Catalog No.
EHE43801
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-His338
Predicted molecular weight
63.37 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P43630
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD158K, MHC class I NK cell receptor, NKAT4, Natural killer-associated transcript 4, KIR3DL2, p70 NK receptor CL-5, CD158k, p70 natural killer cell receptor clone CL-5, CD158 antigen-like family member K, Killer cell immunoglobulin-like receptor 3DL2, NKAT-4
Evaluation of Sézary cell marker expression and cell death behaviour upon in vitro treatment by flow cytometry in Sézary syndrome patients., PMID:39219147
Histopathological Markers for Target Therapies in Primary Cutaneous Lymphomas., PMID:37998391
Clinical Guidelines and New Molecular Targets for Cutaneous Lymphomas., PMID:34681738
CD158k and PD-1 expressions define heterogeneous subtypes of Sezary syndrome., PMID:34570200
[Primary skin lymphomas: Current therapy]., PMID:30709635
Activating and inhibitory receptors on natural killer cells in patients with systemic lupus erythematosis-regulation with interleukin-15., PMID:29023581
Therapeutic Antibodies to KIR3DL2 and Other Target Antigens on Cutaneous T-Cell Lymphomas., PMID:28912774
KIR3DL2 (CD158k) is a potential therapeutic target in primary cutaneous anaplastic large-cell lymphoma., PMID:27037558
Sézary syndrome: old enigmas, new targets., PMID:26972187
Primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma with KIR3DL2 and NKp46 expression in a human immunodeficiency virus carrier., PMID:25407699
CD158k is a reliable marker for diagnosis of Sézary syndrome and reveals an unprecedented heterogeneity of circulating malignant cells., PMID:25158034
Membrane expression of NK receptors CD160 and CD158k contributes to delineate a unique CD4+ T-lymphocyte subset in normal and mycosis fungoides skin., PMID:25044837
Skin-resident CD4+ T cells express NK receptors: lessons from skin pathologies., PMID:25044689
Use of PLS3, Twist, CD158k/KIR3DL2, and NKp46 gene expression combination for reliable Sézary syndrome diagnosis., PMID:23429988
New perspectives on the ligands and function of the killer cell immunoglobulin-like receptor KIR3DL2 in health and disease., PMID:23162554
CD158k/KIR3DL2 and NKp46 are frequently expressed in transformed mycosis fungoides., PMID:22621189
[New developments in Sézary syndrome]., PMID:22225740
Expression and function of the natural cytotoxicity receptor NKp46 on circulating malignant CD4+ T lymphocytes of Sézary syndrome patients., PMID:21191411
Absolute CD3+ CD158k+ lymphocyte count is reliable and more sensitive than cytomorphology to evaluate blood tumour burden in Sézary syndrome., PMID:19681856
NKG2D ligands expression and NKG2D-mediated NK activity in Sezary patients., PMID:18754036
CD158k/KIR3DL2 is a useful marker for identifying neoplastic T-cells in Sézary syndrome by flow cytometry., PMID:18061949
CD158K/KIR3DL2 transcript detection in lesional skin of patients with erythroderma is a tool for the diagnosis of Sézary syndrome., PMID:17703174
[Epidermotropic T cell lymphomas as models for tumor progression]., PMID:16457762
Significance of circulating T-cell clones in Sezary syndrome., PMID:16418328
T-cell large granular lymphocyte leukemias have multiple phenotypic abnormalities involving pan-T-cell antigens and receptors for MHC molecules., PMID:16416744
SC5 mAb represents a unique tool for the detection of extracellular vimentin as a specific marker of Sezary cells., PMID:16365461
CD158k/KIR3DL2 is a new phenotypic marker of Sezary cells: relevance for the diagnosis and follow-up of Sezary syndrome., PMID:15086570
Polymorphic expression of CD158k/p140/KIR3DL2 in Sézary patients., PMID:12529298
Engagement of ILT2/CD85j in Sézary syndrome cells inhibits their CD3/TCR signaling., PMID:12130517
For research use only. Not for human or drug use.
