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Anti-CCL4/MIP-1-beta Polyclonal Antibody

Catalog #:   PHC96901 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P13236
Overview

Catalog No.

PHC96901

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CCL4/MIP-1-beta (Ala24-Asn92).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

MIP-1-beta(1-69),MIP-1-beta,C-C motif chemokine 4,Protein H400,ACT-2,HC21,T-cell activation protein 2,Lymphocyte activation gene 1 protein,LAG-1,SIS-gamma,Small-inducible cytokine A4,G-26 T-lymphocyte-secreted protein,Macrophage inflammatory protein 1-beta,LAG1,PAT 744,CCL4,SCYA4,MIP1B

Purification

Purified by antigen affinity column.

Accession

P13236

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CCL4/MIP-1-beta antibody (PHC96901) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 35 kDa
    Observed MW: 35 kDa
References

Lack of pathogenic involvement of CCL4 and its receptor CCR5 in arthritogenic alphavirus disease., PMID:40468739

Harnessing local and system immune profiling delineating differential responders to first-line sintilimab (anti-PD-1 antibody) combined with chemotherapy in extensive-stage small cell lung cancer: an exploratory biomarker analysis of a phase II study., PMID:40404633

IL1RAP Expression in Human Atherosclerosis: A Target of Novel Antibodies to Reduce Vascular Inflammation and Adhesion., PMID:40371594

Correlation among ocular surface changes and systemic hematologic indexes and disease activity in primary Sjögren's syndrome: a cross-sectional study., PMID:40329232

Type I IFN receptor blockade alleviates liver fibrosis through macrophage-derived STAT3 signaling., PMID:40260261

Oligodendroglial precursor cells modulate immune response and early demyelination in a murine model of multiple sclerosis., PMID:40173259

Comparison of Immune and Systemic Inflammation Parameters in Patients with a Depressive Episode in Bipolar Disorder and Major Depressive Disorder: A Scoping Review., PMID:39980624

Identification of novel autoantibodies in Sjögren's disease., PMID:39963128

Sequential transcriptome profiling: comparative analysis of normal and canine lymphoma preceding detailed T-cell and B-cell subtype comparison., PMID:39911484

Interferon-γ production in response to the cytotoxic T lymphocyte epitope within an antigen incorporated in simian virus 40 virus-like particles., PMID:39897799

Upregulation of interferon-γ response genes in monocytes and T cells identified by single-cell transcriptomics in patients with anti-citrullinated peptide antibody-positive early rheumatoid arthritis., PMID:39877346

Liver oval cells in response to HDAC1 inhibitor trichostatin A: immunohistochemical characterization using OV-6 hepatic expression., PMID:39809587

CCL4 Affects Eosinophil Survival via the Shedding of the MUC1 N-Terminal Domain in Airway Inflammation., PMID:39791734

Tumor β-Catenin Expression Associated With Poor Prognosis to Anti-PD-1 Antibody Monotherapy in Non-small Cell Lung Cancer., PMID:39758230

Osteopontin neutralization increases vitamin D receptors on NKT cells and ameliorates liver fibrosis by promoting their activity., PMID:39654627

The FGFR inhibitor Rogaratinib reduces microglia reactivity and synaptic loss in TBI., PMID:39635532

Human single cell RNA-sequencing reveals a targetable CD8+ exhausted T cell population that maintains mouse low-grade glioma growth., PMID:39609412

A Phase II Open-Label, Randomized Clinical Trial of Atezolizumab with or without Human Recombinant IL-7 (CYT107) in Advanced Urothelial Cancer., PMID:39576210

Double-Negative T Cells Promote Liver Fibrosis Progression by Regulating Treg/Th17., PMID:39575557

ACBP/DBI neutralization for the experimental treatment of fatty liver disease., PMID:39550516

A self-amplifying RNA RSV prefusion-F vaccine elicits potent immunity in pre-exposed and naïve non-human primates., PMID:39543172

Major alteration of lung microbiome and the host responses in critically ill COVID-19 patients with high viral load., PMID:39532981

Modulation of Notch signaling pathway in activated hepatic stellate cells does not ameliorate the outcome of liver fibrosis in carbon tetrachloride and DDC-feeding models., PMID:39529885

Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy., PMID:39515328

Inhibition of Bruton's tyrosine kinase with PD-1 blockade modulates T cell activation in solid tumors., PMID:39513363

Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing., PMID:39483478

OPN-Mediated Crosstalk Between Hepatocyte E4BP4 and Hepatic Stellate Cells Promotes MASH-Associated Liver Fibrosis., PMID:39473081

42-parameter mass cytometry panel to assess cellular and functional phenotypes of leukocytes in bronchoalveolar lavage of Rhesus macaque., PMID:39386621

Transferrin receptor-targeted immunostimulant for photodynamic immunotherapy against metastatic tumors through β-catenin/CREB interruption., PMID:39309507

Targeted proteomics of cerebrospinal fluid in treatment naïve multiple sclerosis patients identifies immune biomarkers of clinical phenotypes., PMID:39294186

Lack of pathogenic involvement of CCL4 and its receptor CCR5 in arthritogenic alphavirus disease., PMID:39131287

Regulatory B Cells Expressing Granzyme B from Tolerant Renal Transplant Patients: Highly Differentiated B Cells with a Unique Pathway with a Specific Regulatory Profile and Strong Interactions with Immune System Cells., PMID:39120317

Selection for high and low antibody responses to sheep red blood cells influences cytokine and chemokine expression in chicken peripheral blood leukocytes and splenic tissue., PMID:38936074

Rabies Virus Infection Causes Pyroptosis of Neuronal Cells., PMID:38891803

Race-Related Differences in Sipuleucel-T Response among Men with Metastatic Castrate-Resistant Prostate Cancer., PMID:38856749

CCL4 contributes to aging related angiogenic insufficiency through activating oxidative stress and endothelial inflammation., PMID:38739303

Persistent differences in the immunogenicity of the two COVID-19 primary vaccines series, modulated by booster mRNA vaccination and breakthrough infection., PMID:38729909

HIV/HBV coinfection remodels the immune landscape and natural killer cell ADCC functional responses., PMID:38687604

Immunotherapy with an antibody against CD1d modulates neuroinflammation in an α-synuclein transgenic model of Lewy body like disease., PMID:38622654

Chemokine expression in sera of patients with microscopic polyangiitis and granulomatosis with polyangiitis., PMID:38622321

Major alteration of Lung Microbiome and the Host Reaction in critically ill COVID-19 Patients with high viral load., PMID:38496464

CCR5/CXCR3 antagonist TAK-779 prevents diffuse alveolar damage of the lung in the murine model of the acute respiratory distress syndrome., PMID:38449806

Serum levels of CXCL5 are decreased and correlate with circulating platelet counts in systemic lupus erythematosus., PMID:38439196

Relationship between serum IgA levels and low percentage forced expiratory volume in the first second in asthma., PMID:38376485

Delayed CCL23 response is associated with poor outcomes after cardiac arrest., PMID:38325139

The Immune Signature of CSF in Multiple Sclerosis with and without Oligoclonal Bands: A Machine Learning Approach to Proximity Extension Assay Analysis., PMID:38203309

Hydroxychloroquine ameliorates immune functionality and intestinal flora disorders of IgA nephropathy by inhibition of C1GALT1/Cosmc pathway., PMID:38151955

Analysis of Changes in Plasma Cytokine Levels in Response to IL12 Therapy in Three Clinical Trials., PMID:38108458

Rapid transient and longer-lasting innate cytokine changes associated with adaptive immunity after repeated SARS-CoV-2 BNT162b2 mRNA vaccinations., PMID:38090597

Antibody response and soluble mediator profile in the first six months following acute SARS-CoV-2 infection., PMID:37903875

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-CCL4/MIP-1-beta Polyclonal Antibody [PHC96901]
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