Catalog No.
EHC43601
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Asp688
Predicted molecular weight
77.66 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P09871
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C1 esterase, Complement C1s subcomponent, C1S, Complement component 1 subcomponent s
Note
For research use only.
Identification of key eRNAs for intervertebral disc degeneration by integrated multinomial bioinformatics analysis., PMID:38704519
Detection of genetic mutations underlying early-onset systemic lupus erythematosus., PMID:38739464
C1s targeting antibodies inhibit the growth of cutaneous squamous carcinoma cells., PMID:38866870
The evolving management algorithm for the patient with newly diagnosed cold agglutinin disease., PMID:38872338
[Cold agglutinin disease: pathology, diagnosis, and treatment]., PMID:38960651
The Crystal Structure of the Michaelis-Menten Complex of C1 Esterase Inhibitor and C1s Reveals Novel Insights into Complement Regulation., PMID:38995166
sMR and PTX3 levels associate with COVID-19 outcome and survival but not with Long COVID., PMID:39027374
Plasma SCUBE2 as a novel biomarker associates with survival outcomes in patients with sepsis-associated acute kidney injury., PMID:39034165
DNA methylome analysis reveals epigenetic alteration of complement genes in advanced metabolic dysfunction-associated steatotic liver disease., PMID:39048522
Recombinant Ixodes scapularis Calreticulin Binds Complement Proteins but Does Not Protect Borrelia burgdorferi from Complement Killing., PMID:39057787
A novel missense variant in CAT gene causing acatalasemia with gangrenous periodontitis (Takahara's disease)., PMID:39079473
Causal relationship between complement C1QB and colorectal cancer: a drug target Mendelian randomization study., PMID:39109334
The Establishment of Complement System Is from Gene Duplication and Domain Shuffling., PMID:39125697
Pharmacokinetics, pharmacodynamics, safety, and tolerability of a single-dose riliprubart, an anti-C1s humanized monoclonal antibody in East-Asian adults: results from a Phase 1, randomized, open-label trial., PMID:39171350
Pan-cancer analysis identifies venous thromboembolism-related genes F3, PLAT, and C1S as potential prognostic biomarkers for glioblastoma and lower grade glioma., PMID:39179711
Immunomodulatory potential of cytokine-licensed human bone marrow-derived mesenchymal stromal cells correlates with potency marker expression profile., PMID:39208292
Elevated C1s/C1-INH in serum and plasma of myasthenia gravis patients., PMID:39255718
Immunodeficiency: Complement disorders., PMID:39294906
[New drugs for the treatment of primary immune thrombocytopenia]., PMID:39358266
Protein biomarkers in assessing kidney quality before transplantation‑current status and future perspectives (Review)., PMID:39370783
Autoimmune haemolytic anaemias., PMID:39487134
Torque Teno Virus Control by the Classical Pathway of Complement Activation-A Retrospective Analysis From a First-in-Human Trial Utilizing Sutimlimab., PMID:39503157
Downhill running does not alter blood C1q availability or complement-dependent cytotoxicity of therapeutic monoclonal antibodies against haematological cancer cell lines in vitro., PMID:39548231
Maternal Serum SCUBE-1: A Novel Ischemic Marker in Preeclampsia., PMID:39590594
[Study on serum proteomic characteristics of workers with rare earth samarium oxide pneumoconiosis]., PMID:39604234
Africanized honeybee venom (Apis mellifera) promotes human complement activation split products storm., PMID:39606222
Divergent changes in complement pathway gene expression in schizophrenia and bipolar disorder: Links to inflammation and neurogenesis in the subependymal zone., PMID:39616737
[Maggot alleviates imiquimod-induced psoriasis-like skin lesions in mice by inhibiting immune stress and complement activation]., PMID:39623267
IGHG4: innovative diagnostic biomarkers for iron overload in β-thalassemia patients., PMID:39676317
The assessment of the relationship between the development of cardiovascular diseases and SCUBE-1 level in individuals exposed to loud noise., PMID:39705419
Complement classical and alternative pathway activation contributes to diabetic kidney disease progression: a glomerular proteomics on kidney biopsies., PMID:39753879
Avian pathogenic Escherichia coli alters complement gene expression in chicken erythrocytes., PMID:39757946
Unraveling antibody-induced structural dynamics in the ADAMTS13 CUB1-2 domains via HDX-MS., PMID:39774799
N-glycosylation in the SERPIN domain of the C1-esterase inhibitor in hereditary angioedema., PMID:39823539
[Berberine ameliorates coronary artery endothelial cell injury in Kawasaki disease through complement and coagulation cascades]., PMID:39825659
Evaluating SCUBE-1 as Predictive Biomarker for Hypertension-Mediated Organ Damage: A Comparative Study., PMID:39867205
Complement function and activation in human serum and plasma collected in different blood collection tubes., PMID:39921078
Guianensin, a Blackfly Salivary Protein, Inhibits the Lectin Pathway of Complement., PMID:39924859
Management of cardiovascular disease by cerium oxide nanoparticles via alleviating oxidative stress and adipokine abnormalities., PMID:39962072
Urine complement analysis implies complement activation is involved in membranous nephropathy., PMID:40018357
Mendelian randomization identifies proteins involved in neurodegenerative diseases., PMID:40037332
The structural characteristics and expression characteristics of C1S in response to GCRV infection in grass carp., PMID:40058677
Anti-C1s autoantibodies as complementary serologic biomarker in lupus nephritis., PMID:40132784
Impact of a Heterozygous C1RR301P/WT Mutation on Collagen Metabolism and Inflammatory Response in Human Gingival Fibroblasts., PMID:40214433
Proteomic Profiling of Age-Related Proteins Following Extracorporeal Apheresis., PMID:40233791
Protective Vaccination of Mice Against Blood-Stage Malaria Impacts Hepatic Expression of Genes Encoding Acute-Phase Proteins and IL-6 Family Members., PMID:40243929
Investigating the mechanisms of yinchen in the treatment of immune hemolysis: Quercetin's role in complement inhibition and suppression of IL-6/STAT3 signaling., PMID:40267837
Modular activation of macrophage-like cells by beta-2-microglobulin via mitochondria and the cGAS-STING pathway., PMID:40345004
Heterologous Surface Display Reveals Conserved Complement Inhibition and Functional Diversification of Borrelia burgdorferi Elp Proteins., PMID:40376887
Identification of a Novel Homozygous C1QB Mutation in an Iranian Girl: Expanding the Clinical Spectrum of C1q Deficiency., PMID:40506420
For research use only. Not for human or drug use.
