Anti-CD178/FASLG/TNFSF6 Polyclonal Antibody

Catalog No.

PHE54301

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD178/FASLG/TNFSF6 (Gln103-Leu281).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Receptor-binding FasL ectodomain,APL,APT1LG1,FasL ICD,Fas antigen ligand,CD178,sFasL,CD95L,APTL,TNFSF6,Apoptosis antigen ligand,SPA,FASLG,FasL,SPPL2A-processed FasL form,Tumor necrosis factor ligand superfamily member 6,Soluble Fas ligand,Fas ligand,CD95 ligand,CD95-L,FASL

Purification

Purified by antigen affinity column.

Accession

P48023

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

A Novel Tetravalent CD95/Fas Fusion Protein With Superior CD95L/FasL Antagonism., PMID:39219154

Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies., PMID:35013338

CAR-NK Cells: From Natural Basis to Design for Kill., PMID:34970253

Immune response to intravenous immunoglobulin in patients with Kawasaki disease and MIS-C., PMID:34464357

Cord blood soluble Fas ligand linked to allergic rhinitis and lung function in seven-year-old children., PMID:33879403

Glycolysis and Oxidative Phosphorylation Play Critical Roles in Natural Killer Cell Receptor-Mediated Natural Killer Cell Functions., PMID:32153568

Effects of 5-FU and anti-EGFR antibody in combination with ASA on the spherical culture system of HCT116 and HT29 colorectal cancer cell lines., PMID:31180528

Killing of Latently HIV-Infected CD4 T Cells by Autologous CD8 T Cells Is Modulated by Nef., PMID:30254642

ADAM15 in Apoptosis Resistance of Synovial Fibroblasts: Converting Fas/CD95 Death Signals Into the Activation of Prosurvival Pathways by Calmodulin Recruitment., PMID:30003689

Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation., PMID:29889098

Early activation of CD95 is limited and localized to the cytotoxic synapse., PMID:29797791

Fas/FasL interaction mediates imbalanced cytokine/cytotoxicity responses of iNKT cells against Jurkat cells., PMID:29783159

Curcumin enhances the anti-cancer effects of Paris Saponin II in lung cancer cells., PMID:29608021

Magnetic nanoparticle-mediated gene therapy to induce Fas apoptosis pathway in breast cancer., PMID:29593359

Inhibition of CD95/CD95L (FAS/FASLG) Signaling with APG101 Prevents Invasion and Enhances Radiation Therapy for Glioblastoma., PMID:29453321

Induction of apoptosis in breast cancer cells in vitro by Fas ligand reverse signaling., PMID:29185091

Immunohistochemical Analysis of the Extrinsic Apoptosis Process in the Non-Neoplastic and Neoplastic Prostate., PMID:28984341

Genetic polymorphisms predict response to anti-tumor necrosis factor treatment in Crohn's disease., PMID:28785150

FasR and FasL in colorectal cancer., PMID:28766682

DcR3 promotes hepatoma cell migration by downregulating E-cadherin expression., PMID:28560426

Lithium enhances the antitumour effect of temozolomide against TP53 wild-type glioblastoma cells via NFAT1/FasL signalling., PMID:28359080

B-cells with a FasL expressing regulatory phenotype are induced following successful anti-tuberculosis treatment., PMID:28250925

Review of Toxic Epidermal Necrolysis., PMID:27999358

Rituximab response in follicular lymphoma is associated with the rs20575 polymorphism in TRAILR1 extrinsic apoptosis trigger., PMID:27977511

Regulation of Intrinsic and Extrinsic Apoptotic Pathways in Osteosarcoma Cells Following Oleandrin Treatment., PMID:27886059

Bifidobacterial recombinant thymidine kinase-ganciclovir gene therapy system induces FasL and TNFR2 mediated antitumor apoptosis in solid tumors., PMID:27464624

A polymorphism in FASL is associated with rituximab response in follicular lymphoma patients., PMID:26950187

T lymphocytes engineered to express a CD16-chimeric antigen receptor redirect T-cell immune responses against immunoglobulin G-opsonized target cells., PMID:26705740

RANKL/RANK interaction promotes the growth of cervical cancer cells by strengthening the dialogue between cervical cancer cells and regulation of IL-8 secretion., PMID:26398902

Enhancing the antitumor efficacy of a cell-surface death ligand by covalent membrane display., PMID:25902490

BIN1 tumor suppressor regulates Fas/Fas ligand-mediated apoptosis through c-FLIP in cutaneous T-cell lymphoma., PMID:25578476

Enhancing the bystander killing effect of an oncolytic HSV by arming it with a secretable apoptosis activator., PMID:25567538

Hepatitis B virus core protein inhibits Fas-mediated apoptosis of hepatoma cells via regulation of mFas/FasL and sFas expression., PMID:25466893

Radiation-induced glioblastoma signaling cascade regulates viability, apoptosis and differentiation of neural stem cells (NSC)., PMID:25273222

Immunomodulation due to plasma or plasma-platelet apheresis donation: Events occurring during donation procedures., PMID:25266338

[Natural killer cell cytotoxic activity in critical pediatric patients with suspected hemophagocytic syndrome]., PMID:25081072

Plasmacytoid dendritic cells mediate synergistic effects of HIV and lipopolysaccharide on CD27+ IgD- memory B cell apoptosis., PMID:25056888

CD8+HLA-DR+ T cells are increased in patients with severe aplastic anemia., PMID:24969051

Fas/FasL in the immune pathogenesis of severe aplastic anemia., PMID:24938700

Protection of neuronal cell death against diabetes-induced apoptosis by Fas blocker ZB4., PMID:24874011

Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors., PMID:24793239

Infection with respiratory syncytial virus influences FasL-mediated apoptosis of pulmonary γδ T cells in a murine model of allergen sensitization., PMID:24564286

Role of Fas/FasL pathway-mediated alveolar macrophages releasing inflammatory cytokines in human silicosis., PMID:24331540

Extra cellular matrix derived metabolite regulates angiogenesis by FasL mediated apoptosis., PMID:24324608

Differential protein-protein interactions of full length human FasL and FasL fragments generated by proteolysis., PMID:24291222

Epstein-Barr Virus_Encoded LMP1 upregulates microRNA-21 to promote the resistance of nasopharyngeal carcinoma cells to cisplatin-induced Apoptosis by suppressing PDCD4 and Fas-L., PMID:24194922

CD80 (B7.1) and CD86 (B7.2) induce EBV-transformed B cell apoptosis through the Fas/FasL pathway., PMID:24008628

CD95 (FAS) and CD178 (FASL) induce the apoptosis of CD4+ and CD8+ cells isolated from the peripheral blood and spleen of dogs naturally infected with Leishmania spp., PMID:23920055

[Pro-apoptotic effects of curcumin associated with CIK cells against ovarian carcinoma cells]., PMID:23660215

[Apoptosis of human umbilical vein endothelial cells induced by IgA1 isolated from Henoch-Schönlein purpura patients]., PMID:23527930

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