Catalog No.
YHJ88201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro1502-Met1719
Predicted molecular weight
27.20 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y4K1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Beta/gamma crystallin domain-containing protein 1, Absent in melanoma 1 protein, CRYBG1, AIM1
Multiomics profiles of genome-wide alterations in H3K27ac in different lung lobes after acute graft-versus-host disease with MSCs treatment., PMID:40443676
Molecular Characterization and Subtyping of Breast Cancer Cell Lines Provide Novel Insights into Cancer Relevant Genes., PMID:38391914
Establishment of ganglioside GD2-expressing extranodal NK/T-cell lymphoma cell line with scRNA-seq analysis., PMID:38029851
Purification and Functional Characterization of the C-Terminal Domain of the β-Actin-Binding Protein AIM1 In Vitro., PMID:30544954
AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination., PMID:28747635
DNMT1 and AIM1 Imprinting in human placenta revealed through a genome-wide screen for allele-specific DNA methylation., PMID:24094292
Novel role of PKR in inflammasome activation and HMGB1 release., PMID:22801494
High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer., PMID:22761906
Molecular features of hepatosplenic T-cell lymphoma unravels potential novel therapeutic targets., PMID:22510872
AIM1 and LINE-1 epigenetic aberrations in tumor and serum relate to melanoma progression and disease outcome., PMID:22402438
AIM1 promoter hypermethylation as a predictor of decreased risk of recurrence following radical prostatectomy., PMID:22127895
Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies., PMID:19194464
Exploring the limits of sequence and structure in a variant betagamma-crystallin domain of the protein absent in melanoma-1 (AIM1)., PMID:18582473
Oculocutaneous albinism type 4: six novel mutations in the membrane-associated transporter protein gene and their phenotypes., PMID:16965274
Identifying the genes causing human diversity., PMID:16723996
Crystallization and preliminary X-ray crystallographic investigations on a betagamma-crystallin domain of absent in melanoma 1 (AIM1), a protein from Homo sapiens., PMID:16511323
Evidence for recent positive selection at the human AIM1 locus in a European population., PMID:16162863
Meningococccal meningitis and complement component 6 deficiency associated with oculocutaneous albinism., PMID:15565285
High expression of Aurora-B/Aurora and Ipll-like midbody-associated protein (AIM-1) in astrocytomas., PMID:15072448
Homology modeling provides insights into the binding mode of the PAAD/DAPIN/pyrin domain, a fourth member of the CARD/DD/DED domain family., PMID:12930987
Stability, homodimerization, and calcium-binding properties of a single, variant betagamma-crystallin domain of the protein absent in melanoma 1 (AIM1)., PMID:12693952
Distinctive distribution of AIM1 polymorphism among major human populations with different skin color., PMID:11916009
Identification of Aim-1 as the underwhite mouse mutant and its transcriptional regulation by MITF., PMID:11700328
Mutations in the gene encoding B, a novel transporter protein, reduce melanin content in medaka., PMID:11479596
Use of an in vitro immunoselected tumor line to identify shared melanoma antigens recognized by HLA-A*0201-restricted T cells., PMID:11221837
Cloning and tissue expression of the mouse ortholog of AIM1, a betagamma-crystallin superfamily member., PMID:9716656
AIM1, a novel non-lens member of the betagamma-crystallin superfamily, is associated with the control of tumorigenicity in human malignant melanoma., PMID:9096375
For research use only. Not for human or drug use.
