Catalog No.
YHJ90701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val201-Asp410
Predicted molecular weight
25.80 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y679
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ancient ubiquitous protein 1, AUP1, Lipid droplet-regulating VLDL assembly factor AUP1
The role of ancient ubiquitous protein 1 (Aup1) in regulating hepatic lipid droplet levels, endoplasmic reticulum stress, and inflammation in zebrafish (Danio rerio)., PMID:40484276
AUP1 and UBE2G2 complex targets STING signaling and regulates virus-induced innate immunity., PMID:40237449
AUP1 transcriptionally activated by KDM5B reprograms lipid metabolism to promote the malignant progression of cervical cancer., PMID:39329209
Increased Immune Infiltration and Improved Prognosis of Head and Neck Squamous Cell Carcinoma Associated with Reduced Ancient Ubiquitous Protein 1 Gene Expression., PMID:38862860
AUP1 Regulates the Endoplasmic Reticulum-Associated Degradation and Polyubiquitination of NKCC2., PMID:38474353
Featured interactome of homocysteine-inducible endoplasmic reticulum protein uncovers novel binding partners in response to ER stress., PMID:37736299
The pyruvate dehydrogenase complex regulates mitophagic trafficking and protein phosphorylation., PMID:37442609
Viral subversion of selective autophagy is critical for biogenesis of virus replication organelles., PMID:37164963
Ancient ubiquitous protein 1 (AUP1) is a prognostic biomarker connected with TP53 mutation and the inflamed microenvironments in glioma., PMID:37029364
The Potential of Lipid Droplet-associated Genes as Diagnostic and Prognostic Biomarkers in Head and Neck Squamous Cell Carcinoma., PMID:36998140
AUP1 regulates lipid metabolism and induces lipid accumulation to accelerate the progression of renal clear cell carcinoma., PMID:35633317
A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation., PMID:34879065
Comparative phosphoproteomic provides insights into meat quality differences between slow- and fast-growing broilers., PMID:34710681
The ménage à trois of autophagy, lipid droplets and liver disease., PMID:33794741
Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells., PMID:33590792
Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation., PMID:31548421
Lipid Droplet Metabolism during Dengue Virus Infection., PMID:29909044
Flaviviruses Exploit the Lipid Droplet Protein AUP1 to Trigger Lipophagy and Drive Virus Production., PMID:29902443
AUP1 (Ancient Ubiquitous Protein 1): A Molecular Link Between Hepatic Lipid Mobilization and VLDL Secretion., PMID:28330944
AUP1 (Ancient Ubiquitous Protein 1) Is a Key Determinant of Hepatic Very-Low-Density Lipoprotein Assembly and Secretion., PMID:28183703
Monoubiquitination of ancient ubiquitous protein 1 promotes lipid droplet clustering., PMID:24039768
Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes., PMID:23223569
Monotopic topology is required for lipid droplet targeting of ancient ubiquitous protein 1., PMID:23197321
Dual role of ancient ubiquitous protein 1 (AUP1) in lipid droplet accumulation and endoplasmic reticulum (ER) protein quality control., PMID:21857022
Ancient ubiquitous protein 1 (AUP1) localizes to lipid droplets and binds the E2 ubiquitin conjugase G2 (Ube2g2) via its G2 binding region., PMID:21127063
The transmembrane segment of a tail-anchored protein determines its degradative fate through dislocation from the endoplasmic reticulum., PMID:20435896
Aup1-mediated regulation of Rtg3 during mitophagy., PMID:19840933
Live cell multicolor imaging of lipid droplets with a new dye, LD540., PMID:19765264
Ancient ubiquitous protein 1 and Syk link cytoplasmic tails of the integrin alpha(IIb)beta(3)., PMID:19235052
SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins., PMID:18711132
A peptide affinity column for the identification of integrin alpha IIb-binding proteins., PMID:18082615
Mitophagy: the life-or-death dichotomy includes yeast., PMID:17329958
[Activation (inside-out signaling) of integrin alphaIIb beta3]., PMID:17313071
[A new human cellular protein AUP1. III. The intracellular localization of AUP1 protein in different human and rat cell lines]., PMID:12534238
[A new human cellular protein AUP1. II. cDNA cloning, genomic organization of Aup1 gene ans preliminary characterization of human AUP1 protein]., PMID:12534237
[A new human cellular protein AUP1. I. In vitro interaction of AUP1 with adenoviral proteins E4ORF3 and E1A]., PMID:12534236
Ancient ubiquitous protein 1 binds to the conserved membrane-proximal sequence of the cytoplasmic tail of the integrin alpha subunits that plays a crucial role in the inside-out signaling of alpha IIbbeta 3., PMID:12042322
DQX1, an RNA-dependent ATPase homolog with a novel DEAQ box: expression pattern and genomic sequence comparison of the human and mouse genes., PMID:11353393
High-resolution genetic, physical, and transcript map of the mnd2 region of mouse chromosome 6., PMID:9806835
Aup1, a novel gene on mouse chromosome 6 and human chromosome 2p13., PMID:8812468
Australia antigen: large-scale purification from human serum and biochemical studies of its proteins., PMID:5105002
For research use only. Not for human or drug use.
