Catalog No.
PHG67901
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human RUNX2 (Val219-Val404).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
AML3,OSF2,RUNX2,Core-binding factor subunit alpha-1,PEA2-alpha A,CBF-alpha-1,Osteoblast-specific transcription factor 2,Oncogene AML-3,CBFA1,Runt-related transcription factor 2,PEBP2A,OSF-2,SL3-3 enhancer factor 1 alpha A subunit,PEBP2-alpha A,Acute myeloid leukemia 3 protein,Polyomavirus enhancer-binding protein 2 alpha A subunit,SL3/AKV core-binding factor alpha A subunit
Purification
Purified by antigen affinity column.
Accession
Q13950
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Experimental investigation of the effects of allantoin on mandibular distraction osteogenesis., PMID:40461339
TSAb inhibits osteogenic differentiation of MC3T3-E1 cells and exacerbates bone loss in Graves' disease mice., PMID:40354515
Adipose-Derived Mesenchymal Stem Cell Osteodifferentiation after Exposure to Beta-Tricalcium Phosphate Bioceramic Granules with 300 to 600 and 600 to 1,000 µm Sizes., PMID:40334681
Comparison of the bone remodeling in the midpalatal suture during maxillary expansion between young and middle-aged mice., PMID:40324615
Multi-lineage transcriptional and cell communication signatures define pathways in individuals at-risk for developing rheumatoid arthritis that initiate and perpetuate disease., PMID:40235495
Influence of surface texture on osteogenic differentiation of dental pulp stem cells: An in vitro study., PMID:40018713
Multi-lineage transcriptional and cell communication signatures define pathways in individuals at-risk for developing rheumatoid arthritis that initiate and perpetuate disease., PMID:39974976
Alterations of bone proteins in medication-related osteonecrosis of the jaw., PMID:39972547
Dental Pulp Stem Cell Conditioned Medium Enhance Osteoblastic Differentiation and Bone Regeneration., PMID:39514179
Reversal of heavy arterial calcification in a rat model of chronic kidney disease using targeted ethylene diamine tetraacetic acid-loaded albumin nanoparticles., PMID:39263487
Selective inhibition of interleukin 6 receptor decreased inflammatory cytokines and increased proteases in an experimental model of critical calvarial defect., PMID:39166608
Bioactive nanocomposite hydrogel enhances postoperative immunotherapy and bone reconstruction for osteosarcoma treatment., PMID:39079462
Nanoquantification of RUNX2 by a 1,1'-carbonyldiimidazole-diamond mediated sandwich assay for osteogenic differentiation., PMID:38868000
Remote Activation of Mechanotransduction via Integrin Alpha-5 via Aptamer-Conjugated Magnetic Nanoparticles Promotes Osteogenesis., PMID:38258032
A modified animal-free serum technique for efficient isolation and proliferation of mesenchymal stem cells from Hoffa fat pad., PMID:38158693
DLL4/Notch blockade disrupts mandibular advancement-induced condylar osteogenesis by inhibiting H-type angiogenesis., PMID:38100236
Carbonate apatite increases gene expression of osterix and bone morphogenetic protein 2 in the alveolar ridge after socket grafting., PMID:38008425
1,25-Dihydroxyvitamin D3: A Positive Factor for the Osteogenic Differentiation of hPDLSCs and for the Tissue Regenerative Activity of Cell Sheets., PMID:37798942
Atp6i deficient mouse model uncovers transforming growth factor-β1 /Smad2/3 as a key signaling pathway regulating odontoblast differentiation and tooth root formation., PMID:37599332
Investigation of osteogenesis and angiogenesis in perfusion bioreactors using improved multi-layer PCL-nHA-nZnO electrospun scaffolds., PMID:37439932
IL-17A induces valvular endothelial inflammation and aggravates calcific aortic valve disease., PMID:37354607
Enhancement of bone regeneration by coadministration of angiogenic and osteogenic factors using messenger RNA., PMID:37340499
Epigenomic landscape exhibits interferon signaling suppression in the patient of myocarditis after BNT162b2 vaccination., PMID:37264110
The calcium channel Orai1 is required for osteoblast development: Studies in a chimeric mouse with variable in vivo Runx-cre deletion of Orai-1., PMID:37167218
Histochemical assessment of osteoclast-like giant cells in Rankl-/- mice., PMID:37088151
Biological activity of a chitosan-carboxymethylcellulose-zinc oxide and calcium carbonate in 3D scaffolds stabilized by physical links for bone tissue engineering., PMID:37025081
[The role of semaphorin 4D in the mechanism of bisphosphonate-related osteonecrosis of the jaw in rats]., PMID:36970799
Indoxyl-sulfate activation of the AhR- NF-κB pathway promotes interleukin-6 secretion and the subsequent osteogenic differentiation of human valvular interstitial cells from the aortic valve., PMID:36967106
OP3-4 peptide sustained-release hydrogel inhibits osteoclast formation and promotes vascularization to promote bone regeneration in a rat femoral defect model., PMID:36925715
Effects of Dlx2 overexpression on the genes associated with the maxillary process in the early mouse embryo., PMID:36891149
Prostate cancer cell‑derived spondin 2 boosts osteogenic factor levels in osteoblasts via the PI3K/AKT/mTOR pathway., PMID:36484410
Nogo-A Regulates the Fate of Human Dental Pulp Stem Cells toward Osteogenic, Adipogenic, and Neurogenic Differentiation., PMID:36359811
Sclerostin ablation prevents aortic valve stenosis in mice., PMID:36240434
Myeloid cell-specific ablation of Runx2 gene exacerbates post-infarct cardiac remodeling., PMID:36198906
microRNA Expression Profile of Purified Alveolar Epithelial Type II Cells., PMID:36011331
Mechanical Stretch Induced Osteogenesis on Human Annulus Fibrosus Cells through Upregulation of BMP-2/6 Heterodimer and Activation of P38 and SMAD1/5/8 Signaling Pathways., PMID:36010676
HOXC10 intronic duplication is associated with unsealed skull and crest in crested chicken with cerebral hernia., PMID:35905851
Total flavonoids of Rhizoma Drynariae enhances CD31hiEmcnhi vessel formation and subsequent bone regeneration in rat models of distraction osteogenesis by activating PDGF‑BB/VEGF/RUNX2/OSX signaling axis., PMID:35795995
Melatonin Inhibits NF-κB/CREB/Runx2 Signaling and Alleviates Aortic Valve Calcification., PMID:35795373
Abaloparatide Improves Rotator Cuff Healing via Anabolic Effects on Bone Remodeling in a Chronic Rotator Cuff Tear Model of Rat With Osteoporosis: A Comparison With Denosumab., PMID:35404150
Pathological differences in the bone healing processes between tooth extraction socket and femoral fracture., PMID:35372643
Improvement of Lipotoxicity-Induced Islet β Cellular Insulin Secretion Disorder by Osteocalcin., PMID:35313683
The use of alkaline phosphatase and runx2 to distinguish osteosarcoma from other common malignant primary bone tumors in dogs., PMID:35253545
Precision-engineered niche for directed differentiation of MSCs to lineage-restricted mineralized tissues., PMID:35237403
p53 deficiency promotes bone regeneration by functional regulation of mesenchymal stromal cells and osteoblasts., PMID:35195777
KLF4, negatively regulated by miR-7, suppresses osteoarthritis development via activating TGF-β1 signaling., PMID:34891002
Migratory chondroprogenitors retain superior intrinsic chondrogenic potential for regenerative cartilage repair as compared to human fibronectin derived chondroprogenitors., PMID:34880351
Interleukin-1 Is Overexpressed in Injured Muscles Following Spinal Cord Injury and Promotes Neurogenic Heterotopic Ossification., PMID:34841579
Local Renin-Angiotensin System Signaling Mediates Cellular Function of Aortic Valves., PMID:34704164
Identification of GPC3 mutation and upregulation in a multidrug resistant osteosarcoma and its spheroids as therapeutic target., PMID:34611509
For research use only. Not for human or drug use.
