Catalog No.
YHJ89401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu331-Gln445
Predicted molecular weight
15.81 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y5Q0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Delta(13) fatty acid desaturase, Delta(13) desaturase, FADS3, Fatty acid desaturase 3, CYB5RP
Exosomal transcript cargo and functional correlation with HNSCC patients' survival., PMID:39272022
Identification of genomic regions, genetic variants and gene networks regulating candidate genes for lipid metabolism in pig muscle., PMID:38064855
The atypical sphingolipid SPB 18:1(14Z);O2 is a biomarker for DEGS1 related hypomyelinating leukodystrophy., PMID:37890668
FADS2 function at the major cancer hotspot 11q13 locus alters fatty acid metabolism in cancer., PMID:37597812
Investigating the role of FADS family members in breast cancer based on bioinformatic analysis and experimental validation., PMID:37122728
Overexpression of fatty acid desaturase 3 predicts poor prognosis in head and neck squamous cell carcinoma., PMID:36626435
Novel Interactions of Myristic Acid and FADS3 Variants Predict Atopic Dermatitis among Indonesian Infants., PMID:36364938
FADS cluster variants are associated with insulin sensitivity in children and adolescents with overweight and obesity., PMID:35906330
Genes regulating levels of ω-3 long-chain polyunsaturated fatty acids are associated with alcohol use disorder and consumption, and broader externalizing behavior in humans., PMID:35904282
PSRC1 May Affect Coronary Artery Disease Risk by Altering CELSR2, PSRC1, and SORT1 Gene Expression and Circulating Granulin and Apolipoprotein B Protein Levels., PMID:35252377
Variation in biomarker levels of metals, persistent organic pollutants, and omega-3 fatty acids in association with genetic polymorphisms among Inuit in Nunavik, Canada., PMID:34062203
FADS genetic and metabolomic analyses identify the ∆5 desaturase (FADS1) step as a critical control point in the formation of biologically important lipids., PMID:32985521
Mutations in sphingolipid metabolism genes are associated with ADHD., PMID:32661301
Genome-Wide Association Study for Serum Omega-3 and Omega-6 Polyunsaturated Fatty Acids: Exploratory Analysis of the Sex-Specific Effects and Dietary Modulation in Mediterranean Subjects with Metabolic Syndrome., PMID:31991592
Biosynthesis of the anti-lipid-microdomain sphingoid base 4,14-sphingadiene by the ceramide desaturase FADS3., PMID:31916624
Hypothalamic proteome changes in response to nicotine and its withdrawal are potentially associated with alteration in body weight., PMID:31911195
FADS3 is a Δ14Z sphingoid base desaturase that contributes to gender differences in the human plasma sphingolipidome., PMID:31862735
Early nutrition in combination with polymorphisms in fatty acid desaturase gene cluster modulate fatty acid composition of cheek cells' glycerophospholipids in school-age children., PMID:31638497
Fatty Acid Desaturase 3 (FADS3) Is a Specific ∆13-Desaturase of Ruminant trans-Vaccenic Acid., PMID:32911476
Effect of diets supplemented with starch and corn oil, marine algae, or hydrogenated palm oil on mammary lipogenic gene expression in cows and goats: A comparative study., PMID:30343921
Conversion of dietary trans-vaccenic acid to trans11,cis13-conjugated linoleic acid in the rat lactating mammary gland by Fatty Acid Desaturase 3-catalyzed methyl-end Δ13-desaturation., PMID:30262139
Long-chain polyunsaturated fatty acids, gestation duration, and birth size: a Mendelian randomization study using fatty acid desaturase variants., PMID:29878044
The combined effects of FADS gene variation and dietary fats in obesity-related traits in a population from the far north of Sweden: the GLACIER Study., PMID:29795460
The distribution of three candidate cold-resistant SNPs in six minorities in North China., PMID:29433421
Fads3 modulates docosahexaenoic acid in liver and brain., PMID:28838557
Study protocol to investigate the environmental and genetic aetiology of atopic dermatitis: the Indonesian Prospective Study of Atopic Dermatitis in Infants (ISADI)., PMID:28259851
Association of the FADS gene cluster with coronary artery disease and plasma lipid concentrations in the northern Chinese Han population., PMID:28237083
Genetic polymorphisms of FADS1, FADS2, and FADS3 and fatty acid profiles in subjects received methadone maintenance therapy., PMID:28161285
Genetic Variants of the FADS Gene Cluster Are Associated with Erythrocyte Membrane LC PUFA Levels in Patients with Mild Cognitive Impairment., PMID:27273350
Association of polyunsaturated fatty acids in breast milk with fatty acid desaturase gene polymorphisms among Chinese lactating mothers., PMID:27269715
Alternative splicing generates novel Fads3 transcript in mice., PMID:27216536
Genomic structural analysis of porcine fatty acid desaturase cluster on chromosome 2., PMID:25409917
Fatty acid desaturase 1 gene polymorphisms control human hepatic lipid composition., PMID:25123259
Genetic variants in desaturase gene, erythrocyte fatty acids, and risk for type 2 diabetes in Chinese Hans., PMID:24985009
Control of adipose tissue expandability in response to high fat diet by the insulin-like growth factor-binding protein-4., PMID:24778188
Unsaturated fatty acids, desaturases, and human health., PMID:24460221
Dietary arachidonic acid and docosahexaenoic acid regulate liver fatty acid desaturase (FADS) alternative transcript expression in suckling piglets., PMID:24075244
Trans-vaccenate is Δ13-desaturated by FADS3 in rodents., PMID:24070791
The 51 kDa FADS3 is secreted in the ECM of hepatocytes and blood in rat., PMID:23966218
Association of polymorphisms in FADS gene with age-related changes in serum phospholipid polyunsaturated fatty acids and oxidative stress markers in middle-aged nonobese men., PMID:23818766
FADS genotype and diet are important determinants of DHA status: a cross-sectional study in Danish infants., PMID:23636240
Umbilical cord PUFA are determined by maternal and child fatty acid desaturase (FADS) genetic variants in the Avon Longitudinal Study of Parents and Children (ALSPAC)., PMID:22877655
Dietary long-chain polyunsaturated fatty acids upregulate expression of FADS3 transcripts., PMID:22398025
The polypyrimidine tract binding protein regulates desaturase alternative splicing and PUFA composition., PMID:21980057
Genetic variation in polyunsaturated fatty acid metabolism and its potential relevance for human development and health., PMID:21366865
Genetic variants of the fatty acid desaturase gene cluster predict amounts of red blood cell docosahexaenoic and other polyunsaturated fatty acids in pregnant women: findings from the Avon Longitudinal Study of Parents and Children., PMID:21106917
FADS gene polymorphisms in Koreans: association with ω6 polyunsaturated fatty acids in serum phospholipids, lipid peroxides, and coronary artery disease., PMID:21040914
Separating the contribution of glucocorticoids and wakefulness to the molecular and electrophysiological correlates of sleep homeostasis., PMID:20857860
Alternative transcripts of fatty acid desaturase (FADS) genes., PMID:20236814
Fatty Acid Desaturase 3 (Fads3) is a singular member of the Fads cluster., PMID:20226833
For research use only. Not for human or drug use.
