Catalog No.
EHE43401
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-His245
Predicted molecular weight
28.03 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P43626
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD158 antigen-like family member A, KIR2DL1, Killer cell immunoglobulin-like receptor 2DL1, Natural killer-associated transcript 1, NKAT-1, MHC class I NK cell receptor, CD158A, p58 natural killer cell receptor clones CL-42/47.11, CD158a, p58.1 MHC class-I-specific NK receptor, NKAT1, p58 NK receptor CL-42/47.11
Isolation and characterization of primary NK cells and the enrichment of the KIR2DL1+ population., PMID:39919843
Recognition of Novel KIR2DL1*0040135, KIR2DL1*112, KIR2DL1*0040136, KIR3DL1*0010122 Alleles From India., PMID:39721044
Characterisation of the novel KIR2DL1*00308 allele identified in a Chinese Han individual., PMID:39247980
KIR2DL1 gene is a surrogate marker of protection against infection-related hospitalization among HIV-1 unexposed versus exposed uninfected infants in Cameroon., PMID:39090586
The role of TIM3+ NK and TIM3- NK cells in the immune pathogenesis of severe aplastic anemia., PMID:38525441
Donor KIR2DL1 Allelic Polymorphism Influences Posthematopoietic Progenitor Cell Transplantation Outcomes in the T Cell Depleted and Reduced Intensity Conditioning Setting., PMID:38369017
KIR2DS1 and KIR2DL1-C245 Dominantly Repress NK Cell Degranulation Triggered by Monoclonal or Bispecific Antibodies, whereas Education by Uptuning Inhibitory Killer Ig-related Receptors Exerts No Advantage in Ab-dependent Cellular Cytotoxicity., PMID:38240527
Immune system cells modulation in patients with reproductive issues: A systematic review approach., PMID:37962966
Functional TRPA1 Channels Regulate CD56dimCD16+ NK Cell Cytotoxicity against Tumor Cells., PMID:37834182
The KIR2DL1 intermediate upstream element participates in gene activation., PMID:37801092
NK cells from COVID-19 positive patients exhibit enhanced cytotoxic activity upon NKG2A and KIR2DL1 blockade., PMID:37483595
Establishing NK-Cell Receptor Restriction by Flow Cytometry and Detecting Potential NK-Cell Clones of Uncertain Significance., PMID:37385341
γδ-T cell with high toxic potential was associated with recurrent miscarriage., PMID:37382173
Dynamic changes of phenotype and function of natural killer cells in peripheral blood before and after thermal ablation of hepatitis B associated hepatocellular carcinoma and their correlation with tumor recurrence., PMID:37254046
Uterine NK cells underexpress KIR2DL1/S1 and LILRB1 in reproductive failure., PMID:36713400
Natural Killer Cell Receptors and Endometriosis: A Systematic Review., PMID:36613776
Co-expression of activating and inhibitory receptors on peritoneal fluid NK cells in women with endometriosis., PMID:36442371
Compromised activity of natural killer cells in diffuse large b-cell lymphoma is related to lymphoma-induced modification of their surface receptor expression., PMID:36048214
4-1BB antibody enhances cytotoxic activity of natural killer cells against prostate cancer cells via NKG2D agonist combined with IL-27., PMID:35852136
Reduced Expression of Natural Killer Cell-Related Activating Receptors by Peripheral Blood Mononuclear Cells from Patients with Breast Cancer and Their Improvement by Zoledronic Acid., PMID:35633551
Characterization of KIR+ NK cell subsets with a monoclonal antibody selectively recognizing KIR2DL1 and blocking the specific interaction with HLA-C., PMID:35439359
Epitope characterization of a monoclonal antibody that selectively recognizes KIR2DL1 allotypes., PMID:35411634
CD158a+ /CD158b+ NK cell imbalance correlates with hypertension in patients with pre-eclampsia., PMID:35253311
Expression of Killer Immunoglobulin Receptor Genes among HIV-Infected Individuals with Non-AIDS Comorbidities., PMID:35071606
Clinical impact of Fn-induced high expression of KIR2DL1 in CD8 T lymphocytes in oesophageal squamous cell carcinoma., PMID:34935568
Expression of immune-related genes as prognostic biomarkers for the assessment of osteosarcoma clinical outcomes., PMID:34916564
Immunomonitoring of Stage IV Relapsed Neuroblastoma Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplantation and Subsequent GD2 (ch14.18/CHO) Antibody Treatment., PMID:34367149
Physiological Fitness and the Pathophysiology of Chronic Lymphocytic Leukemia (CLL)., PMID:34064804
Differences in the Expression of KIR, ILT Inhibitory Receptors, and VEGF Production in the Induced Decidual NK Cell Cultures of Fertile and RPL Women., PMID:33997038
Natural Killer Cell Subpopulations and Inhibitory Receptor Dynamics in Myelodysplastic Syndromes and Acute Myeloid Leukemia., PMID:33986753
Lack of association of KIR2DL1-R245 and KIR2DL1-C245 with HIV-1 control in black South Africans with HLA-C2., PMID:33906789
HLA-C*17 in COVID-19 patients: Hints for associations with severe clinical outcome and cardiovascular risk., PMID:33905752
Proposal for the designation of the natural killer antigens-positive γδ T-cell subset as γδ NKT-cells: nomenclature based on immunoprofile., PMID:33840040
NKG2D as a Cell Surface Marker on γδ-T Cells for Predicting Pregnancy Outcomes in Patients With Unexplained Repeated Implantation Failure., PMID:33777016
Generation of multiple iPSC clones from a male schizophrenia patient carrying de novo mutations in genes KHSRP, LRRC7, and KIR2DL1, and his parents., PMID:33503521
Influence of HLA-C environment on the spontaneous clearance of hepatitis C in European HIV-HCV co-infected individuals., PMID:33314121
The combinatorial diversity of KIR and HLA class I allotypes in Peninsular Malaysia., PMID:33283280
Effect of interleukins (IL-2, IL-15, IL-18) on receptors activation and cytotoxic activity of natural killer cells in breast cancer cell., PMID:33163049
Single Nucleotide Polymorphism in KIR2DL1 Is Associated With HLA-C Expression in Global Populations., PMID:32983108
Activation status of CD56dim natural killer cells is associated with disease activity of patients with systemic lupus erythematosus., PMID:32797360
Association of killer-cell immunoglobulin-like receptor genes with acute myelogenous leukaemia., PMID:32767509
Gene expression analysis of activating and inhibitory receptors of natural killer cells in patients with acute myeloblastic leukemia., PMID:32592956
Tuning of human NK cells by endogenous HLA-C expression., PMID:32219494
Systemic β-Adrenergic Receptor Activation Augments the ex vivo Expansion and Anti-Tumor Activity of Vγ9Vδ2 T-Cells., PMID:32038628
A simple method for in vitro preparation of natural killer cells from cord blood., PMID:31752805
Availability of NK cell expansion agent combined with recombinant IL‑2 and IL‑15 stimulation on the expansion and high‑purity of NK cells in patients with immune‑related pancytopenia in vitro., PMID:31545423
KIR Polymorphism Modulates the Size of the Adaptive NK Cell Pool in Human Cytomegalovirus-Infected Individuals., PMID:31519864
The Education of NK Cells Determines Their Responsiveness to Autologous HIV-Infected CD4 T Cells., PMID:31511383
High Activation of γδ T Cells and the γδ2pos T-Cell Subset Is Associated With the Onset of Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome, ANRS 12153 CAPRI NK., PMID:31507608
NK Response Correlates with HIV Decrease in Pegylated IFN-α2a-Treated Antiretroviral Therapy-Suppressed Subjects., PMID:31253727
For research use only. Not for human or drug use.
