Catalog No.
YHG27001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln29-His343
Predicted molecular weight
38.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q10981
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Fucosyltransferase 2, SE2, Se, Galactoside alpha-(1,2)-fucosyltransferase 2, Secretor blood group alpha-2-fucosyltransferase, Alpha(1,2)FT 2, Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT2, FUT2, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2, Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT2, Secretor factor, SEC2
Fermented Dairy Products as Precision Modulators of Gut Microbiota and Host Health: Mechanistic Insights, Clinical Evidence, and Future Directions., PMID:40509473
Genetic analysis and protein modeling evaluation of a novel FUT1 variant c.683T>C (p.Met228Thr) in a Chinese individual with para-Bombay phenotype., PMID:40497798
Human and bacterial genetic variation shape oral microbiomes and health., PMID:40236410
Exploring deleterious non-synonymous SNPs in FUT2 gene, and implications for norovirus susceptibility and gut microbiota composition., PMID:40140394
FUT2-dependent fucosylation of LAMP1 promotes the apoptosis of colorectal cancer cells by regulating the autophagy-lysosomal pathway., PMID:40112906
Bacterial and host fucosylation maintain IgA homeostasis to limit intestinal inflammation in mice., PMID:39690194
Personalized nutrition and precision medicine in perimenopausal women: A minireview of genetic polymorphisms COMT, FUT2, and MTHFR., PMID:39642577
Drug repurposing against fucosyltransferase-2 via docking, STD-NMR, and molecular dynamic simulation studies., PMID:39485776
Identification of two novel variants, c.-35A>T and c.[-35A>T, 725T>G], in the FUT1 gene in a patient exhibiting the para-Bombay phenotype., PMID:39473114
Requirement for Fucosyltransferase 2 in Allergic Airway Hyperreactivity and Mucus Obstruction., PMID:39447136
FUT2 promotes colorectal cancer metastasis by reprogramming fatty acid metabolism via YAP/TAZ signaling and SREBP-1., PMID:39390072
Genome-Wide Association Study Identifies Genetic Polymorphisms for Folate-Related Biomarkers in Chinese Preconception Women., PMID:39374789
Associations Between Histo-blood Group Antigen Status in Mother-Infant Dyads and Infant Oral Rotavirus Vaccine Immunogenicity in Rural Zimbabwe., PMID:39352457
Chemo-sensory loss and FUT2 gene in COVID-19 infected Iraqi dentists., PMID:39241136
RIP3 regulates doxorubicin-induced intestinal mucositis via FUT2-mediated α-1,2-fucosylation., PMID:39180691
Regulation of the Lewis Blood Group Antigen Expression: A Literature Review Supplemented with Computational Analysis., PMID:39135855
Butyrate protects the intestinal barrier by upregulating Fut2 expression via MEK4-JNK signaling pathway activation., PMID:39134757
Fut2 deficiency aggravates chronic colitis through 2-oxindole-AHR mediated cGAS-STING pathway., PMID:38897123
GLT8D2 is a prognostic biomarker and regulator of immune cell infiltration in gastric cancer., PMID:38840920
Fut2 Deficiency Promotes Intestinal Stem Cell Aging by Damaging Mitochondrial Functions via Down-Regulating α1,2-Fucosylation of Asah2 and Npc1., PMID:38550777
Genetic overlap between Alzheimer's disease and immune-mediated diseases: an atlas of shared genetic determinants and biological convergence., PMID:38499654
Genotypes predisposing for celiac disease and autoimmune diabetes and risk of infections in early childhood., PMID:38374560
Correlates of Rotavirus Vaccine Shedding and Seroconversion in a US Cohort of Healthy Infants., PMID:38330312
Identification of biomarker candidates for exfoliative glaucoma from autoimmunity profiling., PMID:38287276
A purified diet affects intestinal epithelial proliferation and barrier functions through gut microbial alterations., PMID:38262747
Host genetic regulation of human gut microbial structural variation., PMID:38172637
Sec1 regulates intestinal mucosal immunity in a mouse model of inflammatory bowel disease., PMID:38066482
Behçet's Disease: A Comprehensive Review on the Role of HLA-B*51, Antigen Presentation, and Inflammatory Cascade., PMID:38003572
Analysis of gut microbiome, host genetics, and plasma metabolites reveals gut microbiome-host interactions in the Japanese population., PMID:37935197
Genetic overlap between Alzheimer's disease and immune-mediated diseases: An atlas of shared genetic determinants and biological convergence., PMID:37841839
Plasma proteomic associations with genetics and health in the UK Biobank., PMID:37794186
Complex effects of sequence variants on lipid levels and coronary artery disease., PMID:37714134
The Influence of Race/Ethnicity on the Transcriptomic Landscape of Uterine Fibroids., PMID:37686244
Expression Profiling along the Murine Intestine: Different Mucosal Protection Systems and Alterations in Tff1-Deficient Animals., PMID:37628863
GWAS of Folate Metabolism With Gene-environment Interaction Analysis Revealed the Possible Role of Lifestyles in the Control of Blood Folate Metabolites in Japanese: The J-MICC Study., PMID:37517992
Reduced susceptibility to COVID-19 associated with ABO blood group and pre-existing anti-A and anti-B antibodies., PMID:37329825
Genome-wide association study of chronic sputum production implicates loci involved in mucus production and infection., PMID:37263751
Histo-blood group antigen profile of Australian Aboriginal children and seropositivity following oral rotavirus vaccination., PMID:37179162
ABO blood types, but not Secretor or Lewis blood types, influence strength of antibody response to Hepatitis B vaccine in Black South African children., PMID:37169653
Phage display sequencing reveals that genetic, environmental, and intrinsic factors influence variation of human antibody epitope repertoire., PMID:37164013
Transcriptome-wide analysis of RNA m6A methylation regulation of muscle development in Queshan Black pigs., PMID:37142996
FUT2 inhibits the EMT and metastasis of colorectal cancer by increasing LRP1 fucosylation., PMID:36973740
Causal associations and shared genetics between hypertension and COVID-19., PMID:36951353
Secretor status of blood group O mothers is associated with development of ABO haemolytic disease in the newborn., PMID:36896479
SARS-CoV-2 infection in children: A 24 months experience with focus on risk factors in a pediatric tertiary care hospital in Milan, Italy., PMID:36873632
Fucosyltransferases Regulated by Fusobacterium Nucleatum and Act as Novel Biomarkers in Colon Adenocarcinoma., PMID:36852302
Intestinal epithelium-specific Fut2 deficiency promotes colorectal cancer through down-regulating fucosylation of MCAM., PMID:36739428
FUT2 promotes the tumorigenicity and metastasis of colorectal cancer cells via the Wnt/β‑catenin pathway., PMID:36734282
FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response., PMID:36724577
Audiologic Measures in an Indigenous Community with A2ML1- and FUT2-Related Otitis Media., PMID:36719978
For research use only. Not for human or drug use.
