Catalog No.
PHF13501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CCL18/PARC/MIP-4 (Ala21-Ala89).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
PARC,AMAC1,DC-CK1,MIP4,CC chemokine PARC,Pulmonary and activation-regulated chemokine,DCCK1,Alternative macrophage activation-associated CC chemokine 1,MIP-4,Macrophage inflammatory protein 4,Small-inducible cytokine A18,Dendritic cell chemokine 1,C-C motif chemokine 18,CCL18,SCYA18,AMAC-1
Purification
Purified by antigen affinity column.
Accession
P55774
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Blocking of IL-4/IL-13 Signalling With Dupilumab Results in Restoration of Serum and Cutaneous Abnormalities in Netherton Syndrome., PMID:40344324
Real-World Efficacy and Safety of Abrocitinib in Chinese Atopic Dermatitis Patients: A Single-Center Prospective Study., PMID:39927851
Tralokinumab Treatment in Adult Atopic Dermatitis Patients: 28-Week Evaluation of Clinical Effectiveness, Safety, Serum Proteins and Total IgE Levels., PMID:39673366
Serum inflammatory biomarkers associated with disease severity and response to dupilumab treatment in bullous pemphigoid: A cluster analysis., PMID:39358056
Lactate activates CCL18 expression via H3K18 lactylation in macrophages to promote tumorigenesis of ovarian cancer., PMID:39010846
MMP9 and CCL18 associate with chronic urticaria while type I, IV, and VI collagens change with omalizumab treatment., PMID:38953463
IL20Rb aggravates pulmonary fibrosis through enhancing bone marrow derived profibrotic macrophage activation., PMID:38583686
Dupilumab-associated head and neck dermatitis shows a pronounced type 22 immune signature mediated by oligoclonally expanded T cells., PMID:38565563
Clinical characteristics and immune profiles of patients with immune-mediated alopecia associated with COVID-19 vaccinations., PMID:37586672
Role of interleukin-36γ induced by ultraviolet radiation in chronic actinic dermatitis., PMID:37545106
Pulmonary Sarcoidosis: Experimental Models and Perspectives of Molecular Diagnostics Using Quantum Dots., PMID:37511027
The Identification and Clinical Value Evaluation of CYCS Related to Asthma through Bioinformatics Analysis and Functional Experiments., PMID:37091894
Adipose tissue specific CCL18 associates with cardiometabolic diseases in non-obese individuals implicating CD4+ T cells., PMID:37046242
CCL18 signaling from tumor-associated macrophages activates fibroblasts to adopt a chemoresistance-inducing phenotype., PMID:36418470
Biomarkers in asthma in the context of atopic dermatitis in young children., PMID:35871461
IL6 and CCL18 Mediate Cross-talk between VHL-Deficient Kidney Cells and Macrophages during Development of Renal Cell Carcinoma., PMID:35666812
Onchocerca volvulus-specific antibody and cellular responses in onchocerciasis patients treated annually with ivermectin for 30 years and exposed to parasite transmission in central Togo., PMID:35503786
Echinococcus multilocularis specific antibody, systemic cytokine, and chemokine levels, as well as antigen-specific cellular responses in patients with progressive, stable, and cured alveolar echinococcosis: A 10-year follow-up., PMID:35108275
A combined biomarker panel shows improved sensitivity and specificity for detection of ovarian cancer., PMID:34995016
Transcriptomic Profiling of Tape-Strips From Moderate to Severe Atopic Dermatitis Patients Treated With Dupilumab., PMID:34405829
Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis., PMID:34404786
Pathogenic roles and therapeutic potential of the CCL8-CCR8 axis in a murine model of IgG4-related sialadenitis., PMID:34391459
Childhood CCL18, CXCL10 and CXCL11 levels differentially relate to and predict allergy development., PMID:34101271
Malignant Phyllodes of Breast., PMID:33983602
Biomarkers in atopic dermatitis-a review on behalf of the International Eczema Council., PMID:33516871
Tumor Cell-Secreted ISG15 Promotes Tumor Cell Migration and Immune Suppression by Inducing the Macrophage M2-Like Phenotype., PMID:33424843
BIOMARKERS OF DISEASE ACTIVITY IN SYSTEMIC SCLEROSIS., PMID:33310967
Osteopontin Links Myeloid Activation and Disease Progression in Systemic Sclerosis., PMID:33294861
Immunoglobulin G of systemic sclerosis patients programs a pro-inflammatory and profibrotic phenotype in monocyte-like THP-1 cells., PMID:33230552
Exploration of biomarkers to predict clinical improvement of atopic dermatitis in patients treated with dupilumab: A study protocol., PMID:32957324
Chip-based serum proteomics approach to reveal the potential protein markers in the sub-acute stroke patients receiving the treatment of Ginkgo Diterpene Lactone Meglumine Injection., PMID:32413576
Comparative analysis of inflammatory signature profiles in eosinophilic and noneosinophilic chronic rhinosinusitis with nasal polyposis., PMID:32039442
Surfactant protein D is associated with 3-month mortality of anti-MDA5 antibody-interstitial lung disease., PMID:31994487
Reverse transcriptase multiplex ligation-dependent probe amplification in endomyocardial biopsies for the diagnosis of cardiac allograft rejection., PMID:31822443
Serum levels of inflammation-related markers and metabolites predict response to neoadjuvant chemotherapy with and without bevacizumab in breast cancers., PMID:31444972
Pathogenesis of IgG4-related disease. Comparison with Sjögren's syndrome., PMID:31425659
Biomarkers in IgG4-related disease: A systematic review., PMID:31280934
Intrapulmonary Autoantibodies to HSP72 Are Associated with Improved Outcomes in IPF., PMID:31098385
Gremlin, A Potential Urinary Biomarker of Anca-Associated Crescentic Glomerulonephritis., PMID:31053735
CCL18 secreted from M2 macrophages promotes migration and invasion via the PI3K/Akt pathway in gallbladder cancer., PMID:30276551
Interstitial lung disease in Systemic sclerosis: insights into pathogenesis and evolving therapies., PMID:32185315
Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis., PMID:30194992
Tumor-associated macrophages derived CCL18 promotes metastasis in squamous cell carcinoma of the head and neck., PMID:30181713
Baseline IL-22 expression in patients with atopic dermatitis stratifies tissue responses to fezakinumab., PMID:30121291
Significance of molecular biomarkers in idiopathic pulmonary fibrosis: A mini review., PMID:30030108
High Index Values of Enzyme-Linked Immunosorbent Assay for BP180 at Baseline Predict Relapse in Patients With Bullous Pemphigoid., PMID:29868591
The homeodomain transcription factor MEIS1 triggers chemokine expression and is involved in CD8+ T-lymphocyte infiltration in early stage ovarian cancer., PMID:29802738
An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium., PMID:28648867
Tumor-Associated Macrophages Promote Malignant Progression of Breast Phyllodes Tumors by Inducing Myofibroblast Differentiation., PMID:28512246
[Clinical validation of multiple biomarkers suspension array technology for ovarian cancer]., PMID:28190310
For research use only. Not for human or drug use.
