Catalog No.
EWK07001
Expression system
Mammalian Cells
Species
Monkey
Protein length
CD49b [Met1-Pro908] & CD61 [Met1-Pro717]
Predicted molecular weight
99.55 kDa, 80.02 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
EHH58199.1 & XP_014974842.2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Collagen receptor, ITGA2, VLA-2 subunit alpha, CD49B, CD49 antigen-like family member B, Platelet membrane glycoprotein Ia, GPIa, Integrin alpha-2, CD49b, GPIIIa, Integrin beta-3, CD61, ITGB3, Platelet membrane glycoprotein IIIa, GP3A
Enhanced engraftment and immunomodulatory effects of integrin alpha-2-overexpressing mesenchymal stromal cells in lipopolysaccharide-induced acute lung injury., PMID:40462215
Unique motif Sequences for early diagnosis of preeclampsia., PMID:40348314
Enhancer-Associated LncRNA-ITGA2 Promotes Vascular Remodeling Through ITGA2., PMID:40321134
KLF7-regulated ITGA2 as a therapeutic target for inhibiting oral cancer stem cells., PMID:40316546
Impact of different chemical debridement agents on early cellular responses to titanium dental implants: A transcriptome-based in vitro study on peri-implant tissue regeneration., PMID:40288111
Evaluation of Integrin Glycovariants as Biomarkers of Metastasis, Invasion, and Therapy Stratification in Head and Neck Squamous Cell Carcinoma., PMID:40287842
Anlotinib inhibits c-MET and ITGA2 in the treatment of anaplastic thyroid carcinoma., PMID:40281512
Establishment of a Panel of Human Cell Lines to Identify Cellular Receptors Used by Enteroviruses to Infect Cells., PMID:39940693
MUC1 and MUC4 expression are inversely correlated and trigger immunological response and transport pathways in adult-type diffuse gliomas., PMID:39889447
[Clinical and genetic associations in patients with non-cardioembolic ischemic stroke]., PMID:39831357
hsa_circ_0001599 promotes odontogenic differentiation of human dental pulp stem cells by increasing ITGA2 expression and stability., PMID:39825107
Inflammatory Response of THP1 and U937 Cells: The RNAseq Approach., PMID:39768153
Fructo-Oligosaccharides Enhance the Expression of Genes Related to Focal Adhesion- and Inflammation-Pathways in Small Intestinal Absorptive Caco-2 Cells., PMID:39756968
The associations of candidate gene polymorphisms with aspirin resistance in patients with ischemic disease: a meta-analysis., PMID:39617913
Comparative single-cell multiome identifies evolutionary changes in neural progenitor cells during primate brain development., PMID:39481377
Blockade of ITGA2/3/5 Promotes Adipogenic Differentiation of Human Adipose-derived Mesenchymal Stem Cells., PMID:39316261
Matrix stiffness regulates the protein profile of extracellular vesicles of pancreatic cancer cell lines., PMID:39279557
PSAT1 Promotes Metastasis via p-AKT/SP1/ITGA2 Axis in Estrogen Receptor-Negative Breast Cancer Cell., PMID:39199378
Fibroblast growth factor 2 enhances BMSC stemness through ITGA2-dependent PI3K/AKT pathway activation., PMID:39188080
SLC4A4 as a novel biomarker involved in immune system response and lung adenocarcinoma progression., PMID:39083932
Cancer-associated fibroblasts (CAFs) gene signatures predict outcomes in breast and prostate tumor patients., PMID:38937754
Avellanin A Has an Antiproliferative Effect on TP-Induced RWPE-1 Cells via the PI3K-Akt Signalling Pathway., PMID:38921586
Whole-exome sequencing screening for candidate genes and variants associated with primary sporadic keratoconus in Chinese patients., PMID:38908538
Selumetinib overcomes ITGA2-induced 5-fluorouracil resistance in colorectal cancer., PMID:38889513
Comprehensive evaluation of genes related to basement membrane in hepatocellular carcinoma., PMID:38870261
Landscape of extrachromosomal circular DNAs, transcriptome, and proteome analysis reveals insights into alcoholic liver cirrhosis., PMID:38782221
MUC1 promotes cervical squamous cell carcinoma through ERK phosphorylation-mediated regulation of ITGA2/ITGA3., PMID:38702644
Genkwanin alleviates intervertebral disc degeneration via regulating ITGA2/PI3K/AKT pathway and inhibiting apoptosis and senescence., PMID:38640717
Integrated bioinformatics analysis reveals upregulated extracellular matrix hub genes in pancreatic cancer: Implications for diagnosis, prognosis, immune infiltration, and therapeutic strategies., PMID:38639039
An integrated approach to understand the regulatory role of miR-27 family in breast cancer metastasis., PMID:38565418
Ageing impairs the regenerative capacity of regulatory T cells in mouse central nervous system remyelination., PMID:38467607
Spatial transcriptomics reveals prognosis-associated cellular heterogeneity in the papillary thyroid carcinoma microenvironment., PMID:38426403
Radiotherapy Resistance of 3D Bioprinted Glioma via ITGA2/p-AKT Signaling Pathway., PMID:38288911
Dampened Regulatory Circuitry of TEAD1/ITGA1/ITGA2 Promotes TGFβ1 Signaling to Orchestrate Prostate Cancer Progression., PMID:38169150
Gaining Insights into Inherited Bleeding Disorders of Complex Etiology in Pediatric Patients: Whole-Exome Sequencing as First-Line Investigation Tool., PMID:38158197
[Association of polymorphic variants of hemostatic system genes with the course of COVID-19]., PMID:38156578
ITGA2 as a prognostic factor of glioma promotes GSCs invasion and EMT by activating STAT3 phosphorylation., PMID:38142122
Selection of potential targets for stratifying congenital pulmonary airway malformation patients with molecular imaging: is MUC1 the one?, PMID:38123235
CXCL10-based gene cluster model serves as a potential diagnostic biomarker for premature ovarian failure., PMID:38107572
Differentiated neuroblastoma cells remain epigenetically poised for de-differentiation to an immature state., PMID:38095019
SDC1 and ITGA2 as novel prognostic biomarkers for PDAC related to IPMN., PMID:37907515
Lineage specific extracellular vesicle-associated protein biomarkers for the early detection of high grade serous ovarian cancer., PMID:37884576
High expression ITGA2 affects the expression of MET, PD-L1, CD4 and CD8 with the immune microenvironment in pancreatic cancer patients., PMID:37881431
Integrin α2 promotes immune escape in non-small-cell lung cancer by enhancing PD-L1 expression in exosomes to inhibit CD8 + T-cell activity., PMID:37804164
Transcriptomic analysis identifies four novel receptors potentially linking endometrial cancer with polycystic ovary syndrome and generates a transcriptomic atlas., PMID:37737665
Rapid generation of functional nanovesicles from human trophectodermal cells for embryo attachment and outgrowth., PMID:37698557
Skeletal muscle integrin expression in non-obese men with varying degrees of insulin sensitivity., PMID:37438145
The coagulation-related genes for prognosis and tumor microenvironment in pancreatic ductal adenocarcinoma., PMID:37386391
Oxidative stress induced by Pollonein-LAAO, a new L-amino acid oxidase from Bothrops moojeni venom, prompts prostate tumor spheroid cell death and impairs the cellular invasion process in vitro., PMID:37364850
BACH1 promotes lung adenocarcinoma cell metastasis through transcriptional activation of ITGA2., PMID:37311571
For research use only. Not for human or drug use.
