Catalog No.
RHC19701
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Applications
ELISA, IP
Target
AGEs, Advanced glycation end products, CML, Nε-(Carboxymethyl)-L-lysine, N6-(carboxymethyl)-L-lysine, CAS: 5746-04-3
Concentration
2.33 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
CAS: 5746-04-3
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
6C7
Background
Nε-(1-Carboxymethyl)-L-lysine (CML) is an advanced glycation end product (AGE), produced by the oxidative modification of glycated proteins during oxidative stress. Levels of CML increase with aging and during diabetes, cancer, vascular disease, and other pathologies marked by oxidative stress.
Note
For research use only.
Seroprevalence against measles, Austria, stratified by birth years 1922 to 2024., PMID:40276882
Skin Punch as a Potential Diagnostic Tool for Peripheral Neuropathies of Dogs: Set up of an Indirect Immunofluorescence Protocol on Formalin-Fixed Paraffin-Embedded (FFPE) Biopsy., PMID:40284793
First Serologic Evidence of West Nile Virus and Usutu Virus Circulation Among Dogs in the Bulgarian Danube Region and Analysis of Some Risk Factors., PMID:40284875
Epidemiological Burden of Hepatitis Delta Virus in the United States., PMID:40298139
Epstein-Barr Virus Seroprevalence in Thailand: A Temporal and Global Perspective with Health Care and Economic Correlations., PMID:40300594
Adherence and persistence among patients with hereditary angioedema receiving long-term prophylaxis in the United States., PMID:40300843
Enrichment of human IgA-coated bacterial vesicles in ulcerative colitis as a driver of inflammation., PMID:40301356
Alirocumab in Adult Patients With Hyperlipidemia After Liver Transplantation: A Short-term Observation., PMID:40307128
Serosurveillance to Support HPV Vaccination in England., PMID:40309406
Neferine inhibits PRRSV infection by disrupting p65 nuclear translocation., PMID:40311944
Intestinal mucosal immune responses induced by novel oral poliovirus vaccine type 2 and Sabin monovalent oral poliovirus vaccine type 2: an analysis of data from four clinical trials., PMID:40318674
Inhibition of DNA glycoxidation by mannitol and Pyridoxamine: Implications for DNA-antibody development in diabetes and diabetic retinopathy., PMID:40320156
Longitudinal assessment of immunogenicity of inactivated COVID-19 booster immunization and breakthrough infection in blood donors: A multicenter study from 2021 to 2023., PMID:40323225
[Screening of High-Titer IgG Antibodies to 2019-nCoV among Voluntary Blood Donors in Zunyi]., PMID:40326129
Real-world efficacy and safety of burosumab in tumor-induced osteomalacia: case series from an early access program., PMID:40329993
Immunogenicity and Safety of Influenza and COVID-19 Multicomponent Vaccine in Adults ≥50 Years: A Randomized Clinical Trial., PMID:40332892
Epidemiology and approaches for management of relapsed and refractory multiple myeloma in Gulf Countries: a narrative review and insights from the Gulf multiple myeloma experts., PMID:40354099
A novel plant-derived recombinant COBRA infectious bronchitis virus spike protein can elicit a strong immune response in chickens., PMID:40358746
Age dependent susceptibility and immune responses to La Crosse virus infection in non-human primates., PMID:40360698
Compartmentalised mucosal and blood immunity to SARS-CoV-2 is associated with high seroprevalence before the Delta wave in Africa., PMID:40379979
Becoming attack-free further improves health-related quality of life in patients with hereditary angioedema receiving garadacimab., PMID:40380356
Garadacimab improves long-term health-related quality of life in patients with hereditary angioedema., PMID:40380363
Estimating population immunity to SARS-CoV-2 by random sampling from primary and secondary healthcare in Scotland, May 2024., PMID:40381379
Comparative effectiveness of romosozumab versus teriparatide for fracture prevention: A new-user, active comparator design., PMID:40381877
Direct Comparison of Alternative Blood-Based Approaches for Early Detection and Diagnosis of HPV-Associated Head and Neck Cancers., PMID:40392113
Immune impacts of infant whole-cell and acellular pertussis vaccination on co-administered vaccines., PMID:40414565
Enteral immunization with live bacteria reprograms innate immune cells and protects neonatal foals from pneumonia., PMID:40415003
From infection to autoimmunity: can COVID-19 spark new auto-immune conditions?, PMID:40415761
Development and identification of porcine monoclonal antibodies against PEDV from single B cells., PMID:40424889
Anti-NMDA Receptor Encephalitis: A Narrative Review., PMID:40426689
Evaluating SARS-CoV-2 T Cell Immunity in COVID-19-Naive Vaccinated Individuals with and Without Spike Protein IgG Antibodies., PMID:40430736
Dissection and Whole-Mount Immunofluorescent Staining of Mouse Hind Paw Muscles for Neuromuscular Junction Analysis., PMID:40432760
Defining three dimensional chromatin structures of pediatric and adolescent B cells using primary B cell and EBV-immortalized B cell reference genomes., PMID:40437445
Enhancing systemic lupus erythematosus treatment outcomes with an early initiation of belimumab: insights from a multicenter retrospective study within the first five years., PMID:40442811
Preclinical Safety., PMID:40445826
Impact of age and immune status on the accuracy of rapid diagnostic tests for visceral leishmaniasis in Brazil., PMID:40455709
Animal models of autoimmune encephalitis., PMID:40472632
Clinical characteristics and treatment response of treatment requiring retinopathy of prematurity (ROP) in Big Premature Infants in Turkiye: BIG-ROP Study Group Report No 2 (BIG-ROP STUDY)., PMID:40473274
Immune age is correlated with decreased TCR clonal diversity and antibody response to SARS-CoV-2., PMID:40481111
[Diagnosis, treatment, and genetic analysis of five cases of primary atypical hemolytic uremic syndrome]., PMID:40484823
Uveitis associated with juvenile idiopathic arthritis and chronic idiopathic uveitis in children: A retrospective cohort study., PMID:40491729
Hashimoto's thyroiditis and its activity status influence the assessment of lymph node metastasis of thyroid cancer., PMID:40496557
Laboratory-confirmed respiratory syncytial virus (RSV) hospitalizations: a national all ages cross-section evaluation, 2020-2024., PMID:40500807
Enhancing Wnt signaling lowers fracture incidence in a severe mouse model of Osteogenesis Imperfecta., PMID:40501669
Oral Administration of Hydrolyzed Egg Yolk Peptides With Low Molecular Weight Increased Bone Density by Regulating Bone Metabolism and Immune Responses., PMID:40504632
The waning of maternal measles antibodies: a multi-country maternal-infant seroprevalence study., PMID:40513621
[Clinical analysis of 4 cases of juvenile dermatomyositis complicated with massive hemorrhage of digestive tract]., PMID:40518160
Seroprevalence of Neospora caninum infection in cattle and yaks in the northern mountainous regions of Kyrgyzstan., PMID:40518251
Type 1 diabetes mellitus prevention: present and future., PMID:40527975
For research use only. Not for human or drug use.
