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Research Grade Ranibizumab

Catalog #:   DHD12601 Specific References (99) DATASHEET
Host species: Humanized
Isotype: Fab-G1-kappa
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHD12601

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

Fab-G1-kappa

Clonality

Monoclonal

Target

Vascular endothelial growth factor A, VPF, VEGFA, VEGF, Vascular permeability factor, VEGF-A

Concentration

1.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein L purified from cell culture supernatant.

Accession

P15692

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

Fab-12 variant Y0317, RhuFab, CAS: 347396-82-1

Clone ID

Ranibizumab

Data Image
  • Bioactivity
    Detects Human VEGFA in indirect ELISAs.
  • SDS-PAGE
    SDS PAGE for Ranibizumab
References

Five-Year Outcomes of Panretinal Photocoagulation vs Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy: A Randomized Clinical Trial, PMID: 30043039

Ranibizumab for myopic choroidal neovascularization, PMID: 33003962

Aflibercept, bevacizumab or ranibizumab for diabetic macular oedema: recent clinically relevant findings from DRCR.net Protocol T, PMID: 28837425

Ranibizumab versus laser therapy for the treatment of very low birthweight infants with retinopathy of prematurity (RAINBOW): an open-label randomised controlled trial, PMID: 31522845

Ranibizumab: A Review in Retinopathy of Prematurity, PMID: 33447937

The Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration: Results from the Randomized Phase 2 Ladder Clinical Trial, PMID: 30946888

Comparative efficacy of bevacizumab, ranibizumab, and aflibercept for treatment of macular edema secondary to retinal vein occlusion: a systematic review and network meta-analysis, PMID: 30071180

Effectiveness and safety of ranibizumab 0.5 mg in treatment-naïve patients with diabetic macular edema: Results from the real-world global LUMINOUS study, PMID: 32492069

The cost-effectiveness of bevacizumab, ranibizumab and aflibercept for the treatment of age-related macular degeneration-A cost-effectiveness analysis from a societal perspective, PMID: 29772018

Visual Field Changes Over 5 Years in Patients Treated With Panretinal Photocoagulation or Ranibizumab for Proliferative Diabetic Retinopathy, PMID: 31999300

Efficacy and Treatment Burden of Intravitreal Aflibercept Versus Intravitreal Ranibizumab Treat-and-Extend Regimens at 2 Years: Network Meta-Analysis Incorporating Individual Patient Data Meta-Regression and Matching-Adjusted Indirect Comparison, PMID: 32222903

Clinical effectiveness of ranibizumab and conbercept for neovascular age-related macular degeneration: a meta-analysis, PMID: 30464394

Ranibizumab for age-related macular degeneration, PMID: 22309606

Ranibizumab and digital ischemia, PMID: 29425544

Assessing the role of ranibizumab in improving the outcome of glaucoma filtering surgery and neovascular glaucoma, PMID: 29781319

Ranibizumab and aflibercept for the treatment of wet age-related macular degeneration, PMID: 26076760

Switching between ranibizumab and aflibercept for the treatment of neovascular age-related macular degeneration, PMID: 29476754

Efficacy and Safety of a Proposed Ranibizumab Biosimilar Product vs a Reference Ranibizumab Product for Patients With Neovascular Age-Related Macular Degeneration: A Randomized Clinical Trial, PMID: 33211076

Ranibizumab Population Pharmacokinetics and Free VEGF Pharmacodynamics in Preterm Infants With Retinopathy of Prematurity in the RAINBOW Trial, PMID: 32855889

[Ranibizumab and aflibercept for diabetic macular edema-retrospective study with real-life data after 12 months], PMID: 31705192

Intravitreal ranibizumab and dexamethasone implant injections as primary treatment of diabetic macular edema: simultaneously double protocol, PMID: 32398852

Real-World Effectiveness and Real-World Cost-Effectiveness of Intravitreal Aflibercept and Intravitreal Ranibizumab in Neovascular Age-Related Macular Degeneration: Systematic Review and Meta-Analysis of Real-World Studies, PMID: 31728825

Intraocular Pharmacokinetics of 10-fold Intravitreal Ranibizumab Injection Dose in Rabbits, PMID: 32818095

Ranibizumab plus fufang xueshuantong capsule versus ranibizumab alone for exudative age-related macular degeneration, PMID: 32962487

Ranibizumab for the treatment of wet AMD: a summary of real-world studies, PMID: 26634711

Intravitreal Ranibizumab Injection for the Treatment of Retinopathy of Prematurity, PMID: 30995663

Ranibizumab treatment patterns in prior ranibizumab-treated neovascular age-related macular degeneration patients: Real-world outcomes from the LUMINOUS study, PMID: 33378369

Therapeutic Monoclonal Antibodies and Fragments: Ranibizumab, PMID: 26501149

Photodynamic therapy in combination with ranibizumab versus ranibizumab monotherapy for wet age-related macular degeneration: A systematic review and meta-analysis, PMID: 29753123

Renal Biomarkers for Treatment Effect of Ranibizumab for Diabetic Macular Edema, PMID: 32908935

Ranibizumab in the Treatment of Diabetic Macular Edema: A Review of the Current Status, Unmet Needs, and Emerging Challenges, PMID: 28484955

Real-world effectiveness and safety of ranibizumab for the treatment of myopic choroidal neovascularization: Results from the LUMINOUS study, PMID: 31961888

Intravitreal Ranibizumab for the Treatment of Visual Impairment Due to Choroidal Neovascularization Associated with Rare Diseases: Cost-Effectiveness in the UK, PMID: 30726549

Intravitreal ranibizumab reduced ocular blood flow and aqueous cytokine levels and improved retinal morphology in patients with diabetic macular edema, PMID: 33303870

Post-Ranibizumab injection endophthalmitis in aggressive posterior retinopathy of prematurity, PMID: 31124535

Ranibizumab for Macular Edema Secondary to Central and Branch Retinal Vein Occlusion in Patients Younger Than 50 Years of Age, PMID: 32685489

Aflibercept for neovascular age-related macular degeneration, PMID: 26857947

Ranibizumab port delivery system (RPDS): realising long awaited dream of prolonged VEGF suppression, PMID: 31165769

Switching from ranibizumab and aflibercept to bevacizumab therapy in neovascular age-related macular degeneration patients, PMID: 32375502

Cost-Minimization Analysis of Ranibizumab Versus Aflibercept for Treating Saudi Patients With Visual Impairment Owing to Age-Related Macular Degeneration or Diabetic Macular Edema, PMID: 32247191

Biomechanical properties of the cornea following intravitreal ranibizumab injection, PMID: 33165643

Therapeutic effects of ranibizumab in patients with polypoidal choroidal vasculopathy, PMID: 31324161

Cardiovascular risk in patients receiving ranibizumab for exudative age-related macular degeneration: a nationwide self-controlled case-series study, PMID: 32522792

Outcomes and costs of Ranibizumab and Aflibercept treatment in a health-service research context, PMID: 29486762

Evaluation of ranibizumab and aflibercept for the treatment of diabetic macular edema in daily clinical practice, PMID: 31644594

Ranibizumab in macular oedema secondary to branch retinal vein occlusion - 24 months of treatment, PMID: 32397721

Use of Bevacizumab and Ranibizumab for Wet Age-Related Macular Degeneration: Influence of CATT Results and Introduction of Aflibercept, PMID: 31100217

Ranibizumab for the treatment of choroidal neovascularization due to cause other than age related macular degeneration, PMID: 31779462

Real-world outcomes with ranibizumab in branch retinal vein occlusion: The prospective, global, LUMINOUS study, PMID: 32555630

Effect of intravitreal ranibizumab pretreatment on vitrectomy in young patients with proliferative diabetic retinopathy, PMID: 32005066

Comment on: 'Comparing safety and efficacy of Bevacizumab, Ranibizumab and Ranibizumab biosimilar in Retinopathy of prematurity'., PMID:40527930

Unusual presentation of retinitis pigmentosa with vasoproliferative tumour., PMID:40527540

Clinical Trials of Aflibercept Biosimilars: A Review., PMID:40526023

Interventions for central serous chorioretinopathy: a network meta-analysis., PMID:40522203

Real-World 5-Year Outcomes of Age-Related Macular Degeneration with Bevacizumab as First-Line Anti-VEGF., PMID:40517351

Six-year findings of polypoidal choroidal vasculopathy in the EVEREST II study: Japanese subgroup analysis., PMID:40504425

Efficacy of switching from existing anti-vascular endothelial growth factor drugs to ranibizumab biosimilar in neovascular age-related macular degeneration., PMID:40500585

Usage of brolucizumab as treatment for wet age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV): A narrative review., PMID:40489855

Effect of ranibizumab on diabetic retinopathy via the vascular endothelial growth factor/STAT3/glial fibrillary acidic protein pathway., PMID:40487605

Response to 'Comment on: 'Comparing safety and efficacy of Bevacizumab, Ranibizumab and Ranibizumab biosimilar in Retinopathy of prematurity"., PMID:40483306

Anti-VEGFs for Diabetic Macular Oedema: Analysis of Efficacy, Safety, and Cost of More Durable Therapies from a Dutch Societal Perspective., PMID:40481910

Intravitreal anti-vascular endothelial growth factor injections and risks of stroke in patients with neovascular age-related macular degeneration-A registry-based cohort study., PMID:40481786

Modeling the Ocular Pharmacokinetics and Pharmacodynamics of Ranibizumab for Improved Understanding and Data Collection Strategies in Ocular Diseases., PMID:40478563

EFFICACY AND PROGNOSIS OF ANTI-VEGF AGENTS COMBINED WITH PANRETINAL PHOTOCOAGULATION IN DIABETIC RETINOPATHY: A CLINICAL OBSERVATIONAL STUDY., PMID:40466685

Infographic: intravitreal therapy for uveitic macular edema-ranibizumab versus methotrexate versus the dexamethasone implant: the MERIT trial results., PMID:40457097

Association between intravitreal anti-vascular endothelial growth factor agents and hypertension: a meta-analysis., PMID:40456283

Anti-VEGF Agents Clearance Through the Aqueous Outflow Pathway in a Rat Model., PMID:40455045

Several Common Genetic Variations Associate With Functional or Anatomic Effects of Anti-VEGF Treatment in Conditions With Macular Edema., PMID:40455044

Targeting VEGF With 99mTc-Labeled Ranibizumab for Noninvasive Diagnosis of Non-Small Cell Lung Cancer., PMID:40444333

Managing Choroidal Neovascularization in Pseudoxanthoma Elasticum: Outcomes of Vitrectomy and Intravitreal Ranibizumab/Aflibercept Therapy-A Case Report., PMID:40438152

Oral lamivudine in diabetic macular edema: A randomized, double-blind, placebo-controlled clinical trial., PMID:40436012

Area Under the Curve Analysis in a Real-World Cohort of Finnish Patients Treated for Neovascular Age-Related Macular Degeneration., PMID:40423616

Real-Life Treatment Intervals and Morphological Outcomes Following the Switch to Faricimab Therapy in Neovascular Age-Related Macular Degeneration., PMID:40423060

Effectiveness and safety of anti-vascular endothelial growth factor therapies for macular edema in retinal vein occlusion: A systematic review and network meta-analysis of randomized controlled trials., PMID:40419166

Subretinal tissue plasminogen activator in polypoidal choroidal vasculopathy-related submacular haemorrhage and exudative retinal detachment., PMID:40409770

Efficacy and safety of prophylactic simultaneous intravitreal moxifloxacin injection with standard intravitreal anti-VEGF injection procedure in cases of cystoid macular edema and macular neovascularization., PMID:40405143

Comparison of three loading doses of bevacizumab and ranibizumab for macular edema due to branch retinal vein occlusion., PMID:40405136

[Age-related macular degeneration - Part 2: therapeutic options for AMD]., PMID:40389215

A Study of Visual Outcomes and Spectral Domain Optical Coherence Tomography (SD-OCT) Biomarker Changes in Patients Treated With Ranibizumab for Diabetic Macular Edema in a Tertiary Hospital., PMID:40385737

Effect of simultaneous intravitreal ranibizumab and extended-release dexamethasone injection on patients with naïve versus refractory retinal vein occlusion macular edema: a prospective, multicenter, and interventional open-label study., PMID:40385115

Socioeconomic Disparities in Intravitreal Injection Use and Anti-VEGF Agent Selection: Aflibercept/Ranibizumab Versus Bevacizumab., PMID:40383690

Combining ranibizumab with calcium dobesilate to reduce injection frequency in diabetic macular edema treatment., PMID:40381058

Therapeutic outcomes of ranibizumab for zone ii stage 2 retinopathy of prematurity with plus disease., PMID:40377801

Recurrence of Macular Edema in Branch Retinal Vein Occlusion-A Comparison of Aflibercept and Ranibizumab in a Randomized Trial., PMID:40373873

Sustainable Practices in Anti-VEGF Therapy: A 15-Year Bibliometric Analysis of Ranibizumab for Age-Related Macular Degeneration., PMID:40365539

Planned vs. Performed Treatment Regimens in Diabetic Macular Edema: Real-World Evidence from the PACIFIC Study., PMID:40364151

Dynamic Changes of Aqueous Matrix Metalloproteinases and Imaging Correlation in Retinal Vein Occlusion Following Ranibizumab Therapy., PMID:40359464

Silicone oil microdroplets from syringes with intravitreal anti-vascular endothelial growth factor and complement inhibitor injections., PMID:40359347

OCTA as a reliable prognostic tool for active NVD treated with Panretinal Photocoagulation and/or ranibizumab., PMID:40359330

[Biosimilars of ranibizumab in retinal diseases: new possibilities in ophthalmology]., PMID:40353548

Long-term outcomes of the observe-and-plan regimen in treating neovascular age-related macular degeneration: a retrospective real-life analysis., PMID:40348918

Anti-VEGF drugs compared with laser photocoagulation for the treatment of diabetic retinopathy: a systematic review and economic analysis., PMID:40347224

PDVR stage A management: Insights from combined PRP and anti-VEGF treatment outcomes., PMID:40340516

Improved functional and morphological outcomes with faricimab in nAMD eyes with poor response to prior intravitreal anti-VEGF therapy., PMID:40338383

Contributing factors to short-term intraocular pressure elevation following intravitreal anti-VEGF injections., PMID:40335957

Endophthalmitis following intravitreal injections at a tertiary center: real-life data on incidence, risk factors, management strategies, and visual outcomes., PMID:40335933

Visual fields after anti-vascular endothelial growth factor therapy for retinopathy of prematurity., PMID:40333931

Efficacy of ranibizumab with laser in the treatment of diabetic retinopathy compare with laser monotherapy: A systematic review and meta-analysis., PMID:40331557

Uncommon Therapeutic Approaches for Patients with Recurrent Central Serous Chorioretinopathy: case report and literature review., PMID:40330964

Datasheet

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Research Grade Ranibizumab.pdf

 

$ 426
Product specifications
100 μg 426 1 mg 1704

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Research Grade Ranibizumab [DHD12601]
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