Catalog No.
YHG26101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr2-Val255
Predicted molecular weight
30.69 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q10567
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Adaptor protein complex AP-1 subunit beta-1, Clathrin assembly protein complex 1 beta large chain, BAM22, CLAPB2, Adaptor-related protein complex 1 subunit beta-1, AP-1 complex subunit beta-1, Golgi adaptor HA1/AP1 adaptin beta subunit, AP1B1, Beta-adaptin 1, Beta-1-adaptin, ADTB1
Note
For research use only.
Characterization of a new member of the human beta-adaptin gene family from chromosome 22q12, a candidate meningioma gene., PMID:7987321
Structure of the promoter and genomic organization of the human beta'-adaptin gene (BAM22) from chromosome 22q12., PMID:8812422
Characterization of the mouse beta-prime adaptin gene; cDNA sequence, genomic structure, and chromosomal localization., PMID:9271666
Duplications on human chromosome 22 reveal a novel Ret Finger Protein-like gene family with sense and endogenous antisense transcripts., PMID:10508838
The basolateral targeting signal of CD147 (EMMPRIN) consists of a single leucine and is not recognized by retinal pigment epithelium., PMID:15215314
Serial analysis of gene expression in sinusoidal endothelial cells from normal and injured mouse liver., PMID:15464976
Involvement of caspase-cleaved and intact adaptor protein 1 complex in endosomal remodeling in maturing dendritic cells., PMID:16170319
v-SNARE cellubrevin is required for basolateral sorting of AP-1B-dependent cargo in polarized epithelial cells., PMID:17485489
The epithelia-specific membrane trafficking factor AP-1B controls gut immune homeostasis in mice., PMID:21669204
Basolateral EGF receptor sorting regulated by functionally distinct mechanisms in renal epithelial cells., PMID:23205726
Mutations in ap1b1 cause mistargeting of the Na(+)/K(+)-ATPase pump in sensory hair cells., PMID:23593334
Analysis of three μ1-AP1 subunits during zebrafish development., PMID:24123392
Galectin-4-mediated transcytosis of transferrin receptor., PMID:25179596
Basolateral sorting of the Mg²⁺ transporter CNNM4 requires interaction with AP-1A and AP-1B., PMID:25449265
miR-34a as hub of T cell regulation networks., PMID:31311583
Recessive Mutations in AP1B1 Cause Ichthyosis, Deafness, and Photophobia., PMID:31630788
Homozygous Loss-of-Function Mutations in AP1B1, Encoding Beta-1 Subunit of Adaptor-Related Protein Complex 1, Cause MEDNIK-like Syndrome., PMID:31630791
Novel function for AP-1B during cell migration., PMID:32816642
Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions., PMID:32959884
A patient with mental retardation, enteropathy, deafness, peripheral neuropathy, ichthyosis, keratodermia syndrome caused by AP1B1 gene variant., PMID:32969855
MEDNIK-like syndrome due to compound heterozygous mutations in AP1B1., PMID:33349978
Identification of compound heterozygous mutations in AP1B1 leading to the newly described recessive keratitis-ichthyosis-deafness (KIDAR) syndrome., PMID:33452671
Genome-wide association and transcriptome analysis suggests total serum ghrelin to be linked with GFRAL., PMID:33852427
Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal coronaviruses., PMID:34031654
Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal HCoVs., PMID:34075371
Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects., PMID:34445520
Phenotypic spectrum of autosomal recessive Keratitis-Ichthyosis-Deafness Syndrome (KIDAR) due to mutations in AP1B1., PMID:35144013
Proteome-Wide Discovery of Cortical Proteins That May Provide Motor Resilience to Offset the Negative Effects of Pathologies in Older Adults., PMID:35512265
Characterization of 22q12 Microdeletions Causing Position Effect in Rare NF2 Patients with Complex Phenotypes., PMID:36077416
mRNA Capture Sequencing and RT-qPCR for the Detection of Pathognomonic, Novel, and Secondary Fusion Transcripts in FFPE Tissue: A Sarcoma Showcase., PMID:36232302
Osmosensitive transcription factors in the prolactin cell of a euryhaline teleost., PMID:36535574
Identification of candidate genomic regions for egg yolk moisture content based on a genome-wide association study., PMID:36918797
Comprehensive analysis of copper-metabolism-related genes about prognosis and immune microenvironment in osteosarcoma., PMID:37700003
Regulated secretion of mutant p53 negatively affects T lymphocytes in the tumor microenvironment., PMID:37952080
Lysosome-related proteins may have changes in the urinary exosomes of patients with acute gout attack., PMID:39838438
The clathrin adaptor AP1-S1 is associated with immune infiltration and HLA loss, as a potential therapeutic target in lung adenocarcinoma., PMID:40049084
Clinical, biochemical and cell biological characterization of KIDAR syndrome associated with a novel AP1B1 variant., PMID:40101690
For research use only. Not for human or drug use.
