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Research Grade Golimumab

Catalog #:   DHB94404 Specific References (100) DATASHEET
Host species: Human
Isotype: IgG1-kappa
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHB94404

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

TNF, Tumor necrosis factor ligand superfamily member 2, N-terminal fragment, ICD2, NTF, TNF-a, TNF-alpha, Tumor necrosis factor, TNFSF2, TNFA, Cachectin, ICD1

Concentration

1.3mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01375

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

CNTO 148, CAS: 476181-74-5

Clone ID

Golimumab

Data Image
  • Bioactivity
    Detects Human TNFa/TNF-alpha in indirect ELISAs.
  • SDS-PAGE
    SDS PAGE for Golimumab
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Golimumab and Beta-Cell Function in Youth with New-Onset Type 1 Diabetes, PMID: 33207093

[Golimumab], PMID: 23961671

Subcutaneous golimumab induces clinical response and remission in patients with moderate-to-severe ulcerative colitis, PMID: 23735746

Golimumab, PMID: 20065639

Golimumab in the treatment of psoriatic arthritis, PMID: 30221556

Golimumab (anti-TNF monoclonal antibody): where we stand today, PMID: 33369527

Subcutaneous golimumab maintains clinical response in patients with moderate-to-severe ulcerative colitis, PMID: 23770005

Golimumab in inflammatory bowel diseases: present and future scenarios, PMID: 30206776

Golimumab: A Review in Inflammatory Arthritis, PMID: 28530020

Golimumab for the treatment of ulcerative colitis, PMID: 28472597

Golimumab for the treatment of axial spondyloarthritis, PMID: 27817204

Golimumab for rheumatoid arthritis, PMID: 20091667

Golimumab for moderately to severely active ulcerative colitis, PMID: 27498886

Patients with ankylosing spondylitis treatment by golimumab: a systematic review and meta-analysis, PMID: 32447529

Golimumab, a human antibody to tumour necrosis factor {alpha} given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: the GO-FORWARD Study, PMID: 19066176

A review on golimumab in the treatment of psoriatic arthritis, PMID: 28838285

[Golimumab Therapy in Ulcerative Colitis], PMID: 26907481

Golimumab in patients with active rheumatoid arthritis after treatment with tumour necrosis factor alpha inhibitors (GO-AFTER study): a multicentre, randomised, double-blind, placebo-controlled, phase III trial, PMID: 19560810

Golimumab, PMID: 19721444

Golimumab for treatment of axial spondyloarthritis, PMID: 26798943

Efficacy and safety of certolizumab pegol and golimumab in the treatment of non-infectious uveitis, PMID: 30943133

Effectiveness of golimumab in ulcerative colitis: A review of the real world evidence, PMID: 30555013

Efficacy and safety of golimumab in patients with ankylosing spondylitis: results of a randomized, double-blind, placebo-controlled, phase III trial, PMID: 18975305

Golimumab for the treatment of axial spondyloarthritis, PMID: 26523483

GO-DACT: a phase 3b randomised, double-blind, placebo-controlled trial of GOlimumab plus methotrexate (MTX) versus placebo plus MTX in improving DACTylitis in MTX-naive patients with psoriatic arthritis, PMID: 32193187

Golimumab in adolescents with Crohn's disease refractory to previous tumour necrosis factor antibody, PMID: 32781480

Golimumab, the newest TNF-α blocker, comes of age, PMID: 25602858

Golimumab for moderate to severe ulcerative colitis, PMID: 28276288

Golimumab for the treatment of psoriatic arthritis, PMID: 21609657

Golimumab and immunogenicity? 2010 and beyond, PMID: 21612149

Golimumab for rheumatoid arthritis: a systematic review, PMID: 20436075

Intravenous golimumab in rheumatoid arthritis, PMID: 24831189

Golimumab: clinical update on its use for ulcerative colitis, PMID: 25876561

Therapeutic Drug Monitoring of Golimumab in the Treatment of Ulcerative Colitis, PMID: 28374338

Golimumab and malignancies: true or false association?, PMID: 20373059

Golimumab in real-world practice in patients with ulcerative colitis: Twelve-month results, PMID: 32550760

Adverse effects of golimumab in the treatment of rheumatologic diseases, PMID: 23984970

An appraisal of golimumab in the treatment of severe, active nonradiographic axial spondyloarthritis, PMID: 27468228

Evaluation of golimumab for the treatment of patients with active rheumatoid arthritis, PMID: 26811250

Letter: golimumab efficacy in patients with Crohn's disease and concomitant severe arthritis, PMID: 32445531

Golimumab for the treatment of ankylosing spondylitis: a NICE single technology appraisal, PMID: 23580355

Golimumab improves patient-reported outcomes in daily practice of inflammatory rheumatic diseases in Germany, PMID: 32722921

Whither Type 1 Diabetes?, PMID: 33207099

Golimumab therapy of rheumatoid arthritis: an overview, PMID: 20618765

Golimumab: a tumor necrosis factor alpha inhibitor for the treatment of rheumatoid arthritis, PMID: 20118145

Golimumab: in the treatment of rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis, PMID: 19489653

[Clinical analysis of golimumab in the treatment of severe/refractory cardiovascular involvement in Behcet syndrome], PMID: 33331313

Golimumab effectiveness in biologic inadequate responding patients with rheumatoid arthritis, psoriatic arthritis and spondyloarthritis in real-life from the Italian registry GISEA, PMID: 32755721

Why golimumab in the treatment of psoriatic arthritis, ankylosing spondylitis and rheumatoid arthritis?, PMID: 25829189

Golimumab in radiographic and nonradiographic axial spondyloarthritis: a review of clinical trials, PMID: 27445459

Influence of Pharmacokinetic-Pharmacodynamic Failure Mechanisms on Outcomes in Biologic Therapy Sequencing in Inflammatory Bowel Disease: A Retrospective Cohort Study., PMID:40531271

IGF2BP2 regulates inflammation in ulcerative colitis through N6-methyladenosine-dependent modulation of CBR1., PMID:40526983

Efficacy of Golimumab in Early Axial Spondyloarthritis in Relation to Gut Inflammation (GO-GUT), an Early Remission Induction Study., PMID:40524500

Treatment sequences, outcomes, healthcare utilization, and costs in patients with inflammatory bowel diseases requiring advanced treatment-real world comparative effectiveness from German claims data., PMID:40481399

Pharmacogenomics of TNF inhibitors., PMID:40469293

Experience of High Tibial Osteotomy for Patients with Rheumatoid Arthritis Treated with Recent Medication: A Case Series., PMID:40429328

The Relationship Between TNF-α Inhibitor Potency and HBV Reactivation in Patients With Rheumatic Disorders., PMID:40418092

Systematic review and meta-analysis of the efficacy of biologic and targeted synthetic therapies in sarcoidosis., PMID:40393718

Golimumab retention in patients with psoriatic arthritis and axial spondyloarthritis: evidence from up to a decade of follow-up., PMID:40380936

Drug-associated infections and infestations in older adults with tumor necrosis factor-alpha inhibitors: a real-world retrospective and pharmacovigilance study., PMID:40371340

Real-World Insights From Türkiye: Biologic DMARDs Usage in Spondyloarthritis Patients With Chronic Kidney Disease., PMID:40358366

Aggregate Distributional Cost-Effectiveness Analysis of Biologics for the Treatment of Ankylosing Spondylitis in Chile., PMID:40329067

Prevalence of opportunistic infections in Syrian inflammatory bowel disease patients on biologic therapy: a multi-center retrospective cross-sectional study., PMID:40320559

Unveiling the differences: infection disorders associated with tumor necrosis factor α inhibitors in pediatric patients-a pharmacovigilance study (2004-2023)., PMID:40317305

Diffusion dimensionality modeling of subcutaneous/intramuscular absorption of antibodies and long-acting injectables., PMID:40263185

Racial Disparities in Utilization of Medications and Disease Outcomes in Inflammatory Bowel Disease Patients., PMID:40260307

Recommendations for the Use of Disease-Modifying Antirheumatic Drugs in Pregnancy and Reproductive Health for Patients With Rheumatic Disease: A Scoping Review., PMID:40256995

Characterising infusion/injection-related reactions in patients with rheumatoid arthritis treated with biologic agents., PMID:40249052

Relapsing-remitting multiple sclerosis as a potential consequence of thalidomide treatment: A case report., PMID:40245782

Immunotherapy as a treatment for type 1 diabetes mellitus in children and young adults: A comprehensive systematic review and meta-analysis., PMID:40215252

Dual biological treatments in immune-mediated disorders: a single center experience., PMID:40200173

Rapid, Single-Step Monitoring of Monoclonal Antibody Bioavailability by Using a TNF-α-Based Multiepitope DNA Nanoswitch., PMID:40198205

Biosimilars versus biological therapy in inflammatory bowel disease: challenges and targeting strategies using drug delivery systems., PMID:40186719

Infection toxicity assessment of tumor necrosis factor α inhibitors in the treatment of IBD: a real-world study based on the US food and drug administration adverse events reporting system (FAERS)., PMID:40156444

Treatment of uveitis in Blau syndrome: A systematic review and meta-analysis., PMID:40147219

Abatacept, Golimumab, and Sarilumab as Selected Bio-Originator Disease-Modifying Antirheumatic Drugs with Diverse Mechanisms of Action in Their Current Use in Treatment., PMID:40142915

Biological Disease-Modifying Antirheumatic Drugs Decrease Uric Acid Levels in the Sera of Patients with Psoriatic Arthritis., PMID:40136396

Guselkumab versus golimumab in patients with active psoriatic arthritis and inadequate response to an initial tumor necrosis factor inhibitor: study protocol for EVOLUTION, a pragmatic, phase 3b, open-label, randomized, controlled effectiveness trial., PMID:40102973

Effect of TNF-α blockers on reducing the risk of dementia in rheumatoid arthritis: a nationwide cohort study., PMID:40095620

Anti-Rheumatic potential of biological DMARDS and protagonistic role of bio-markers in early detection and management of rheumatoid arthritis., PMID:40091354

Golimumab-induced lichen planus pigmentosus in a patient with ulcerative colitis., PMID:40087062

Risk of hematologic malignancies in psoriasis and rheumatoid arthritis patients using long term TNF-α inhibitors: a retrospective nationwide study., PMID:40055388

Dose Escalation Patterns and Associated Costs of Advanced Therapies for Ulcerative Colitis in France and the United Kingdom: A Retrospective Database Analysis., PMID:40046402

Conducting a real-world study of Tumor Necrosis factor-alpha inhibitors-induced Systemic Lupus Erythematosus based on the FAERS database., PMID:40000785

In vitro Stability Study of a Panel of Commercial Antibodies at Physiological pH and Temperature as a Guide to Screen Biologic Candidate Molecules for the Potential Risk of In vivo Asparagine Deamidation and Activity Loss., PMID:39979532

Comparative Effectiveness and Safety of the JAK Inhibitors and Biologic Disease-Modifying Antirheumatic Drugs in Treating Children With Nonsystemic Juvenile Idiopathic Arthritis: A Bayesian Meta-Analysis of Randomized Controlled Trials., PMID:39964338

Cost-Effectiveness Analysis of Upadacitinib in Patients With Moderately to Severely Active Ulcerative Colitis in Greece., PMID:39954537

An update on the safety of biologic therapies for the treatment of polyarticular juvenile idiopathic arthritis., PMID:39946290

Tumor Necrosis Factor-Alpha Inhibitor Use and Malignancy Risk: A Systematic Review and Patient Level Meta-Analysis., PMID:39941759

A Longitudinal Post-authorization Safety Study of Golimumab in Treatment of Ulcerative Colitis: A Cohort Study in Denmark and Sweden, 2013-2021., PMID:39913070

Incidence rates of tuberculosis and inflammatory bowel disease in patients with ankylosing spondylitis treated with biologics in Korea., PMID:39854270

Successful Treatment of Refractory Ulcerative Colitis With 5-Aminosalicylic Acid Intolerance and Biologic Therapy Resistance Using Combined Granulocyte and Monocyte Adsorptive Apheresis., PMID:39834662

Paradoxical Inflammatory Bowel Disease Induced by Golimumab in a Patient With Ankylosing Spondylitis: A Case Report and Systematic Review., PMID:39807347

Construct validity and responsiveness of ASAS Health Index assessed in two longitudinal studies of tumour necrosis factor alpha inhibitor initiation and dose reduction in patients with axial spondyloarthritis., PMID:39794273

Real-World Persistence and Effectiveness of Upadacitinib versus Other Janus Kinase Inhibitors and Tumor Necrosis Factor Inhibitors in Australian Patients with Rheumatoid Arthritis., PMID:39757285

Treatment Persistence Among Anti-Tumor Necrosis Factor-experienced Patients With Ulcerative Colitis Switching to a Biologic With a Different Mode of Action or Cycling to Another Anti-Tumor Necrosis Factor Agent., PMID:39743427

Uncovering novel therapeutic clues for hypercoagulable active ulcerative colitis: novel findings from old data., PMID:39735422

Effectiveness and Treatment Persistence of Vedolizumab Compared to Anti-Tumour Necrosis Factor-α in Patients With Crohn's Disease: A Systematic Literature Review and Meta-Analysis., PMID:39707930

Persistence of advanced therapies in patients with inflammatory bowel disease: retrospective cohort study using a large healthcare claims database in Japan., PMID:39701922

Pulmonary toxicity assessment of tumor necrosis factor α inhibitors in the treatment of IBD: a real world study based on US food and drug administration adverse events reporting system (FAERS)., PMID:39695351

Datasheet

Document Download

Research Grade Golimumab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

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Research Grade Golimumab [DHB94404]
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