Catalog No.
YHJ54201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met52-Leu336
Predicted molecular weight
34.87 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H0P0
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cytosolic 5'-nucleotidase III, P5N-1, 7-methylguanosine phosphate-specific 5'-nucleotidase, NT5C3, 7-methylguanosine nucleotidase, P5N1, p36, NT5C3A, cN-III, Cytosolic 5'-nucleotidase 3A, UMPH1, P5'N-1, Cytosolic 5'-nucleotidase 3, Uridine 5'-monophosphate hydrolase 1, Pyrimidine 5'-nucleotidase 1, PN-I
Note
For research use only.
Human erythrocyte pyrimidine 5-nucleotidase, PN-I, is identical to p36, a protein associated to lupus inclusion formation in response to alpha-interferon., PMID:10942414
Up-regulation of liver glucose-6-phosphatase in x-linked hypophosphatemic mice., PMID:12173068
Expression of a releasable form of annexin II by human keratinocytes., PMID:12210740
The prognostic value of cN-II and cN-III enzymes in adult acute myeloid leukemia., PMID:16330448
Gene symbol: NT5C3. Disease: haemolytic anemia., PMID:16402212
Gene symbol: NT5C3. Disease: pyrimidine 5'-nucleotidase (P5'N) deficiency., PMID:17128459
Overexpression of hUMP1/POMP proteasome accessory protein enhances proteasome-mediated antioxidant defence., PMID:17349762
Synergistic inhibition of pancreatic adenocarcinoma cell growth by trichostatin A and gemcitabine., PMID:17555830
Differential allelic expression in leukoblast from patients with acute myeloid leukemia suggests genetic regulation of CDA, DCK, NT5C2, NT5C3, and TP53., PMID:18775979
Cytosolic 5'-nucleotidase III (NT5C3): gene sequence variation and functional genomics., PMID:19623099
Exploratory bioinformatics study of lncRNAs in Alzheimer's disease mRNA sequences with application to drug development., PMID:23662159
Bayseian genomic models for the incorporation of pathway topology knowledge into association studies., PMID:23934611
NT5C3 polymorphisms and outcome of first induction chemotherapy in acute myeloid leukemia., PMID:25000516
Pyrimidine-5'-nucleotidase Campinas, a new mutation (p.R56G) in the NT5C3 gene associated with pyrimidine-5'-nucleotidase type I deficiency and influence of Gilbert's Syndrome on clinical expression., PMID:25153905
Novel genes for airway wall thickness identified with combined genome-wide association and expression analyses., PMID:25517131
Identification of Target Genes Regulated by KSHV miRNAs in KSHV-Infected Lymphoma Cells., PMID:25648438
Transplantation of NSC-derived cholinergic neuron-like cells improves cognitive function in APP/PS1 transgenic mice., PMID:25681520
Assessment of mTOR-Dependent Translational Regulation of Interferon Stimulated Genes., PMID:26207988
RNA interference screening of interferon-stimulated genes with antiviral activities against classical swine fever virus using a reporter virus., PMID:26868874
Chemical Screening Identifies EUrd as a Novel Inhibitor Against Temozolomide-Resistant Glioblastoma-Initiating Cells., PMID:27090194
Proteomics reveals reduced expression of transketolase in pyrimidine 5'-nucleotidase deficient patients., PMID:27381654
JNJ872 inhibits influenza A virus replication without altering cellular antiviral responses., PMID:27451344
The intracellular pyrimidine 5'-nucleotidase NT5C3A is a negative epigenetic factor in interferon and cytokine signaling., PMID:29463777
Comprehensive Proteomics Identification of IFN-λ3-regulated Antiviral Proteins in HBV-transfected Cells., PMID:30097535
A New Homozygous Mutation (c.393-394del TA/c.393-394del TA) in the NT5C3 Gene Associated With Pyrimidine-5'-Nucleotidase Deficiency: A Case Report., PMID:30951028
NUP-98 Rearrangements Led to the Identification of Candidate Biomarkers for Primary Induction Failure in Pediatric Acute Myeloid Leukemia., PMID:33925480
The plasma peptides of Alzheimer's disease., PMID:34182925
Tracking HIV-1-Infected Cell Clones Using Integration Site-Specific qPCR., PMID:34202310
[Two novel mutations (c.830A>G, c.252+1G>A) in NT5C3A associated with hereditary pyrimidine 5'-nucleotidase deficiency: two cases report and literature review]., PMID:34547876
DIA-based quantitative proteomic analysis on the meat quality of porcine Longissimus thoracis et lumborum cooked by different procedures., PMID:34619635
Putative Concussion Biomarkers Identified in Adolescent Male Athletes Using Targeted Plasma Proteomics., PMID:34987469
Differences in clinical characteristics and lesion proteomics between inflammatory linear verrucous epidermal nevus and local verrucous epidermal nevus., PMID:35283356
A rare mutation (p.F149del) of the NT5C3A gene is associated with pyrimidine 5'-nucleotidase deficiency., PMID:36434495
Proximity extension assay-based discovery of biomarkers for disease activity in chronic inflammatory demyelinating polyneuropathy., PMID:37879899
Identification and Validation of Nicotinamide Metabolism-Related Gene Signatures as a Novel Prognostic Model for Hepatocellular Carcinoma., PMID:38827823
For research use only. Not for human or drug use.
