Anti-SLCO1B1/LST-1/OATP-2 Polyclonal Antibody

Catalog No.

PHK07601

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SLCO1B1/LST-1/OATP-2 (Phe426-Phe537).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

LST1,OATP1B1,OATP2,SLCO1B1,Solute carrier family 21 member 6,OATP-2,Sodium-independent organic anion-transporting polypeptide 2,LST-1,SLC21A6,OATP-C,OATPC,Solute carrier organic anion transporter family member 1B1,Liver-specific organic anion transporter 1

Purification

Purified by antigen affinity column.

Accession

Q9Y6L6

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Rapid Detection of SLCO1B1 Polymorphisms Using Duplex Fluorescence Melting Curve Analysis: Implications for Personalized Drug Dosing in Clinical Settings., PMID:39512267

Genetic variants associated with immune-mediated liver injury from checkpoint inhibitors., PMID:39185906

Epidemiological and genetic features of anti-3‑hydroxy-3-methylglutaryl-CoA reductase necrotizing myopathy: Single-center experience and literature review., PMID:35487805

Hyperlipidemia patients carrying LDLR splicing mutation c.1187-2A>G respond favorably to rosuvastatin and PCSK9 inhibitor evolocumab., PMID:35441343

The SNPs rs429358 and rs7412 of APOE gene are association with cerebral infarction but not SNPs rs2306283 and rs4149056 of SLCO1B1 gene in southern Chinese Hakka population., PMID:32891149

Redox-related Molecular Mechanism of Sensitizing Colon Cancer Cells to Camptothecin Analog SN38., PMID:32878804

OATP1B3 Expression and Function is Modulated by Coexpression with OCT1, OATP1B1, and NTCP., PMID:32482756

Comprehensive preclinical pharmacokinetic evaluations of trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate, in cynomolgus monkeys., PMID:30351177

Organic anion transporting polypeptide 1B3 can form homo- and hetero-oligomers., PMID:28644885

Down-regulation of OATP1B proteins correlates with hyperbilirubinemia in advanced cholestasis., PMID:26191226

Quantification of proteins by flow cytometry: Quantification of human hepatic transporter P-gp and OATP1B1 using flow cytometry and mass spectrometry., PMID:25916617

Abnormal splicing of NEDD4 in myotonic dystrophy type 2: possible link to statin adverse reactions., PMID:24907641

Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects., PMID:24324551

N-Glycosylation dictates proper processing of organic anion transporting polypeptide 1B1., PMID:23285087

Liver enzyme abnormalities and associated risk factors in HIV patients on efavirenz-based HAART with or without tuberculosis co-infection in Tanzania., PMID:22808112

Profiling of drug-metabolizing enzymes/transporters in CD33+ acute myeloid leukemia patients treated with Gemtuzumab-Ozogamicin and Fludarabine, Cytarabine and Idarubicin., PMID:22584460

OATP 1B1/1B3 expression in hepatocellular carcinomas treated with orthotopic liver transplantation., PMID:21691816

Further characterization of the electrogenicity and pH sensitivity of the human organic anion-transporting polypeptides OATP1B1 and OATP1B3., PMID:21173039

Complex multifactorial nature of significant hyperbilirubinemia in neonates., PMID:19858149

[Pharmacogenomics]., PMID:19507510

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