Research Grade Bentracimab

Catalog No.

DGK10801

Expression system

Mammalian Cells

Species reactivity

General

Host species

Human

Isotype

Fab-G1-lambda

Clonality

Monoclonal

Target

Ticagrelor

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

CAS: 274693-27-5

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

MEDI2452, anti-ticagrelor, antidote for ticagrelor, CAS: 274693-27-5

Clone ID

Bentracimab

ANMCO/SIMEU consensus document on the use of reversal agents for antithrombotic therapies in patients with ongoing bleeding or at high risk of haemorrhagic events., PMID:38784674

Clinical and Pre-Clinical Pharmacokinetics and Pharmacodynamics of Bentracimab., PMID:37118383

Reversal of Platelet Inhibition in Patients Receiving Ticagrelor., PMID:39077695

Bentracimab for Ticagrelor Reversal in Patients Undergoing Urgent Surgery., PMID:38319214

Population pharmacokinetic-pharmacodynamic modeling of PB2452, a monoclonal antibody fragment being developed as a ticagrelor reversal agent, in healthy volunteers., PMID:34713987

Ticagrelor use and practice patterns among Canadian cardiac surgeons., PMID:34028081

Document Download

Research Grade Bentracimab.pdf