Catalog No.
YHJ92001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Cys5176-Ala5344
Predicted molecular weight
20.23 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y6R7
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IgGFc-binding protein, Fcgamma-binding protein antigen, FCGBP, FcgammaBP
Association of Fc gamma-binding protein rs1464897604 polymorphism with bronchiolitis obliterans syndrome in lung transplant recipients., PMID:40441397
Screening of Fecal Bacteroides Strains and Discovery of Bacteroides eggerthii S13-F8 with Protective Effects Against Chemotherapy-Induced Diarrhea., PMID:40423879
Combining Mass Spectrometry with Machine Learning to Identify Novel Protein Signatures: The Example of Multisystem Inflammatory Syndrome in Children., PMID:40313298
Hypobaric hypoxia exposure impairs colonic goblet cell subpopulation via the HIF-1α signaling pathway., PMID:40132123
Fc fragment of IgG binding protein suppresses tumor growth by stabilizing wild type P53 in colorectal cancer cells., PMID:40108539
Identification and Validation of Four Serum Biomarkers With Optimal Diagnostic and Prognostic Potential for Gastric Cancer Based on Machine Learning Algorithms., PMID:40084401
The impaired response of nasal epithelial cells to microplastic stimulation in asthma and COPD., PMID:39905077
The structure of FCGBP is formed as a disulfide-mediated homodimer between its C-terminal domains., PMID:39754272
FCGBP functions as a tumor suppressor gene in head and neck squamous cell carcinoma., PMID:39580769
Deciphering Proteomic Expression in Inflammatory Disorders: A Mass Spectrometry Exploration Comparing Infectious, Noninfectious, and Traumatic Brain Injuries in Human Cerebrospinal Fluid., PMID:39391051
Deciphering glial contributions to CSF1R-related disorder via single-nuclear transcriptomic profiling: a case study., PMID:39217398
Identification of Key Efferocytosis-Related Genes and Mechanisms in Diabetic Retinopathy., PMID:39085562
Proteomic profiling of extracellular vesicles derived from human serum for the discovery of biomarkers in Avascular necrosis., PMID:38825675
Predictive value of FCGBP expression for treatment response and survival in rectal cancer patients undergoing chemoradiotherapy., PMID:38709264
Different Forms of TFF3 in the Human Endocervix, including a Complex with IgG Fc Binding Protein (FCGBP), and Further Aspects of the Cervico-Vaginal Innate Immune Barrier., PMID:38396964
Non-coding RNA-related FCGBP downregulation in head and neck squamous cell carcinoma: a novel biomarker for predicting paclitaxel resistance and immunosuppressive microenvironment., PMID:38396056
VWD domain stabilization by autocatalytic Asp-Pro cleavage., PMID:38380729
Revealing the role of necroptosis microenvironment: FCGBP + tumor-associated macrophages drive primary liver cancer differentiation towards cHCC-CCA or iCCA., PMID:38017206
Integrated Analysis of Transcriptome and Proteome of the Human Cornea and Aqueous Humor Reveal Novel Biomarkers for Corneal Endothelial Cell Dysfunction., PMID:37895034
Whole-Exome Sequencing Identifies Mutation Profile and Mutation Signature-Based Clustering Associated with Prognosis in Appendiceal Pseudomyxoma Peritonei., PMID:37768171
Expression Profiling along the Murine Intestine: Different Mucosal Protection Systems and Alterations in Tff1-Deficient Animals., PMID:37628863
Microbial experience through housing in a farmyard-type environment alters intestinal barrier properties in mouse colons., PMID:37607995
[IgG Fc binding protein (FCGBP) as a prognostic marker of low-grade glioma and its correlation analysis with immune infiltration]., PMID:37515334
IgGFc-binding protein and MUC2 mucin produced by colonic goblet-like cells spatially interact non-covalently and regulate wound healing., PMID:37359538
Colonic mucin-2 attenuates acute necrotizing pancreatitis in rats by modulating intestinal homeostasis., PMID:37249555
IgG Fc-binding protein positively regulates the assembly of pore-forming protein complex βγ-CAT evolved to drive cell vesicular delivery and transport., PMID:37068610
A Novel Prognostic Marker and Therapeutic Target Associated with Glioma Progression in a Tumor Immune Microenvironment., PMID:36883185
Comprehensive LncRNA and Potential Molecular Mechanism Analysis in Noninfectious Uveitis., PMID:36857067
Fc fragment of IgG binding protein is correlated with immune infiltration levels in hepatocellular carcinoma., PMID:36803544
Panomics reveals patient individuality as the major driver of colorectal cancer progression., PMID:36691026
Single-cell profiling reveals differences between human classical adenocarcinoma and mucinous adenocarcinoma., PMID:36690709
Different Molecular Forms of TFF3 in the Human Respiratory Tract: Heterodimerization with IgG Fc Binding Protein (FCGBP) and Proteolytic Cleavage in Bronchial Secretions., PMID:36499686
Whole-Exome Sequencing Among Chinese Patients With Hereditary Diffuse Gastric Cancer., PMID:36484990
Transcriptomic analysis reveals an association of FCGBP with Parkinson's disease., PMID:36371440
Establishment and verification of potential biomarkers for cholangiocarcinoma., PMID:35978916
Role of the mucin-like glycoprotein FCGBP in mucosal immunity and cancer., PMID:35936008
Prognostic and therapeutic prediction by screening signature combinations from transcriptome-methylome interactions in oral squamous cell carcinoma., PMID:35794182
FCGBP Is a Promising Prognostic Biomarker and Correlates with Immunotherapy Efficacy in Oral Squamous Cell Carcinoma., PMID:35733916
Cinobufagin inhibits tumor progression and reduces doxorubicin resistance by enhancing FOXO1-mediated transcription of FCGBP in osteosarcoma., PMID:35690338
Multi-Omics Analyses to Identify FCGBP as a Potential Predictor in Head and Neck Squamous Cell Carcinoma., PMID:35626334
Global N6-methyladenosine methylation analysis reveals the positive correlation between m6A modification and mRNA abundance during Apostichopus japonicus disease development., PMID:35562078
Transcriptional Profiling and Deriving a Seven-Gene Signature That Discriminates Active and Latent Tuberculosis: An Integrative Bioinformatics Approach., PMID:35456421
FcGBP and VCAM-1 are ponderable biomarkers for differential diagnosis of alcoholic liver cirrhosis., PMID:35245761
Definition of an Inflammatory Biomarker Signature in Plasma-Derived Extracellular Vesicles of Glioblastoma Patients., PMID:35052804
FCGBP Is a Prognostic Biomarker and Associated With Immune Infiltration in Glioma., PMID:35047393
Salivary Trefoil Factor Family (TFF) Peptides and Their Roles in Oral and Esophageal Protection: Therapeutic Potential., PMID:34830103
Low expression of TFF3 in papillary thyroid carcinoma may correlate with poor prognosis but high immune cell infiltration., PMID:34756116
Glycoprotein Pathways Altered in Frontotemporal Dementia With Autoimmune Disease., PMID:34539672
Neglected roles of IgG Fc-binding protein secreted from airway mucin-producing cells in protecting against SARS-CoV-2 infection., PMID:34521229
A Transcriptomic Analysis of Head and Neck Squamous Cell Carcinomas for Prognostic Indications., PMID:34442426