Catalog No.
PHG39701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human LpPLA2/PLA2G7/PAF-AH (Met33-Asn441).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Platelet-activating factor acetylhydrolase,PAFAH,PAF 2-acylhydrolase,PAF acetylhydrolase,2-acetyl-1-alkylglycerophosphocholine esterase,1-alkyl-2-acetylglycerophosphocholine esterase,LDL-PLA(2),LDL-associated phospholipase A2,PLA2G7,Group-VIIA phospholipase A2,gVIIA-PLA2
Purification
Purified by antigen affinity column.
Accession
Q13093
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Black palladium nanoparticle-based lateral flow immunoassay for cardiovascular disease diagnosis., PMID:40365198
Propolis Reduces Inflammation and Dyslipidemia Caused by High-Cholesterol Diet in Mice by Lowering ADAM10/17 Activities., PMID:38931216
Novel Electrochemiluminescent Immunosensor Using Dual Amplified Signals from a CoFe Prussian Blue Analogue and Au Nanoparticle for the Detection of Lp-PLA2., PMID:37432366
Limited Proteolysis-Mass Spectrometry Reveals Aging-Associated Changes in Cerebrospinal Fluid Protein Abundances and Structures., PMID:36741774
A retrospective study of immunoglobulin E as a biomarker for the diagnosis of acute ischemic stroke with carotid atherosclerotic plaques., PMID:36317119
Establishment and clinical application of time-resolved immunofluorescence assay of lipoprotein-associated phospholipase A2., PMID:35351395
Lipid Receptor G2A-Mediated Signal Pathway Plays a Critical Role in Inflammatory Response by Promoting Classical Macrophage Activation., PMID:33941654
Au-coated Fe3O4 core-shell nanohybrids with photothermal activity for point-of-care immunoassay for lipoprotein-associated phospholipase A2 on a digital near-infrared thermometer., PMID:33048173
The selective lipoprotein-associated phospholipase A2 inhibitor darapladib triggers irreversible actions on glioma cell apoptosis and mitochondrial dysfunction., PMID:32668280
[Changes of serum lipoprotein-related phospholipase A2 in patients with white matter lesion based on KIM classification and its correlation with carotid atherosclerotic plaque]., PMID:32311875
ApoCIII-Lp(a) complexes in conjunction with Lp(a)-OxPL predict rapid progression of aortic stenosis., PMID:32054669
Pharmacokinetics and exploratory efficacy biomarkers of bococizumab, an anti-PCSK9 monoclonal antibody, in hypercholesterolemic Japanese subjects
., PMID:31549625
Genetic contributors and soluble mediators in prediction of autoimmune comorbidity., PMID:31444033
[Development and application of monoclonal antibodies anti-human lipoprotein-associated phospholipase A2]., PMID:30912356
Effects of Cervical Rotatory Manipulation (CRM) on Carotid Atherosclerosis Plaque in Vulnerability: A Histological and Immunohistochemical Study Using Animal Model., PMID:30863777
Novel Antiatherosclerotic Therapies., PMID:30816799
Chemiluminescence immunoassay for sensing lipoprotein-associated phospholipase A2 in cardiovascular risk evaluation., PMID:30414434
Photoelectrochemical immunoassay of lipoprotein-associated phospholipase A2 via plasmon-enhanced energy transfer between gold nanoparticles and CdS QDs/g-C3N4., PMID:30283999
Measurement of Lipoprotein-Associated Phospholipase A2 by Use of 3 Different Methods: Exploration of Discordance between ELISA and Activity Assays., PMID:29321128
Biochemical differences in the mass and activity tests of lipoprotein-associated phospholipase A2 explain the discordance in results between the two assay methods., PMID:28899631
Retinal pathology is associated with increased blood-retina barrier permeability in a diabetic and hypercholesterolaemic pig model: Beneficial effects of the LpPLA2 inhibitor Darapladib., PMID:28301218
Bioactive lysophospholipids generated by hepatic lipase degradation of lipoproteins lead to complement activation via the classical pathway., PMID:25205869
Association between lipoprotein associated phospholipase A2 mass and subclinical coronary and carotid atherosclerosis in Retired National Football League players., PMID:25105582
Oxidatively modified phosphatidylserines on the surface of apoptotic cells are essential phagocytic 'eat-me' signals: cleavage and inhibition of phagocytosis by Lp-PLA2., PMID:24464221
[Influence of intensive hypolipidemic therapy on blood concentration of lipoprotein-associated phospholipase A2 in patients with ischemic heart disease]., PMID:24090379
Influence of obesity and cardiometabolic makers on lipoprotein-associated phospholipase A2 (Lp-PLA2) activity in adolescents: the healthy young cross-sectional study., PMID:23413990
The effect of lipoprotein-associated phospholipase A2 deficiency on pulmonary allergic responses in Aspergillus fumigatus sensitized mice., PMID:23140447
Genetic and environmental regulation of inflammatory CVD biomarkers Lp-PLA2 and IgM anti-PC., PMID:21616491
Lipoprotein phospholipase A2 in patients with isolated coronary artery ectasia., PMID:21207044
Naturally occurring human plasminogen, like genetically related apolipoprotein(a), contains oxidized phosphatidylcholine adducts., PMID:20346413
The influence of pravastatin and atorvastatin on markers of oxidative stress in hypercholesterolemic humans., PMID:18436117
Patients with early rheumatoid arthritis exhibit elevated autoantibody titers against mildly oxidized low-density lipoprotein and exhibit decreased activity of the lipoprotein-associated phospholipase A2., PMID:17326817
Short- and long-term elevation of autoantibody titers against oxidized LDL in patients with acute coronary syndromes. Role of the lipoprotein-associated phospholipase A2 and the effect of atorvastatin treatment., PMID:17140582
Lipoprotein-associated phospholipase A2 protein expression in the natural progression of human coronary atherosclerosis., PMID:16960105
Autoantibody titers against OxLDL are correlated with Achilles tendon thickness in patients with familial hypercholesterolemia., PMID:16888320
Lipoprotein-associated phospholipase A(2), platelet-activating factor acetylhydrolase: a potential new risk factor for coronary artery disease., PMID:10856534
For research use only. Not for human or drug use.
