Catalog No.
PHE44001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD158i/KIR2DS4 (Gln22-Ser302).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
P58 natural killer cell receptor clones CL-39/CL-17,CD158i,MHC class I NK cell receptor,CD158I,p58 NK receptor CL-39/CL-17,NKAT8,KKA3,NKAT-8,CD158 antigen-like family member I,Killer cell immunoglobulin-like receptor 2DS4,Natural killer-associated transcript 8,KIR2DS4
Purification
Purified by antigen affinity column.
Accession
P43632
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
HLA-DPB1*13:01 associates with enhanced, and KIR2DS4*001 with diminished protection from developing severe COVID-19., PMID:37850268
Activating killer cell immunoglobulin-like receptors: Detection, function and therapeutic use., PMID:31755661
Combination of KIR2DS4 and FcγRIIa polymorphisms predicts the response to cetuximab in KRAS mutant metastatic colorectal cancer., PMID:30796344
A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation., PMID:30679439
Identification of a Natural Killer Cell Receptor Allele That Prolongs Survival of Cytomegalovirus-Positive Glioblastoma Patients., PMID:27406829
Detection and significance of cytotoxic cell subsets in biopsies of HCV-infected human livers., PMID:24232187
A comprehensive analysis of the binding of anti-KIR antibodies to activating KIRs., PMID:24173145
Alterations in NK cell phenotype in relation to liver steatosis in children with chronic hepatitis C., PMID:23558709
CD158k/KIR3DL2 is a useful marker for identifying neoplastic T-cells in Sézary syndrome by flow cytometry., PMID:18061949
T-cell large granular lymphocyte leukemias have multiple phenotypic abnormalities involving pan-T-cell antigens and receptors for MHC molecules., PMID:16416744
MHC class I-independent recognition of NK-activating receptor KIR2DS4., PMID:15265913
A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation., PMID:8765026
For research use only. Not for human or drug use.
