Catalog No.
RHE16601
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Chimeric
Isotype
IgG1
Clonality
Monoclonal
Target
FLK-1, Kinase insert domain receptor, VEGFR2, Fetal liver kinase 1, CD309, Vascular endothelial growth factor receptor 2, Protein-tyrosine kinase receptor flk-1, FLK1, VEGFR-2, KDR
Concentration
1.2 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P35968
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
IMC-1C11
Targeting angiogenesis in bladder cancer., PMID:19336017
[Anti-angiogenesis targeting drugs: a review]., PMID:18423135
Metronomic chemotherapy dosing-schedules with estramustine and temozolomide act synergistically with anti-VEGFR-2 antibody to cause inhibition of human umbilical venous endothelial cell growth., PMID:17851838
Targeting autocrine and paracrine VEGF receptor pathways inhibits human lymphoma xenografts in vivo., PMID:15238424
Gateways to clinical trials., PMID:14571286
Gateways to clinical trials., PMID:12949633
A phase I study of anti-kinase insert domain-containing receptor antibody, IMC-1C11, in patients with liver metastases from colorectal carcinoma., PMID:12684400
Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity., PMID:12646950
Technology evaluation: IMC-1C11, ImClone Systems., PMID:11525567
Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration., PMID:10953026
For research use only. Not for human or drug use.
