Catalog No.
YHK02501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys227
Predicted molecular weight
27.75 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UEY8
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Adducin-like protein 70, ADDL, ADD3, Gamma-adducin
Note
For research use only.
Common genetic variants regulating ADD3 gene expression alter biliary atresia risk., PMID:23872602
Replication of a GWAS signal in a Caucasian population implicates ADD3 in susceptibility to biliary atresia., PMID:24104524
Association between single nucleotide polymorphisms in the ADD3 gene and susceptibility to biliary atresia., PMID:25285724
Genome-wide association studies in biliary atresia., PMID:25963027
Genetic contributors and modifiers of biliary atresia., PMID:26045276
Co-expression of Cytoskeletal Protein Adducin 3 and CD133 in Neurospheres and a Temozolomide-resistant Subclone of Glioblastoma., PMID:26637861
ADDing a piece to the puzzle of cognition in schizophrenia., PMID:26723519
Alpha Adducin G460T Variant is a Risk Factor for Hypertension in Tunisian Population., PMID:27349000
Loss of a Candidate Biliary Atresia Susceptibility Gene, add3a, Causes Biliary Developmental Defects in Zebrafish., PMID:27526058
Knockdown of Add3 impairs the myogenic response of renal afferent arterioles and middle cerebral arteries., PMID:27927653
Characterisation of the genomic landscape of CRLF2-rearranged acute lymphoblastic leukemia., PMID:28033648
Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder., PMID:28072414
Adducin family proteins possess different nuclear export potentials., PMID:28490361
Downregulation of microRNA-145 may contribute to liver fibrosis in biliary atresia by targeting ADD3., PMID:28902846
Gene expression profiling of acute myeloid leukemia samples from adult patients with AML-M1 and -M2 through boutique microarrays, real-time PCR and droplet digital PCR., PMID:29286103
Single nucleotide polymorphisms within Adducin 3 and Adducin 3 antisense RNA1 genes are associated with biliary atresia in Thai infants., PMID:29508064
The intragenic epistatic association of ADD3 with biliary atresia in Southern Han Chinese population., PMID:29685956
A homozygous KAT2B variant modulates the clinical phenotype of ADD3 deficiency in humans and flies., PMID:29768408
A Review on Adducin from Functional to Pathological Mechanisms: Future Direction in Cancer., PMID:29862265
Transcription factor GATA4 associates with mesenchymal-like gene expression in human hepatoblastoma cells., PMID:30074440
Application of Weighted Gene Co-Expression Network Analysis to Explore the Key Genes in Alzheimer's Disease., PMID:30124448
Adducins inhibit lung cancer cell migration through mechanisms involving regulation of cell-matrix adhesion and cadherin-11 expression., PMID:30290240
Biliary Atresia Relevant Human Induced Pluripotent Stem Cells Recapitulate Key Disease Features in a Dish., PMID:30358741
[Chronic phosphoproteomic in temporal lobe epilepsy mouse models induced by kainic acid]., PMID:30996354
A Review of the Epidemiological Evidence for Adducin Family Gene Polymorphisms and Hypertension., PMID:31275642
Loss of cytoskeleton protein ADD3 promotes tumor growth and angiogenesis in glioblastoma multiforme., PMID:31958485
A Mutation in γ-Adducin Impairs Autoregulation of Renal Blood Flow and Promotes the Development of Kidney Disease., PMID:32029431
Association of common variation in ADD3 and GPC1 with biliary atresia susceptibility., PMID:32315284
Impaired renal hemodynamics and glomerular hyperfiltration contribute to hypertension-induced renal injury., PMID:32830539
Identification of New Genetic Clusters in Glioblastoma Multiforme: EGFR Status and ADD3 Losses Influence Prognosis., PMID:33172155
QKI-5 regulates the alternative splicing of cytoskeletal gene ADD3 in lung cancer., PMID:33196842
Role of γ-adducin in actin cytoskeleton rearrangements in podocyte pathophysiology., PMID:33308016
Knockout of γ-Adducin Promotes NG-Nitro-L-Arginine-Methyl-Ester-Induced Hypertensive Renal Injury., PMID:33414130
ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion., PMID:34009296
Several Fusion Genes Identified in a Spermatic Cord Leiomyoma With Rearrangements of Chromosome Arms 3p and 21q., PMID:34183386
Comprehensive transcriptome-wide analysis of spliceopathy correction of myotonic dystrophy using CRISPR-Cas9 in iPSCs-derived cardiomyocytes., PMID:34371182
Posttranscriptional inhibition of γ-adducin promotes the proliferation and migration of osteosarcoma cells., PMID:34632867
The adducin saga: pleiotropic genomic targets for precision medicine in human hypertension-vascular, renal, and cognitive diseases., PMID:34859687
Role of long non-coding RNA-adducin 3 antisense RNA1 in liver fibrosis of biliary atresia., PMID:35246014
Hereditary spastic paraparesis presenting as cerebral palsy due to ADD3 variant with mechanistic insight provided by a Drosophila γ-adducin model., PMID:36046955
Impact of EFEMP1 on the survival outcome of biliary atresia in Thai infants., PMID:36114336
The correlation between rs2501577 gene polymorphism and biliary atresia: a systematic review and meta-analysis., PMID:37248361
Knockdown of long noncoding RNA SAN rejuvenates aged adipose-derived stem cells via miR-143-3p/ADD3 axis., PMID:37605290
Contribution of ADD3 and the HLA Genes to Biliary Atresia Risk in Chinese., PMID:37834180
IDH1R132H mutation increases radiotherapy efficacy and a 4-gene radiotherapy-related signature of WHO grade 4 gliomas., PMID:37952042
Prediction significance of autophagy-related genes in survival probability and drug resistance in diffuse large B-cell lymphoma., PMID:38240686
Validating core therapeutic targets for osteoporosis treatment based on integrating network pharmacology and informatics., PMID:38364892
Construction of a prognostic model with CAFs for predicting the prognosis and immunotherapeutic response of lung squamous cell carcinoma., PMID:38520221
Identification of diagnostic biomarkers and immune cell profiles associated with COPD integrated bioinformatics and machine learning., PMID:39344484
Proteomic analysis of carotid artery plaques with and without vulnerable features on magnetic resonance angiography with vessel wall imaging: a pilot study., PMID:40034248
For research use only. Not for human or drug use.
