Catalog No.
YHJ89301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr149-Glu429
Predicted molecular weight
33.03 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y5K6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD2-associated protein, Adapter protein CMS, Cas ligand with multiple SH3 domains, CD2AP
CD2AP at the junction of nephropathy and Alzheimer's disease., PMID:40462155
CD2AP shapes a stromal reduced tumor microenvironment and contributes to immunotherapy in gastric cancer., PMID:40399857
Integrated Analysis of Disulfidptosis-Related Genes Identifies CD2AP as a Potential Therapeutic Target for Hepatocellular Carcinoma., PMID:40362690
Integrated bioinformatic analysis of immune infiltration and disulfidptosis related gene subgroups in type A aortic dissection., PMID:40258895
Effects of steroid-resistant nephrotic syndrome serum on AA pathway in podocytes cultured in 3D in vitro glomerular model., PMID:40229314
Computational and functional prioritization identifies genes that rescue behavior and reduce tau protein in fly and human cell models of Alzheimer disease., PMID:40215969
Identification of the disulfidptosis-related key gene CD2AP as a potential biomarker and new therapeutic target for LUAD patients by comprehensive multi-omics analysis., PMID:40214854
Inhibition of LINC00707/miR-223-3p/FKBP5 axis has a protective effect on diabetic kidney disease., PMID:40114624
Sexual dimorphism in cerebrovascular dysfunction: The pivotal role of endothelial CD2AP in Alzheimer's disease., PMID:40112772
Biomarker identification for Alzheimer's disease through integration of comprehensive Mendelian randomization and proteomics data., PMID:40050982
Loss of endothelial CD2AP causes sex-dependent cerebrovascular dysfunction., PMID:39892386
APP lysine 612 lactylation ameliorates amyloid pathology and memory decline in Alzheimer's disease., PMID:39744941
Shensu IV maintains the integrity of the glomerular filtration barrier and exerts renal protective effects by regulating endogenous hydrogen sulfide levels., PMID:39720588
CD2AP deficiency aggravates Alzheimer's disease phenotypes and pathology through p38 MAPK activation., PMID:39696695
Microglial CD2AP deficiency exerts protection in an Alzheimer's disease model of amyloidosis., PMID:39695808
Identification of Alzheimer's disease susceptibility genes by integrating eight human brain single-cell transcriptomes with genome-wide association studies., PMID:39655660
Consistent genes associated with structural changes in clinical Alzheimer's disease spectrum., PMID:39554844
Reconstitution of Arp2/3-nucleated actin assembly with proteins CP, V-1, and CARMIL., PMID:39437783
The Alzheimer's Disease Risk Gene CD2AP Functions in Dendritic Spines by Remodeling F-Actin., PMID:39406515
CD2AP promotes the progression of glioblastoma multiforme via TRIM5-mediated NF-kB signaling., PMID:39353894
Predictive value analysis of the interaction network of Tks4 scaffold protein in colon cancer., PMID:39234565
CD2AP is Co-Expressed with Tropomyosin-Related Kinase A and Ras-Related Protein Rab-5A in Cholinergic Neurons of the Murine Basal Forebrain., PMID:39211110
Renal Protective Effect of Boeravinone B against Diabetic Nephropathy Rats via Inhibition of The Inflammatory and JAK2/STAT3 Signalling Pathway., PMID:39154235
Alzheimer's disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity., PMID:39146503
The Role of Changes in the Expression of Inflammation-Associated Genes in the Variants of Cerebral Small Vessel Disease., PMID:39125683
The Immunosuppressive Drug LF15-0195 Acts Also on Glomerular Lesions, by a Change in Cytoskeleton Distribution in Podocyte., PMID:39074452
Acupuncture improve proteinuria in diabetic kidney disease rats by inhibiting ferroptosis and epithelial-mesenchymal transition., PMID:39071725
Unraveling pathogenesis, biomarkers and potential therapeutic agents for endometriosis associated with disulfidptosis based on bioinformatics analysis, machine learning and experiment validation., PMID:39061076
Human cytomegalovirus pUL135 protein affects endothelial cell function via CD2AP in Kawasaki disease., PMID:39025135
Comprehensive analysis of disulfidptosis-related genes reveals the effect of disulfidptosis in ulcerative colitis., PMID:38977802
Reconstitution of Arp2/3-Nucleated Actin Assembly with CP, V-1 and CARMIL., PMID:38798690
Comprehensive Urinary Proteome Profiling Analysis Identifies Diagnosis and Relapse Surveillance Biomarkers for Bladder Cancer., PMID:38787199
Hypoxia-inducible factor-1α attenuates renal podocyte injury in male rats in a simulated high-altitude environment by upregulating Krüppel-like factor 4 expression., PMID:38774964
Biophysical characterization and insights into the oligomeric nature of CD2-associated protein., PMID:38765876
TurboID mapping reveals the exportome of secreted intrinsically disordered proteins in the transforming parasite Theileria annulata., PMID:38747635
Indoxyl Sulfate Aggravates Podocyte Damage through the TGF-β1/Smad/ROS Signalling Pathway., PMID:38735279
Disulfidptosis-related signature elucidates the prognostic, immunologic, and therapeutic characteristics in ovarian cancer., PMID:38694875
CD2AP is a potential prognostic biomarker of renal clear cell carcinoma., PMID:38457255
Noncanonical function of folate through folate receptor 1 during neural tube formation., PMID:38388461
Hepatitis B virus-targeting sodium taurocholate cotransporting polypeptide mediates HBV infection and damage in human renal podocytes., PMID:38315030
Knowledge domains and emerging trends of Genome-wide association studies in Alzheimer's disease: A bibliometric analysis and visualization study from 2002 to 2022., PMID:38241287
Collapsing Glomerulopathy in a Patient with a TRPC6 Mutation Presenting as Rapidly Progressive Glomerulonephritis: A Case Report and Review of the Literature., PMID:38231721
Studying the Association of TKS4 and CD2AP Scaffold Proteins and Their Implications in the Partial Epithelial-Mesenchymal Transition (EMT) Process., PMID:37894817
Pan-cancer genetic analysis of disulfidptosis-related gene set., PMID:37879141
[Effects and mechanisms of total flavones of Abelmoschus manihot in inhibiting podocyte necroptosis and renal fibrosis in diabetic kidney disease]., PMID:37802782
Angiopoietin-like protein 3 deficiency combined with valsartan administration protects better against podocyte damage in streptozotocin-induced diabetic nephropathy mice., PMID:37724955
Minnelide combined with anti-ANGPTL3-FLD monoclonal antibody completely protects mice with adriamycin nephropathy by promoting autophagy and inhibiting apoptosis., PMID:37689694
Ocular manifestations of the genetic causes of focal and segmental glomerulosclerosis., PMID:37578539
Non-canonical function of folate/folate receptor 1 during neural tube formation., PMID:37503108
RhoGAP6 interacts with COPI to regulate protein transport., PMID:37409526
For research use only. Not for human or drug use.
