Catalog No.
YHJ90001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala175-Ile412
Predicted molecular weight
28.98 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y5X9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Phospholipase A1, Endothelial lipase, EDL, LIPG, EL, Endothelial cell-derived lipase
Transcriptomics characteristics and differentiation of subcutaneous adipose tissue among Huainan pigs and its hybrid genetic populations., PMID:40475027
Gene-Diet Interactions in High-Density Lipoprotein Cholesterol-Related Polymorphisms and Cardiovascular Disease Risk: Insights from the Korean Genome and Epidemiology Study., PMID:40077648
LIPG-mediated regulation of lipid deposition and proliferation in goat intramuscular preadipocytes involves the PPARα signaling pathway., PMID:39946436
Endothelial lipase-binding peptides similar to netrin-1 inhibit hepatitis B virus infection., PMID:39865491
EPAS1 Attenuates Atherosclerosis Initiation at Disturbed Flow Sites Through Endothelial Fatty Acid Uptake., PMID:39234692
ZDHHC1 downregulates LIPG and inhibits colorectal cancer growth via IGF2BP1 Palmitoylation., PMID:39069526
Blocking H1R signal aggravates atherosclerosis by promoting inflammation and foam cell formation., PMID:38733386
No association of endothelial lipase and aldose reductase polymorphisms with proliferative diabetic retinopathy: Results of the French prospective multicenter REDIAGEN study., PMID:38570135
Endothelial lipase variant T111I does not alter inhibition by angiopoietin-like proteins., PMID:38379026
Cornelian Cherry (Cornus mas L.) Fruit Extract Lowers SREBP-1c and C/EBPα in Liver and Alters Various PPAR-α, PPAR-γ, LXR-α Target Genes in Cholesterol-Rich Diet Rabbit Model., PMID:38256272
Endothelial Lipase Variant, T111I, Does Not Alter Inhibition by Angiopoietin-like Proteins., PMID:37693454
Functional involvement of endothelial lipase in hepatitis B virus infection., PMID:37655967
Integrated analysis of DNA methylome and transcriptome reveals SFRP1 and LIPG as potential drivers of ovarian cancer metastasis., PMID:37417299
Differences in gene regulation by TLR3 and IPS-1 signaling in murine corneal epithelial cells., PMID:37193897
Amphiregulin blockade decreases the levodopa-induced dyskinesia in a 6-hydroxydopamine Parkinson's disease mouse model., PMID:37101388
Mechanistic analysis of endothelial lipase G promotion of the occurrence and development of cervical carcinoma by activating the phosphatidylinositol-4,5-bisphosphate 3-kinase/protein kinase B/mechanistic target of rapamycin kinase signalling pathway., PMID:36606668
Identification of Biomarkers Associated with the Prognoses of Colorectal Cancer Patients., PMID:36577392
LIPG is a novel prognostic biomarker and correlated with immune infiltrates in lung adenocarcinoma., PMID:36572999
Genetic Mimicry Analysis Reveals the Specific Lipases Targeted by the ANGPTL3-ANGPTL8 Complex and ANGPTL4., PMID:36372100
Obesity downregulates lipid metabolism genes in first trimester placenta., PMID:36371454
Multi-omics analysis identifies potential mechanisms by which high glucose accelerates macrophage foaming., PMID:36029453
Plasma HDL pattern, cholesterol efflux and cholesterol loading capacity of serum in carriers of a novel missense variant (Gly176Trp) of endothelial lipase., PMID:36002365
A Proof-of-Concept Inhibitor of Endothelial Lipase Suppresses Triple-Negative Breast Cancer Cells by Hijacking the Mitochondrial Function., PMID:35954428
HIV-1 Tat and cocaine impact astrocytic energy reservoirs and epigenetic regulation by influencing the LINC01133-hsa-miR-4726-5p-NDUFA9 axis., PMID:35892093
Effects of heat-processed Gynostemma pentaphyllum on high-fat diet-fed mice of obesity and functional analysis on network pharmacology and molecular docking strategy., PMID:35513215
LEGACY: Phase 2a Trial to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamic Effects of the Anti-EL (Endothelial Lipase) Antibody MEDI5884 in Patients With Stable Coronary Artery Disease., PMID:34706556
Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins., PMID:34543263
Evaluation of feeding behaviour traits to predict efficiency traits in pigs using partial least square regression., PMID:34534763
Population-Based Impact of Smoking, Drinking, and Genetic Factors on HDL-cholesterol Levels in J-MICC Study Participants., PMID:34421081
A novel strategy to identify candidate diagnostic and prognostic biomarkers for gastric cancer., PMID:34215253
Potential role of hepatic lipase in the accretion of docosahexaenoic acid (DHA) by the brain., PMID:34197964
Molecular mechanisms of fat deposition: IL-6 is a hub gene in fat lipolysis, comparing thin-tailed with fat-tailed sheep breeds., PMID:34084904
LIPG endothelial lipase and breast cancer risk by subtypes., PMID:34001944
Roles of endothelial lipase gene related single nucleotide polymorphisms in patients with coronary artery disease., PMID:33882321
Genome-Wide Analyses Reveal Genetic Convergence of Prolificacy between Goats and Sheep., PMID:33810234
Case-Control Study and Meta-Analysis of the Association Between LIPG rs9958947 SNP and Stroke Risk., PMID:33479916
Atherosclerotic cardiovascular disease in hyperalphalipoproteinemia due to LIPG variants., PMID:33414088
Quantile-Dependent Expressivity and Gene-Lifestyle Interactions Involving High-Density Lipoprotein Cholesterol., PMID:33296900
The Hepatic Microenvironment Uniquely Protects Leukemia Cells through Induction of Growth and Survival Pathways Mediated by LIPG., PMID:33028621
Significant association between the endothelial lipase gene 584C/T polymorphism and coronary artery disease risk., PMID:32893849
Sialylation of Asparagine 612 Inhibits Aconitase Activity during Mouse Sperm Capacitation; a Possible Mechanism for the Switch from Oxidative Phosphorylation to Glycolysis., PMID:32839225
LDL-Cholesterol Reduction by ANGPTL3 Inhibition in Mice Is Dependent on Endothelial Lipase., PMID:32808882
Gene polymorphism associated with angiotensinogen (M235T), endothelial lipase (584C/T) and susceptibility to coronary artery disease: a meta-analysis., PMID:32667032
Angiopoietin-like protein 3 governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance., PMID:32646941
Dysregulation of cancer genes by recurrent intergenic fusions., PMID:32631391
LIPG: an inflammation and cancer modulator., PMID:32572177
Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels., PMID:32510982
Inhibition of LIPG phospholipase activity suppresses tumor formation of human basal-like triple-negative breast cancer., PMID:32488004
Cholesterol Homeostasis Modulates Platinum Sensitivity in Human Ovarian Cancer., PMID:32235572
Identification of Reversible Small Molecule Inhibitors of Endothelial Lipase (EL) That Demonstrate HDL-C Increase In Vivo., PMID:31990537
For research use only. Not for human or drug use.
