Catalog No.
YHE54301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln103-Leu281
Predicted molecular weight
22.76 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P48023
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Receptor-binding FasL ectodomain, APL, APT1LG1, FasL ICD, Fas antigen ligand, CD178, sFasL, CD95L, APTL, TNFSF6, Apoptosis antigen ligand, SPA, FASLG, FasL, SPPL2A-processed FasL form, Tumor necrosis factor ligand superfamily member 6, Soluble Fas ligand, Fas ligand, CD95 ligand, CD95-L, FASL
[Study of the role of biomarkers in determining the course of non-alcoholic fatty liver disease in children with obesity]., PMID:40418137
Kindlin-2 silencing promoted apoptosis and cell cycle arrest through the fas/FasL pathway in hepatocellular carcinoma., PMID:40392106
The influence of extrinsic apoptosis gene expression on immunological reconstitution of male ART-treated PLHIV., PMID:40102787
Polymorphisms Influence the Expression of the Fas and FasL Genes in COVID-19., PMID:39859379
Exogenous binding immunoglobulin protein (BiP) enhance immune regulatory phenotype in ex-vivo Mtb infected PBMCs stratified based on QuantiFERON response., PMID:39671882
B-cell-Specific Moloney Murine Leukemia Virus Integration Site 1 and Fas Ligand Expression in Colorectal Cancer Progression and Prognosis., PMID:39662015
Changes in the cytotoxic and regulatory functions of NK cells in patients with long-COVID under the influence of the human herpesvirus 6 (pilot study)., PMID:39349781
A Novel Tetravalent CD95/Fas Fusion Protein With Superior CD95L/FasL Antagonism., PMID:39219154
Evaluation of the Effect of Menopausal Status and BMI on Polymorphisms in Fas/Fas L and the Risk of Breast Cancer., PMID:39214844
Analysis of Cytotoxic Granules and Constitutively Produced Extracellular Vesicles from Large Granular Lymphocytic Leukemia Cell Lines., PMID:39195200
Identification of necroptosis-related genes in ankylosing spondylitis by bioinformatics and experimental validation., PMID:39031474
Multiple sclerosis disease activity, a multi-biomarker score of disease activity and response to treatment in multiple sclerosis., PMID:38994359
Endometriotic Tissue-derived Exosomes Downregulate NKG2D-mediated Cytotoxicity and Promote Apoptosis: Mechanisms for Survival of Ectopic Endometrial Tissue in Endometriosis., PMID:38984872
FasL impacts Tgfb signaling in osteoblastic cells., PMID:38810946
Bone marrow CD8+ Trm cells induced by IL-15 and CD16+ monocytes contribute to HSPC destruction in human severe aplastic anemia., PMID:38636890
Synthesis of N-Glycosylated Soluble Fas Ligand., PMID:38363216
A novel triad for the diagnosis of endometriosis, the short anogenital distance combines with high endometrial BCL2 and low endometrial FASL., PMID:38358296
Fas (CD95)/FasL (CD178) system during ageing., PMID:37132427
Role of metalloproteases in the CD95 signaling pathways., PMID:36544756
Cytokine profiles and CD8+ T cells in the occurrence of acute and chronic hepatitis B., PMID:36353632
Fas cell surface death receptor/Fas ligand genetic variants in gastric cancer patients: A case-control study., PMID:36124496
The role of FASL, BCL-2 and BAX polymorphisms in brazilian patients with prostate cancer and benign prostatic hyperplasia., PMID:35988104
"Derived Multiple Allogeneic Protein Paracrine Signaling (d-MAPPS)" Enhances T Cell-Driven Immune Response to Murine Mammary Carcinoma., PMID:35757015
Lamina propria interleukin 17 A aggravates natural killer T-cell activation in autoimmune hepatitis., PMID:35583908
Apigenin Increases Natural Killer Cytotoxicity to Human Hepatocellular Carcinoma Expressing HIF-1α through High Interaction of CD95/CD95L., PMID:35283421
Cleaved CD95L perturbs in vitro macrophages responses to Toxoplasma gondii., PMID:35240289
Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies., PMID:35013338
CAR-NK Cells: From Natural Basis to Design for Kill., PMID:34970253
Long non-coding RNA CASC7 suppresses malignant behaviors of breast cancer by regulating miR-21-5p/FASLG axis., PMID:34889164
Differential cancer risk and survival in Indian oral cancer patients with genic region FAS and FASL polymorphisms., PMID:34753694
Effect of PTPN22, FAS/FASL, IL2RA and CTLA4 genetic polymorphisms on the risk of developing alopecia areata: A systematic review of the literature and meta-analysis., PMID:34735462
NF-κB regulation in maternal immunity during normal and IUGR pregnancies., PMID:34697371
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory., PMID:34644563
Kindlin-2 promoted the progression of keloids through the Smad pathway and Fas/FasL pathway., PMID:34492266
Immune response to intravenous immunoglobulin in patients with Kawasaki disease and MIS-C., PMID:34464357
Naja atra Cardiotoxin 1 Induces the FasL/Fas Death Pathway in Human Leukemia Cells., PMID:34440842
Influence of Galectin-9 Treatment on the Phenotype and Function of NK-92MI Cells in the Presence of Different Serum Supplements., PMID:34439744
Hexokinases inhibit death receptor-dependent apoptosis on the mitochondria., PMID:34385311
Fas -670 A/G polymorphism predicts prognosis of hepatocellular carcinoma after curative resection in Chinese Han population., PMID:34366198
Discriminatory plasma biomarkers predict specific clinical phenotypes of necrotizing soft-tissue infections., PMID:34263738
Triangle of cytokine storm, central nervous system involvement, and viral infection in COVID-19: the role of sFasL and neuropilin-1., PMID:34225390
Mutational analysis of apoptotic genes in familial aggregation of hematological malignancies., PMID:34140154
Cord blood soluble Fas ligand linked to allergic rhinitis and lung function in seven-year-old children., PMID:33879403
Circulating sFasL Levels Predict the Severity and Outcome of Burn Injury: A Prospective Observational Study., PMID:33862353
Cytokine Signature of Dengue Patients at Different Severity of the Disease., PMID:33809042
Pericyte-like cells undergo transcriptional reprogramming and distinct functional adaptations in acute lung injury., PMID:33710674
sFasL-The Key to a Riddle: Immune Responses in Aging Lung and Disease., PMID:33671651
Impact of Fas/Fasl Gene Polymorphisms on Susceptibility Risk and Imatinib Mesylate Treatment Response in Chronic Myeloid Leukaemia Patients., PMID:33639675
Microfluidic Tumor Vasculature Model to Recapitulate an Endothelial Immune Barrier Expressing FasL., PMID:33586426
Association of Plasma Levels of Fas Ligand with Severity and Outcome of Sepsis., PMID:33577245
For research use only. Not for human or drug use.
