Catalog No.
YHJ97901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys11-Leu314
Predicted molecular weight
35.79 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q93088
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Betaine--homocysteine S-methyltransferase 1, BHMT
Blockade of the estrogen receptor alpha-pregnane X receptor axis protects ovariectomized mice against ethanol-induced hepatotoxicity., PMID:40381698
The complex role of glycine N-methyltransferase in metabolism-a review., PMID:40025311
Betaine inhibits the stem cell-like properties of hepatocellular carcinoma by activating autophagy via SAM/m6A/YTHDF1-mediated enhancement on ATG3 stability., PMID:39897540
Betaine-homocysteine methyltransferase attenuates liver ischemia-reperfusion injury by targeting TAK1., PMID:39854060
Proteomic analysis of plasma and duodenal tissue in celiac disease patients reveals potential noninvasive diagnostic biomarkers., PMID:39622892
Integration of epigenomic and transcriptomic profiling uncovers EZH2 target genes linked to cysteine metabolism in hepatocellular carcinoma., PMID:39516467
LncRNA H19 promoted alcohol-associated liver disease through dysregulation of alternative splicing and methionine metabolism., PMID:39364651
Integrated ubiquitomics characterization of hepatocellular carcinomas., PMID:39348425
Alterations in one‑carbon metabolism and protein synthesis signals due to methionine supplementation and lipopolysaccharide challenge in Holstein fetal liver explants., PMID:39191197
Betaine alleviates nonalcoholic fatty liver disease (NAFLD) via a manner involving BHMT/FTO/m6A/ PGC1α signaling., PMID:39154792
Plantaginis Semen Ameliorates Hyperuricemia Induced by Potassium Oxonate., PMID:39126116
Ribosomal modification protein rimK-like family member A activates betaine-homocysteine S-methyltransferase 1 to ameliorate hepatic steatosis., PMID:39117631
Congenital Heart Disease and Genetic Changes in Folate/Methionine Cycles., PMID:39062651
Effect of Dietary Crude Protein and Apparent Metabolizable Energy Levels on Growth Performance, Nitrogen Utilization, Serum Parameter, Protein Synthesis, and Amino Acid Metabolism of 1- to 10-Day-Old Male Broilers., PMID:39000537
Regulation of Betaine Homocysteine Methyltransferase by Liver Receptor Homolog-1 in the Methionine Cycle., PMID:38804232
Deficiency of betaine-homocysteine methyltransferase activates glucose-6-phosphate dehydrogenase (G6PD) by decreasing arginine methylation of G6PD in hepatocellular carcinogenesis., PMID:38679670
Parental betaine supplementation promotes gosling growth with epigenetic modulation of IGF gene family in the liver., PMID:38483185
High-fat diet induced obesity promotes inflammation, oxidative stress, and hepatotoxicity in female FVB/N mice., PMID:38183321
Dietary Supplementation with Pomegranate and Onion Affects Lipid and Protein Oxidation in the Breast Meat, Thigh, and Liver, Cellular Stress Protein Responses, and Gene Expression of Liver Enzymes Involved in Protein Synthesis in Broilers., PMID:37893762
Intermediate metabolites and molecular correlates of one‑carbon and nutrient metabolism differ in tissues from Holstein fetuses., PMID:37678126
Correlation of toxicities and efficacies of pemetrexed with clinical factors and single-nucleotide polymorphisms: a prospective observational study., PMID:37633908
Spic regulates one-carbon metabolism and histone methylation in ground-state pluripotency., PMID:37595034
Transcriptome and metabolome analyses reveal gender-specific expression genes in sea cucumber (Holothuria leucospilota)., PMID:37591053
Body condition prepartum and its association with term placentome nutrient transporters, one‑carbon metabolism pathway activity, and intermediate metabolites in Holstein cows., PMID:37516040
SDC1-TGM2-FLOT1-BHMT complex determines radiosensitivity of glioblastoma by influencing the fusion of autophagosomes with lysosomes., PMID:37441590
Genetic Targeting of dSAMTOR, A Negative dTORC1 Regulator, during Drosophila Aging: A Tissue-Specific Pathology., PMID:37298625
Effect of source and amount of rumen-protected choline on hepatic metabolism during induction of fatty liver in dairy cows., PMID:37210357
BHMT polymorphism and susceptibility to PTE in Chinese patients., PMID:37203835
Betaine-homocysteine methyltransferase promotes adipocyte commitment and insulin resistance via p38 MAPK/Smad signaling., PMID:37203331
Bushen-Yizhi formula ameliorates mitochondrial dysfunction and oxidative stress via AMPK/Sirt1 signaling pathway in D-gal-induced aging rats., PMID:37170155
Vegetable Oil-Peroxidation Product 'Hydroxynonenal' Causes Hepatocyte Injury and Steatosis via Hsp70.1 and BHMT Disorders in the Monkey Liver., PMID:37111122
Metabolomic and Proteomic Profiling of Porcine Intestinal Epithelial Cells Infected with Porcine Epidemic Diarrhea Virus., PMID:36982147
A new view on functions of the lysine demalonylase activity of SIRT5., PMID:36921688
Mutation in Smek2 regulating hepatic glucose metabolism causes hypersarcosinemia and hyperhomocysteinemia in rats., PMID:36810603
Hepatic oleate regulates one-carbon metabolism during high carbohydrate feeding., PMID:36791500
Homocysteine-induced endoplasmic reticulum stress activates FGF21 and is associated with browning and atrophy of white adipose tissue in Bhmt knockout mice., PMID:36755585
Key genes for arsenobetaine synthesis in marine medaka (Oryzias melastigma) by transcriptomics., PMID:36395554
Metalloproteomic approach to liver tissue of rats exposed to mercury., PMID:36375612
Pathogenesis of Alcohol-Associated Liver Disease., PMID:36340300
Profiling the Influence of Gene Variants Related to Folate-Mediated One-Carbon Metabolism on the Outcome of In Vitro Fertilization (IVF) with Donor Oocytes in Recipients Receiving Folic Acid Fortification., PMID:36232598
Association and Interaction Effect of BHMT Gene Polymorphisms and Maternal Dietary Habits with Ventricular Septal Defect in Offspring., PMID:35956270
How Different Dietary Methionine Sources Could Modulate the Hepatic Metabolism in Rainbow Trout?, PMID:35877447
Association of Maternal Betaine-Homocysteine Methyltransferase (BHMT) and BHMT2 Genes Polymorphisms with Congenital Heart Disease in Offspring., PMID:35835902
Repair mechanism of Wuwei Fuzheng Yijing formula in di-2-ethylhexyl phthalate-induced sperm DNA fragmentation in mice., PMID:35797467
Effects of dietary restriction on hepatic sulfur-containing amino acid metabolism and its significance in acetaminophen-induced liver injury., PMID:35697284
Betaine Alleviates High-Fat Diet-Induced Disruptionof Hepatic Lipid and Iron Homeostasis in Mice., PMID:35682942
Increased homocysteine regulated by androgen activates autophagy by suppressing the mammalian target of rapamycin pathway in the granulosa cells of polycystic ovary syndrome mice., PMID:35485387
The betaine-dependent remethylation pathway is a homocysteine metabolism pathway associated with the carnivorous feeding habits of spiders., PMID:34647692
Are we getting closer to the role of one-carbon metabolism and methylation in the onset of Down syndrome?, PMID:34613586
One-carbon metabolism and global DNA methylation in mothers of individuals with Down syndrome., PMID:34410622
For research use only. Not for human or drug use.
