Catalog No.
EHE43601
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-His245
Predicted molecular weight
53.27 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P43628
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NKAT2b, KIR2DL3, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158 antigen-like family member B2, MHC class I NK cell receptor, KIR-023GB, Killer inhibitory receptor cl 2-3, p58 NK receptor CL-6, CD158b2, Killer cell immunoglobulin-like receptor 2DL3, Natural killer-associated transcript 2, CD158B2, KIRCL23, NKAT-2, NKAT2a, NKAT2
Discovery of the novel KIR2DL3*00111 allele in a Chinese Han individual., PMID:38887878
A single nucleotide substitution in exon 5 generated the novel KIR2DL3*00112 allele., PMID:38837671
The novel KIR2DL3*037 allele, identified by Sanger dideoxy nucleotide sequencing in a Chinese individual., PMID:38837624
Association study between killer immunoglobulin-like receptor polymorphisms and susceptibility to COVID-19 disease: a systematic review and meta-analysis., PMID:37874432
Antiviral prophylaxis, male sex, and killer immunoglobulin-like receptor KIR2DL3 as markers for stratifying the risk of BK polyomavirus-associated nephropathy in kidney transplant recipients., PMID:36018060
Clinical Impact of KIR2DS3 and KIR2DL3 Genes in Neuroblastoma Patients., PMID:35537400
Donor NK and T Cells in the Periphery of Lung Transplant Recipients Contain High Frequencies of Killer Cell Immunoglobulin-Like Receptor-Positive Subsets., PMID:34966390
Increased Susceptibility of the CD57- NK Cells Expressing KIR2DL2/3 and NKG2C to iCasp9 Gene Retroviral Transduction and the Relationships with Proliferative Potential, Activation Degree, and Death Induction Response., PMID:34948123
Significance of inhibitory maternal killer-cell immunoglobulin-like receptor (KIR) and fetal KIR ligand genotype combinations in placenta related obstetric complications., PMID:34607283
Deciphering the biology of KIR2DL3+ T lymphocytes that are associated to relapse in haploidentical HSCT., PMID:34349169
Missing Self-Induced Microvascular Rejection of Kidney Allografts: A Population-Based Study., PMID:34301794
Natural Killer Cells Generated From Human Induced Pluripotent Stem Cells Mature to CD56brightCD16+NKp80+/-In-Vitro and Express KIR2DL2/DL3 and KIR3DL1., PMID:34017328
Natural killer cell receptor variants and chronic hepatitis B virus infection in the Vietnamese population., PMID:32422377
The immunoglobulin γ marker 17 allotype and KIR/HLA genes prevent the development of chronic hepatitis B in humans., PMID:31613998
The Education of NK Cells Determines Their Responsiveness to Autologous HIV-Infected CD4 T Cells., PMID:31511383
Imbalance of Genes Encoding Natural Killer Immunoglobulin-Like Receptors and Human Leukocyte Antigen in Patients With Biliary Cancer., PMID:31229495
Differential contribution of education through KIR2DL1, KIR2DL3, and KIR3DL1 to antibody-dependent (AD) NK cell activation and ADCC., PMID:30698860
Impact of HLA Allele-KIR Pairs on HIV Clinical Outcome in South Africa., PMID:30520960
Stable Frequencies of HLA-C*03:04/Peptide-Binding KIR2DL2/3+ Natural Killer Cells Following Vaccination., PMID:30386333
A novel antibody combination to identify KIR2DS2high natural killer cells in KIR2DL3/L2/S2 heterozygous donors., PMID:30381896
Novel multiplex PCR-SSP method for centromeric KIR allele discrimination., PMID:30291273
KIR downregulation by IL-12/15/18 unleashes human NK cells from KIR/HLA-I inhibition and enhances killing of tumor cells., PMID:29105756
Enhanced natural killer cell activity is found in exposed uninfected recipients of hepatitis C-contaminated blood., PMID:29063663
HIV-1-Mediated Downmodulation of HLA-C Impacts Target Cell Recognition and Antiviral Activity of NK Cells., PMID:28704647
The role of KIR and HLA interactions in pregnancy complications., PMID:28695287
Expression of Natural Killer Cell Inhibitory Receptors is Associated with Significant Liver Injury in Chronic Hepatitis C in Children., PMID:28611271
KIR2DL3 and the KIR ligand groups HLA-A-Bw4 and HLA-C2 predict the outcome of hepatitis B virus infection., PMID:28211154
KIR 2D (L1, L3, L4, S4) and KIR 3DL1 protein expression in non-small cell lung cancer., PMID:27893413
Ocular toxoplasmosis: susceptibility in respect to the genes encoding the KIR receptors and their HLA class I ligands., PMID:27827450
NK Cells Expressing the Inhibitory Killer Immunoglobulin-Like Receptors (iKIR) KIR2DL1, KIR2DL3 and KIR3DL1 Are Less Likely to Be CD16+ than Their iKIR Negative Counterparts., PMID:27732638
The differential impact of natural killer (NK) cell education via KIR2DL3 and KIR3DL1 on CCL4 secretion in the context of in-vitro HIV infection., PMID:27506421
A multifaceted computational report on the variants effect on KIR2DL3 and IFNL3 candidate gene in HCV clearance., PMID:27461217
KIR2DL2/2DL3-E(35) alleles are functionally stronger than -Q(35) alleles., PMID:27030405
The investigation of killer cell immunoglobulin-like receptor genotyping in patients with systemic lupus erytematosus and systemic sclerosis., PMID:26960450
Exploring the Role of Killer Cell Immunoglobulin-Like Receptors and Their HLA Class I Ligands in Autoimmune Hepatitis., PMID:26744892
Significant association of the KIR2DL3/HLA-C1 genotype with susceptibility to Crohn's disease., PMID:26542067
KIR2DL3 and KIR2DL1 show similar impact on licensing of human NK cells., PMID:26467237
NK Cell Proliferation Induced by IL-15 Transpresentation Is Negatively Regulated by Inhibitory Receptors., PMID:26453750
Allelic polymorphism of KIR2DL2/2DL3 in a southern Chinese population., PMID:26423800
The effect of KIR2D-HLA-C receptor-ligand interactions on clinical outcome in a HIV-1 CRF01_AE-infected Thai population., PMID:26372271
Tissue-Specific Education of Decidual NK Cells., PMID:26320253
Polymorphic HLA-C Receptors Balance the Functional Characteristics of KIR Haplotypes., PMID:26311903
Diversity in KIR gene repertoire in HIV-1 exposed infected and uninfected infants: A study from India., PMID:26255774
The role of KIR2DL3/HLA-C*0802 in Brazilian patients with rheumatoid vasculitis., PMID:26106958
Killer immunoglobulin receptor genes and their HLA-C ligand are associated with Type 1 diabetes in an Eastern Indian population., PMID:26031759
Increased co-expression of the natural killer cell receptor NKG2D and further natural killer cell receptors on CD4⁺ T cells in granulomatosis with polyangiitis., PMID:26016770
A novel KIR2DL3 variant allele, KIR2DL3*032, which has arisen by a missense mutation in codon 231., PMID:25626612
ERAP1 regulates natural killer cell function by controlling the engagement of inhibitory receptors., PMID:25592150
Killer cell immunoglobulin receptor profile on CD4(+) CD28(-) T cells and their pathogenic role in non-dialysis-dependent and dialysis-dependent chronic kidney disease patients., PMID:25484131
Enrichment of CD56(dim)KIR + CD57 + highly cytotoxic NK cells in tumour-infiltrated lymph nodes of melanoma patients., PMID:25472612
For research use only. Not for human or drug use.
