Catalog No.
YHJ56801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Gly120
Predicted molecular weight
16.44 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H492
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, MAP1 light chain 3-like protein 1, Microtubule-associated protein 1 light chain 3 alpha, MAP1A/MAP1B LC3 A, MAP1LC3A, Microtubule-associated proteins 1A/1B light chain 3A, MAP1A/MAP1B light chain 3 A
Note
For research use only.
Gene signatures of endoplasmic reticulum stress and mitophagy for prognostic risk prediction in lung adenocarcinoma., PMID:38813617
PGAM5 interacts with and maintains BNIP3 to license cancer-associated muscle wasting., PMID:38919131
Serum L C3-II levels in type 2 diabetic patients with impaired renal functions., PMID:38943738
Britannin suppresses MCF-7 breast cancer cell growth by inducing apoptosis and inhibiting autophagy., PMID:38948174
The Role of LC3-Associated Phagocytosis Inhibits the Inflammatory Response in Aspergillus fumigatus Keratitis., PMID:38953845
Individual Atg8 paralogs exhibit unique properties in streptococcus pneumoniae-induced hierarchical autophagy., PMID:38963025
Dysregulated Apoptosis and Autophagy in Childhood Epilepsy: Correlation to Clinical and Pharmacological Patterns., PMID:38964348
Structure-Based Design and Discovery of a Potent and Cell-Active LC3A/B Covalent Inhibitor., PMID:39010658
Identification of MAP1LC3A as a promising mitophagy-related gene in polycystic ovary syndrome., PMID:39043888
Assessment of Non-canonical Functions of the Autophagy Proteins in LC3-Associated Phagocytosis and LC3-Associated Endocytosis., PMID:39046619
TMEM9 activates Rab9-dependent alternative autophagy through interaction with Beclin1., PMID:39078420
ZDHHC7-mediated S-palmitoylation of ATG16L1 facilitates LC3 lipidation and autophagosome formation., PMID:39087410
High-Throughput Screening for LC3/GABARAP Binders Utilizing the Fluorescence Polarization Assay., PMID:39115669
Thermodynamic Characterization of LC3/GABARAP:Ligand Interactions by Isothermal Titration Calorimetry., PMID:39115670
Sigma-1 receptor recruits LC3 mRNA to ER-associated omegasomes to promote localized LC3 translation enabling functional autophagy., PMID:39128005
Evidence of Mitophagy in Lens Capsule Epithelial Cells of Patients With Pseudoexfoliation Syndrome., PMID:39140812
Spatial Activation of Autophagy in Human Placenta-Related Tissue During Labor: A Possible Mechanism for Labor Onset., PMID:39177075
Thiouracil and triazole conjugate induces autophagy through the downregulation of Wnt/β-catenin signaling pathway in human breast cancer cells., PMID:39257214
Non-autophagic Golgi-LC3 lipidation facilitates TFE3 stress response against Golgi dysfunction., PMID:39284911
Heme deficiency in skeletal muscle exacerbates sarcopenia and impairs autophagy by reducing AMPK signaling., PMID:39333763
Migratory autolysosome disposal mitigates lysosome damage., PMID:39347717
Transcriptome profiling of DPP stimulated DPSCs identifies the role of autophagy in odontogenic differentiation., PMID:39389242
Small Molecules Inducing Autophagic Degradation of Expanded Polyglutamine Protein through Interaction with Both Mutant ATXN3 and LC3., PMID:39409036
Functional Relationships between L1CAM, LC3, ATG12, and Aβ., PMID:39409157
Promising and challenging phytochemicals targeting LC3 mediated autophagy signaling in cancer therapy., PMID:39436197
LC3-associated phagocytosis and human diseases: Insights from mechanisms to therapeutic potential., PMID:39446073
The cGAS-STING mediated crosstalk between innate immunity and autophagy in leishmaniasis using mathematical modeling: Uncovering new therapeutic avenues., PMID:39486567
Evaluation of LC3-II Release via Extracellular Vesicles in Relation to the Accumulation of Intracellular LC3-positive Vesicles., PMID:39494889
Critical assessment of LC3/GABARAP ligands used for degrader development and ligandability of LC3/GABARAP binding pockets., PMID:39587067
Selective autophagy impedes KSHV entry after recruiting the membrane damage sensor galectin-8 to virus-containing endosomes., PMID:39602307
[Ferroptosis-related genes in osteoporosis: a bioinformatics analysis and in vitro study]., PMID:39608795
Investigation of Oxidative-Stress Impact on Human Osteoblasts During Orthodontic Tooth Movement Using an In Vitro Tension Model., PMID:39769290
ATG9 promotes autophagosome formation through interaction with LC3., PMID:39787789
High glucose induces renal tubular epithelial cell senescence by inhibiting autophagic flux., PMID:39789393
[Impacts of curcumin on proliferation, migration and cisplatin resistance of bladder cancer cells by regulating LKB1-AMPK-LC3 signaling pathway]., PMID:39799420
A Multi-Omics Analysis of a Mitophagy-Related Signature in Pan-Cancer., PMID:39859167
Mendelian randomization analysis of plasma proteins reveals potential novel tumor markers for gastric cancer., PMID:39875498
Bioinformatics analysis combined with experimental validation reveals the biological role of the ILK gene in prostate cancer., PMID:39890647
The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outside-in signaling., PMID:39905041
uN2CpolyG-mediated p65 nuclear sequestration suppresses the NF-κB-NLRP3 pathway in neuronal intranuclear inclusion disease., PMID:39920690
The LC3-interacting region of NBR1 is a protein interaction hub enabling optimal flux., PMID:39928048
Enhanced In Vitro and In Vivo Autophagy Suppression via LC3 siRNA-Loaded "Smart" Nanoparticles and Doxorubicin Combination Therapy in Triple Negative Breast Cancer., PMID:40056448
Skeletal muscle preservation in arctic ground squirrels during hibernation season., PMID:40122513
Mycobacterium tuberculosis phagosome Ca2+ leakage triggers multimembrane ATG8/LC3 lipidation to restrict damage in human macrophages., PMID:40138395
Transcriptome remodeling and adaptive preservation of muscle protein content in hibernating black bears., PMID:40166218
A non-fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers., PMID:40181489
Influenza A Virus Induces Autophagosome by Inhibiting LTCC/Calpain 2/LC3A Signaling to Promote Viral Replication., PMID:40358023
A pH-Sensitive NIR Fluorescent Probe as a Protagonist in the Discovery of New LC3 Ligands Facilitating the Construction of ATTECs., PMID:40375755
Potential therapeutic targets for deep vein thrombosis: A proteome-wide Mendelian randomization study., PMID:40462713
Influenza A virus subverts the LC3-pericentrin dynein adaptor complex for host cytoplasm entry., PMID:40498831
For research use only. Not for human or drug use.
