Catalog No.
PHC01701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PPBP/CXCL7/NAP-2 (Ala59-Asp128).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
NAP-2,NAP-2(1-63),NAP-2(73),PPBP,CXCL7,PBP,Small-inducible cytokine B7,Macrophage-derived growth factor,LA-PF4,Leukocyte-derived growth factor,CTAP-III,CTAP-III(1-81),Low-affinity platelet factor IV,TGB1,Beta-TG,C-X-C motif chemokine 7,MDGF,Platelet basic protein,LDGF,NAP-2(74),THBGB1,NAP-2(1-66),CTAP3,SCYB7
Purification
Purified by antigen affinity column.
Accession
P02775
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
The Platelet-Specific Gene Signature in the Immunoglobulin G4-Related Disease Transcriptome., PMID:39859144
Proteomic Analysis of Human Chylomicron Remnants Isolated by Apolipoprotein B-48 Immunoprecipitation., PMID:39085140
Development of protein-polymer conjugate nanoparticles for modulation of dendritic cell phenotype and antigen-specific CD4 T cell responses., PMID:38911349
CXCL7 aggravates the pathological manifestations of neuromyelitis optica spectrum disorder by enhancing the inflammatory infiltration of neutrophils, macrophages and microglia., PMID:36184052
Monocytes secrete CXCL7 to promote breast cancer progression., PMID:34789744
Simultaneous determination of CXCL7 chemokine and MMP3 metalloproteinase as biomarkers for rheumatoid arthritis., PMID:34364500
Increased CCL24 and CXCL7 levels in the cerebrospinal fluid of patients with neurosyphilis., PMID:32419252
Increased Plasma Levels of Platelet Factor 4 and β-thromboglobulin in Women with Recurrent Pregnancy Loss., PMID:32341585
ADP secreted by dying melanoma cells mediates chemotaxis and chemokine secretion of macrophages via the purinergic receptor P2Y12., PMID:31591378
Platelet Microparticles Mediate Glomerular Endothelial Injury in Early Diabetic Nephropathy., PMID:30341150
Ubiquitin-dependent proteolysis of CXCL7 leads to posterior longitudinal ligament ossification., PMID:29782494
CXCL7 is a predictive marker of sunitinib efficacy in clear cell renal cell carcinomas., PMID:28850564
PPBP and DEFA1/DEFA3 genes in hyperlipidaemia as feasible synergistic inflammatory biomarkers for coronary heart disease., PMID:28420383
Effect of platelet-derived β-thromboglobulins on coagulation., PMID:28384443
Plasma-derived Extracellular Vesicles Contain Predictive Biomarkers and Potential Therapeutic Targets for Myocardial Ischemic (MI) Injury., PMID:27234505
NAP-2 Secreted by Human NK Cells Can Stimulate Mesenchymal Stem/Stromal Cell Recruitment., PMID:27052313
Elevated expression of platelet-derived chemokines in patients with antiphospholipid syndrome., PMID:26283469
Increased expression of angiogenic and inflammatory proteins in the vitreous of patients with ischemic central retinal vein occlusion., PMID:25978399
Expression of chemokines CXCL4 and CXCL7 by synovial macrophages defines an early stage of rheumatoid arthritis., PMID:25858640
Circulating platelet-neutrophil aggregates play a significant role in Kawasaki disease., PMID:25787672
The CXCL7/CXCR1/2 axis is a key driver in the growth of clear cell renal cell carcinoma., PMID:24335961
The σ 1 receptor agonist 4-PPBP elicits ERK1/2 phosphorylation in primary neurons: a possible mechanism of neuroprotective action., PMID:20538010
Increased invasion through basement membrane by CXCL7-transfected breast cells., PMID:18954601
Proteomic analysis of factors released from p21-overexpressing tumour cells., PMID:16739131
Chlamydophila pneumoniae and human cytomegalovirus in atherosclerotic carotid plaques--combined presence and possible interactions., PMID:16696549
Myofibroblast matrix metalloproteinases activate the neutrophil chemoattractant CXCL7 from intestinal epithelial cells., PMID:16401476
Induction and antimicrobial activity of platelet basic protein derivatives in human monocytes., PMID:15316029
[Heparin-induced thrombopenia]., PMID:12555357
Platelet factor 4 induces human natural killer cells to synthesize and release interleukin-8., PMID:12223528
Platelet microbicidal activity is an important defense factor against viridans streptococcal endocarditis., PMID:11494165
Defining an antigenic epitope on platelet factor 4 associated with heparin-induced thrombocytopenia., PMID:9787161
Quantitative comparison of C-X-C chemokines produced by endotoxin-stimulated human alveolar macrophages., PMID:9688939
Differences in specificity of heparin-dependent antibodies developed in heparin-induced thrombocytopenia and consequences on cross-reactivity with danaparoid sodium., PMID:9375738
The CXC-chemokine neutrophil-activating peptide-2 induces two distinct optima of neutrophil chemotaxis by differential interaction with interleukin-8 receptors CXCR-1 and CXCR-2., PMID:9373270
Activation of the megakaryocyte-specific gene platelet basic protein (PBP) by the Ets family factor PU.1., PMID:9334192
Thrombin-activated human platelets release two NAP-2 variants that stimulate polymorphonuclear leukocytes., PMID:8950790
Further characterization of histamine releasing chemokines present in fractionated supernatants derived from human mononuclear cells., PMID:8877158
Presence of autoantibodies to interleukin-8 or neutrophil-activating peptide-2 in patients with heparin-associated thrombocytopenia., PMID:8695787
Platelet-streptococcal interactions in endocarditis., PMID:8909879
Structural requirements of platelet chemokines for neutrophil activation., PMID:7919350
A novel molecular variant of the neutrophil-activating peptide NAP-2 with enhanced biological activity is truncated at the C-terminus: identification by antibodies with defined epitope specificity., PMID:7688853
Regulation of glucose transporters by connective tissue activating peptide-III isoforms., PMID:1527075
Platelet basic protein, low-affinity platelet factor 4, and beta-thromboglobulin: purification and identification., PMID:2523998
For research use only. Not for human or drug use.
