Catalog No.
YHJ92301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro34-Lys277
Predicted molecular weight
29.23 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y6Z7
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Collectin liver protein 1, CL-34, CL-L1, Collectin-34, COLEC10, CLL1, Collectin-10
COLEC10: A potential tumor suppressor and prognostic biomarker in hepatocellular carcinoma through modulation of EMT and PI3K-AKT pathways., PMID:40026364
HCC control by lycorine-based restraining of the MiR-224-5p/COLEC10 axis., PMID:39495851
Clinical associations of complement-activating collectins, collectin-10, collectin-11 and mannose-binding lectin in preterm neonates., PMID:39464884
COLEC10 inhibits the stemness of hepatocellular carcinoma by suppressing the activity of β-catenin signaling., PMID:39080215
Revealing novel genomic insights and therapeutic targets for juvenile idiopathic arthritis through omics., PMID:38317060
The osteoporosis susceptibility SNP rs188303909 at 2q14.2 regulates EN1 expression by modulating DNA methylation and E2F6 binding., PMID:38153509
The C-type lectin COLEC10 is predominantly produced by hepatic stellate cells and involved in the pathogenesis of liver fibrosis., PMID:38036508
'A child with Malpuech-Michels-Mingarelli-Carnevale syndrome and ADHD and major depressive disorder'., PMID:37463393
COLEC10 Induces Endoplasmic Reticulum Stress by Occupying GRP78 and Inhibits Hepatocellular Carcinoma., PMID:36925047
3MC syndrome: molecular findings in previously reported and milder patients expand the natural history and phenotypic spectrum., PMID:36503917
Expanding the phenotypic spectrum of COLEC10-Related 3MC syndrome: A glimpse into COLEC10-Related 3MC syndrome in the Ashkenazi Jewish population., PMID:35943032
Germline rare variants of lectin pathway genes predispose to asymptomatic SARS-CoV-2 infection in elderly individuals., PMID:35511137
Serum Proteomic Analysis by Tandem Mass Tag-Based Quantitative Proteomics in Pediatric Obstructive Sleep Apnea., PMID:35480887
A new finding in the key prognosis-related proto-oncogene FYN in hepatocellular carcinoma based on the WGCNA hub-gene screening trategy., PMID:35397600
A novel COLEC10 mutation in a child with 3MC syndrome., PMID:34740859
Whole-exome sequencing identified first homozygous frameshift variant in the COLEC10 gene in an Iranian patient causing 3MC syndrome type 3., PMID:34636477
MASP1-related 3MC syndrome in a patient from Turkey., PMID:33765348
MiR-452-5p mediates the proliferation, migration and invasion of hepatocellular carcinoma cells via targeting COLEC10., PMID:33565325
Exploring the transcriptomic network of multi-ligand scavenger receptor Stabilin-1- and Stabilin-2-deficient liver sinusoidal endothelial cells., PMID:33130055
Association of Polymorphisms of MASP1/3, COLEC10, and COLEC11 Genes with 3MC Syndrome., PMID:32751929
Sacral protuberance with cleft lip and palate: Prenatal presentation of 3MC syndrome., PMID:32441374
Identification of cancer stem cell characteristics in liver hepatocellular carcinoma by WGCNA analysis of transcriptome stemness index., PMID:32311840
Complement lectin pathway protein levels reflect disease activity in juvenile idiopathic arthritis: a longitudinal study of the Nordic JIA cohort., PMID:31500626
Novel Monoclonal Antibodies Against Native Human Collectin L1, Using the Heteromeric Complex CL-LK as Immunogen., PMID:30362927
Decreased expression of COLEC10 predicts poor overall survival in patients with hepatocellular carcinoma., PMID:30122986
CL-L1 and CL-K1 Exhibit Widespread Tissue Distribution With High and Co-Localized Expression in Secretory Epithelia and Mucosa., PMID:30108587
Biallelic intragenic deletion in MASP1 in an adult female with 3MC syndrome., PMID:29407414
COLEC10 is mutated in 3MC patients and regulates early craniofacial development., PMID:28301481
Collectin Liver 1 and Collectin Kidney 1 of the Lectin Complement Pathway Are Associated With Mortality After Kidney Transplantation., PMID:27341702
The pattern recognition molecule collectin-L1 in critically ill children., PMID:27057739
Developmental regulation of chicken surfactant protein A and its localization in lung., PMID:26976230
Collectin liver 1 and collectin kidney 1 and other complement-associated pattern recognition molecules in systemic lupus erythematosus., PMID:26154564
Annotation and genetic diversity of the chicken collagenous lectins., PMID:25721364
Genetic variation of COLEC10 and COLEC11 and association with serum levels of collectin liver 1 (CL-L1) and collectin kidney 1 (CL-K1)., PMID:25710878
Circulating mannan-binding lectin, M-, L-, H-ficolin and collectin-liver-1 levels in patients with acute liver failure., PMID:25203057
Changes in the levels of mannan-binding lectin and ficolins during head-down tilted bed rest., PMID:25199121
Heteromeric complexes of native collectin kidney 1 and collectin liver 1 are found in the circulation with MASPs and activate the complement system., PMID:24174618
Investigations on collectin liver 1., PMID:23814060
[Collectin family as a host defense lectin]., PMID:14978968
Molecular cloning of mouse collectin liver 1., PMID:12450124
Molecular cloning of a novel human collectin from liver (CL-L1)., PMID:10224141
For research use only. Not for human or drug use.
