Catalog No.
PHJ38101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD365/KIM-1/TIM-1/HAVCR1 (Ser21-Gly295).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
TIM,Kidney injury molecule 1,T-cell immunoglobulin mucin receptor 1,KIM1,KIM-1,TIM1,TIMD1,HAVCR1,T-cell immunoglobulin and mucin domain-containing protein 1,T-cell membrane protein 1,CD365,Hepatitis A virus cellular receptor 1,HAVcr-1,TIMD-1,TIM-1
Purification
Purified by antigen affinity column.
Accession
Q96D42
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Multifunctional cerium nanolabels in electrochemical immunosensing with improved robustness and performance: determination of TIM-1 in colorectal cancer scenarios as a case study., PMID:40107988
Glomerular Injury Is Associated with Severe Courses of Orthohantavirus Infection., PMID:39204293
miR-142 Targets TIM-1 in Human Endothelial Cells: Potential Implications for Stroke, COVID-19, Zika, Ebola, Dengue, and Other Viral Infections., PMID:36142146
Altered Tim-1 and IL-10 Expression in Regulatory B Cell Subsets in Type 1 Diabetes., PMID:35754999
The Phosphatidylserine Receptor TIM-1 Enhances Authentic Chikungunya Virus Cell Entry., PMID:34359995
SARS-CoV-2 pseudovirus infectivity and expression of viral entry-related factors ACE2, TMPRSS2, Kim-1, and NRP-1 in human cells from the respiratory, urinary, digestive, reproductive, and immune systems., PMID:34324210
Evaluation of Human Kidney Injury Molecule 1 (hKIM-1) Expression in Tumors From Various Organs by Messenger RNA In Situ Hybridization., PMID:33608720
Analysis of the association between kidney injury biomarkers concentration and nephritis in immunoglobulin A vasculitis: A pediatric cohort study., PMID:32627422
Safety and efficacy of CDX-014, an antibody-drug conjugate directed against T cell immunoglobulin mucin-1 in advanced renal cell carcinoma., PMID:32472319
Blockade of TIM-1 on the donor graft ameliorates graft-versus-host disease following hematopoietic cell transplantation., PMID:31714958
Diagnostic roles of urinary kidney injury molecule 1 and soluble C5b-9 in acute tubulointerstitial nephritis., PMID:31291122
Alterations in immune and renal biomarkers among workers occupationally exposed to low levels of trichloroethylene below current regulatory standards., PMID:30971425
Tumor-derived exosomal HMGB1 fosters hepatocellular carcinoma immune evasion by promoting TIM-1+ regulatory B cell expansion., PMID:30526680
A Phage Display-Identified Peptide Selectively Binds to Kidney Injury Molecule-1 (KIM-1) and Detects KIM-1-Overexpressing Tumors in vivo., PMID:30282451
Association Between C1q, TRAIL, and Tim-1 Gene Polymorphisms and Systemic Lupus Erythematosus., PMID:30183357
Markers of Glomerular and Tubular Damage in the Early Stage of Kidney Disease in Type 2 Diabetic Patients., PMID:30158836
TIM-1 Mediates Dystroglycan-Independent Entry of Lassa Virus., PMID:29875238
Highly sensitive electrochemiluminescence immunosensor based on ABEI/H2O2 system with PFO dots as enhancer for detection of kidney injury molecule-1., PMID:29852472
HAVCR1 (CD365) and Its Mouse Ortholog Are Functional Hepatitis A Virus (HAV) Cellular Receptors That Mediate HAV Infection., PMID:29437974
Determinants in the Ig Variable Domain of Human HAVCR1 (TIM-1) Are Required To Enhance Hepatitis C Virus Entry., PMID:29321304
Proteomic Profiling for Cardiovascular Biomarker Discovery in Orthostatic Hypotension., PMID:29295851
Tissue and urinary KIM-1 relate to tumor characteristics in patients with clear renal cell carcinoma., PMID:29052086
Resveratrol-loaded nanoparticles conjugated with kidney injury molecule-1 as a drug delivery system for potential use in chronic kidney disease., PMID:28884615
[Kidney injury molecules (KIM-1, MCP-1) and type IV collagen in the assessment of activity of antineutrophil cytoplasmic antibody-associated glomerulonephritis]., PMID:28745689
Tim-1+ B cells suppress T cell interferon-gamma production and promote Foxp3 expression, but have impaired regulatory function in coronary artery disease., PMID:28736945
TIM-1 Promotes Hepatitis C Virus Cell Attachment and Infection., PMID:27807228
Single-Multiplex Detection of Organ Injury Biomarkers using SPRi based Nano-Immunosensor., PMID:27796342
Roles of T-cell Immunoglobulin and Mucin Domain Genes and Toll-like Receptors in Wheezy Children with Mycoplasma pneumoniae Pneumonia., PMID:27185658
CD19+ Tim-1+ B cells are decreased and negatively correlated with disease severity in Myasthenia Gravis patients., PMID:27677768
Kidney Injury Molecule-1 Enhances Endocytosis of Albumin in Renal Proximal Tubular Cells., PMID:26332568
Biology of Zika Virus Infection in Human Skin Cells., PMID:26085147
Association analysis of -416 G>C polymorphism of T-cell immunoglobulin and mucin domain-1 gene with asthma in Iran., PMID:26041148
Kidney injury molecule-1 is involved in the chemotactic migration of mesenchymal stem cells., PMID:24652046
Soluble T cell immunoglobulin and mucin domain (TIM)-1 and -4 generated by A Disintegrin And Metalloprotease (ADAM)-10 and -17 bind to phosphatidylserine., PMID:24286866
Kidney injury molecule-1 expression is closely associated with renal allograft damage., PMID:23988168
Reduced numbers of regulatory B cells are negatively correlated with disease activity in patients with new-onset rheumatoid arthritis., PMID:23949637
urinary biomarkers in relapsing antineutrophil cytoplasmic antibody-associated vasculitis., PMID:23547217
The T-cell immunoglobulin and mucin domain (Tim) gene family in asthma, allergy, and autoimmunity., PMID:23406933
TIM family proteins promote the lysosomal degradation of the nuclear receptor NUR77., PMID:23233528
Chronic renal allograft damage after transplantation: what are the reasons, what can we do?, PMID:23080067
A new development of FG-CC' siRNA blocking interaction of Tim-1 and Tim-4 can enhance DC vaccine against gastric cancer ., PMID:22709877
Interactions of human T cell immunoglobin mucins with apoptotic cells., PMID:22282238
Effect of frozen storage on urinary concentration of kidney damage markers., PMID:22206741
T cell immunoglobulin and mucin-domain containing molecule 1 in peripheral blood mononuclear cells in Henoch Schonlein purpura., PMID:22080624
Suppression of allograft rejection by Tim-1-Fc through cross-linking with a novel Tim-1 binding partner on T cells., PMID:21750723
T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus., PMID:21536871
HAVcR-1 reduces the integrity of human endothelial tight junctions., PMID:21378325
Antagonism of TIM-1 blocks the development of disease in a humanized mouse model of allergic asthma., PMID:20628202
Association analysis of TIM-1 -232G > A and 5383_5397 insertion/deletion polymorphisms with childhood asthma and total serum immunoglobulin E levels in middle China., PMID:19476019
TIM-1: a new player in transplant immunity., PMID:19424017
For research use only. Not for human or drug use.
