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Research Grade Omalizumab

Catalog #:   DHJ92701 Specific References (100) DATASHEET
Host species: Humanized
Isotype: IgG1-kappa
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHJ92701

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

Ig epsilon chain C region, IGHE, Ig epsilon chain C region ND, Immunoglobulin heavy constant epsilon

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01854

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

IGE25, olizumab, pSVIE26, rhuMab-E25, CAS: 242138-07-4,MaE11

Clone ID

Omalizumab

Data Image
  • SDS-PAGE
    SDS PAGE for Omalizumab
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials, PMID: 32524991

Roles of omalizumab in various allergic diseases, PMID: 32067933

The use of omalizumab in allergen immunotherapy, PMID: 29315922

Omalizumab Updosing in Chronic Spontaneous Urticaria: an Overview of Real-World Evidence, PMID: 32418171

Omalizumab in the Treatment of Chronic Inducible Urticaria, PMID: 27717421

From IgE to Omalizumab, PMID: 27864548

Omalizumab, the first available antibody for biological treatment of severe asthma: more than a decade of real-life effectiveness, PMID: 30400762

Off-Label Uses of Omalizumab, PMID: 26048266

Omalizumab for atopic dermatitis: evidence for and against its use, PMID: 30717578

Omalizumab for Severe Asthma: Beyond Allergic Asthma, PMID: 30310816

Omalizumab for chronic urticaria in children younger than 12 years, PMID: 31082483

Benefits and Harms of Omalizumab Treatment in Adolescent and Adult Patients With Chronic Idiopathic (Spontaneous) Urticaria: A Meta-analysis of "Real-world" Evidence, PMID: 30427977

Omalizumab for the Treatment of Chronic Idiopathic Urticaria: Systematic Review of the Literature, PMID: 28226418

Efficacy and safety of omalizumab in children and adolescents with moderate-to-severe asthma: A systematic literature review, PMID: 28631599

Efficacy and effectiveness of omalizumab in the treatment of childhood asthma, PMID: 30141696

The clinical benefit of mepolizumab replacing omalizumab in uncontrolled severe eosinophilic asthma, PMID: 31049972

Omalizumab in children with uncontrolled allergic asthma: Review of clinical trial and real-world experience, PMID: 28477722

Effect of omalizumab on lung function and eosinophil levels in adolescents with moderate-to-severe allergic asthma, PMID: 31760132

Omalizumab treatment in patients with chronic inducible urticaria: A systematic review of published evidence, PMID: 28751232

Rituximab and Omalizumab for the Treatment of Bullous Pemphigoid: A Systematic Review of the Literature, PMID: 30421306

The anti-IgE mAb omalizumab induces adverse reactions by engaging Fcγ receptors, PMID: 31770111

Omalizumab in children and adolescents with chronic spontaneous urticaria: Case series and review of the literature, PMID: 32358910

How to Treat Patients with Chronic Spontaneous Urticaria with Omalizumab: Questions and Answers, PMID: 31374358

Mabs for treating asthma: omalizumab, mepolizumab, reslizumab, benralizumab, dupilumab, PMID: 32401603

Pediatric use of omalizumab for allergic asthma, PMID: 32241196

Omalizumab in severe eczema, PMID: 32725741

Omalizumab for Atopic Dermatitis: Overtreatment or Lifesaver?, PMID: 31764954

Real-world safety and efficacy of omalizumab in patients with severe allergic asthma: A long-term post-marketing study in Japan, PMID: 30053973

[Omalizumab: Beyond anti-IgE properties], PMID: 28189435

Omalizumab retreatment in patients with chronic spontaneous urticaria: a systematic review of published evidence, PMID: 32108461

Should omalizumab be used in severe asthma/COPD overlap?, PMID: 30043557

The XTEND-CIU study: Long-term use of omalizumab in chronic idiopathic urticaria, PMID: 29132956

Novel targets of omalizumab in asthma, PMID: 27798419

Role of Biologics in Asthma, PMID: 30525902

Omalizumab re-treatment rates in chronic spontaneous urticaria, PMID: 32378397

Omalizumab: living up to PROMises, PMID: 30604545

The discovery and development of omalizumab for the treatment of asthma, PMID: 25979110

Short- and long-term real-world effectiveness of omalizumab in severe allergic asthma: systematic review of 42 studies published 2008-2018, PMID: 30763137

New insights into the utility of omalizumab, PMID: 30690050

A review of omalizumab for the management of severe asthma, PMID: 27528798

Omalizumab Is an Effective Intervention in Severe Asthma with Fungal Sensitization, PMID: 32561499

Omalizumab and mepolizumab in the landscape of biological therapy for severe asthma in children: how to choose?, PMID: 31779657

Omalizumab and Mast Cell Disorders: Are We There Yet?, PMID: 31495435

The Use of Omalizumab in Food Oral Immunotherapy, PMID: 27628022

Algorithm for Treatment of Chronic Spontaneous Urticaria with Omalizumab, PMID: 30107875

Response of omalizumab in normocomplementemic urticarial vasculitis, PMID: 32145404

Omalizumab treatment in adolescents with chronic spontaneous urticaria: Efficacy and safety, PMID: 32467066

Omalizumab concentrations in pregnancy and lactation: A case study, PMID: 32544544

Update on Omalizumab for Urticaria: What's New in the Literature from Mechanisms to Clinic, PMID: 29744661

Omalizumab or dupilumab for chronic rhinosinusitis with nasal polyposis, PMID: 33160644

Cold urticaria patients can be susceptible to anaphylaxis during diagnostic cold provocation tests., PMID:40527541

Describing Clinical Characteristics and Treatment Course of Patients with Hereditary Alpha-tryptasemia: A Single-center Study., PMID:40515774

Biologics in IgE-mediated food allergy: A systematic review and meta-analysis of interventional studies., PMID:40510735

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity Profiles of a Single-Dose JYB1904 in Healthy Chinese Participants: A Phase Ia, Randomized, Double-Blind, Placebo-Controlled Study., PMID:40504164

Health care resource utilization of patients with asthma and food allergy initiating omalizumab., PMID:40497014

Corrigendum to "Omalizumab may protect allergic patients against COVID-19: A systematic review" [World Allergy Organ J 16 (2) (2023) 1-19]., PMID:40496753

Comparative Analysis of ICS Combined with LABA versus Addition of Omalizumab on Transcriptomic Expression Profiles in Patients with Allergic Asthma., PMID:40491983

Aspirin-Exacerbated Respiratory Disease in the era of biologics., PMID:40490219

Advancements in Biologic Therapies for Pediatric Asthma: Emerging Therapies and Future Directions., PMID:40486460

Identification of the Top 15 Drugs Associated With Anaphylaxis: A Pharmacovigilance Study., PMID:40484712

A nationwide experience of biological treatments in children with eosinophilic esophagitis., PMID:40483369

How to manage hypersensitivity reactions to enzyme replacement therapy in lysosomal storage diseases?, PMID:40481554

Prognostic calculator of the clinical response to antihistamines in chronic urticaria: External validation., PMID:40480548

Azathioprine for the Treatment of Chronic Spontaneous Urticaria Refractory to Antihistamines, Omalizumab, and Ciclosporin: A Case Series., PMID:40480489

Equivalence of SYN008 versus omalizumab in patients with refractory chronic spontaneous urticaria: A multicenter, randomized, double-blind, parallel-group, active-controlled phase III study., PMID:40474341

The Efficacy of Different Dosing Regimens of Omalizumab in children and adolescents with chronic spontaneous urticaria based on real-life data., PMID:40466628

In brief: Omlyclo - an omalizumab biosimilar interchangeable with Xolair., PMID:40459407

Evaluating remibrutinib in the treatment of chronic spontaneous urticaria., PMID:40455080

Efficacy and safety of CT-P39, an omalizumab biosimilar, in chronic spontaneous urticaria: 16-week follow-up study., PMID:40454995

Hereditary alpha-tryptasemia - a potential cause of severe anaphylactic reactions and a modifier of mast cell diseases., PMID:40450750

Introduction of Allergenic Foods After Treatment with Omalizumab., PMID:40447195

Efficacy and safety of Omalizumab in the treatment of CSU: a meta-analysis of a randomized controlled trial., PMID:40439896

Omalizumab Efficacy in Chronic Rhinosinusitis Patients with Recurrent Nasal Polyps: An open-label, single-center, randomized, controlled study., PMID:40437843

Omalizumab in Food Allergy in Children: Current Evidence and Future Perspectives., PMID:40430110

Four-week IgE/baseline IgE ratio combined with tryptase predicts clinical outcome in omalizumab-treated children with moderate-to-severe asthma., PMID:40417314

Anti-KIT Barzolvolimab for Chronic Spontaneous Urticaria., PMID:40415544

Treatment of eosinophilic dermatosis of hematologic malignancy with omalizumab., PMID:40413842

Redefining Omalizumab Discontinuation in Chronic Spontaneous Urticaria: The Value of Optimization and Predictive Factors of Relapse. A 52-Week Multicenter Study., PMID:40403841

Bioinformatics analysis of FCER1A as a key immune marker in dilated cardiomyopathy and systemic lupus erythematosus., PMID:40401008

Both Extrinsic and Intrinsic Atopy in Chronic Spontaneous Urticaria Patients Indicate a Favorable Response to Omalizumab Treatment., PMID:40397623

Resolution of Patient's Anaphylaxis to the Moderna COVID-19 Vaccine by Desensitization., PMID:40386747

Anaphylaxis in children: Latest insights., PMID:40380371

Value-based care in allergy-immunology: Beyond the quality-adjusted life year., PMID:40380361

Emerging Therapies in the Treatment of Prurigo Nodularis: Biological Therapy and Systematic Review of Literature., PMID:40372666

Biologic Therapies for Severe Asthma: Current Insights and Future Directions., PMID:40364184

Omalizumab dosing patterns and drug survival in adult patients with chronic spontaneous urticaria., PMID:40357715

Combination of Allergen-Specific Immunotherapy With Biologics in Severe Asthma: Counterintuitive or Rational?, PMID:40349962

Requalification of patients with severe asthma for biological therapy-Practical 'ReQuaBi' rate decision scheme based on the analytical model., PMID:40348613

Reappraisal of Biologic Efficacy from Phase 3 Trials in Refractory Chronic Rhinosinusitis and Nasal Polyps., PMID:40340024

Omalizumab: a broader role in dermatology? Evidence and the road ahead., PMID:40338196

Pityriasis rosea-like eruption induced by omalizumab: a case report of a rare side effect., PMID:40330944

Scientific developments in understanding food allergy prevention, diagnosis, and treatment., PMID:40330465

Biological and target synthetic treatments for chronic spontaneous urticaria: A systematic review and network meta-analysis., PMID:40326848

Spectrum and Impact of Reported Side Effects of Omalizumab in Patients With Chronic Urticaria: A Long-Term Multicentre Real-World Study., PMID:40325793

Glycobiology of IgE., PMID:40322856

Recurrent Chronic Idiopathic Urticaria Post-hysterectomy and Loss of Xolair Effectiveness: A Case Report., PMID:40322383

Structural and Functional Insights Into IgE Receptor Interactions and Disruptive Inhibition., PMID:40305523

Efficacy of tiotropium bromide on spirometric measurements and control of asthma in real life: data from a 1-year clinical follow-up., PMID:40304436

Mental Health Interventions in Refractory Chronic Spontaneous Urticaria: A Call to Expand Treatment Guidelines., PMID:40303526

Secukinumab as a Novel Treatment for Chronic Netherton Syndrome in a Young Adult., PMID:40299794

Datasheet

Document Download

Research Grade Omalizumab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

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Research Grade Omalizumab [DHJ92701]
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