Transplantation., PMID:39474587

Hematopoietic Stem Cell Transplantation for C1q Deficiency: A Study on Behalf of the EBMT Inborn Errors Working Party., PMID:39470951

Circulating Immune Complexes and Complement Activation in Sensitized Kidney Transplant Recipients., PMID:39456685

Immunoglobulin G and Complement as Major Players in the Neurodegeneration of Multiple Sclerosis., PMID:39456143

The evolution of flexibility and function in the Fc domains of IgM, IgY, and IgE., PMID:39445016

C1q-Fixing De Novo Donor Specific Antibodies in Therapeutic Management of Chronic Antibody-Mediated Rejection Postkidney Transplantation., PMID:39443200

Case Report: Hypocomplementemic urticarial vasculitis syndrome in a pediatric patient with complement factor 1 deficiency., PMID:39376673

The importance of IgG glycosylation-What did we learn after analyzing over 100,000 individuals., PMID:39364834

Interrogating post-transplant donor HLA-specific antibody characteristics and effector functions using clinical bead assays., PMID:39357467

Macrophages Promote Atherosclerosis Development by Inhibiting CD8T Cell Apoptosis., PMID:39345351

IgG4 glycosylation contributes to the pathogenesis of IgG4 Hashimoto's thyroiditis via the complement pathway., PMID:39316722

Systematic analysis of Fc mutations designed to enhance binding to Fc-gamma receptors., PMID:39306747

A systems serology approach to identifying key antibody correlates of protection from cerebral malaria in Malawian children., PMID:39267089

ASTCT Consensus Recommendations on Testing and Treatment of Patients with Donor-specific Anti-HLA Antibodies., PMID:39260570

Antibody density on bacteria regulates C1q recruitment by monoclonal IgG but not IgM., PMID:39233515

Novel Flow Cytometry Method Detecting Complement C1q Bound to Blood Type A/B IgG Antibody for Preventing Severe Antibody-Mediated Rejection in ABO-Incompatible Kidney Transplantation., PMID:39189233

The fate of immune complexes in membranous nephropathy., PMID:39185424

Profile of juvenile systemic lupus erythematosus patients with a special reference to monogenic lupus and lupus nephritis: a cross-sectional study., PMID:39180524

Childhood-onset systemic lupus erythematosus associated with inborn errors of immunity: One or several conditions?, PMID:39178162

[Correlation of anti-C1q antibodies with active systemic lupus erythematosus and lupus nephritis in children]., PMID:39148388

Antibody mechanisms of protection against malaria in RTS,S-vaccinated children: a post-hoc serological analysis of phase 2 trial., PMID:39127054

Immunoglobulin G glycosylation and its alterations in aging-related diseases., PMID:39126246

Complete Description of the Three Pathways of the Complement System in a Series of 430 Patients with Rheumatoid Arthritis., PMID:39125933

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 360

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human C1q Complement Polyclonal Antibody, FITC [PHD01041]
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