Catalog No.
YHJ88101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser1531-Val1855
Predicted molecular weight
39.36 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y4I1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MYH12, Myosin heavy chain 12, Dilute myosin heavy chain, non-muscle, Unconventional myosin-Va, Myoxin, MYO5A, Myosin-12
SRSF10 regulates oligodendrocyte differentiation during mouse central nervous system development by modulating pre-mRNA splicing., PMID:40439883
Phosphorylated septin 3 delocalizes from the spine base and facilitates endoplasmic reticulum extension into spines via myosin-Va., PMID:40375097
A novel, rapidly progressive ataxia due to a spontaneous Myo5a mutation in mice impairs transport proteins and alters mitochondria., PMID:40022605
Molecular Markers of Occult Lymph Node Metastasis in Head and Neck Squamous Cell Carcinoma (HNSCC) Patients., PMID:40018925
Clinical, Morphologic, and Genomic Findings in Spitz Tumors With RET Fusion: A Series of 31 Cases., PMID:39986469
Cardiac dysfunction related to cardiac mRNA and protein traffic impairment due to reduced unconventional motor protein myosin-5b expression., PMID:39969162
Determination of Dissociation Constants for the Interaction of Myosin-5a with its Cargo Protein Using Microscale Thermophoresis (MST)., PMID:39959298
Mechanistic insights into retinoic-acid treatment for autism in the improvement of social behavior: Evidence from a multi omics study in rats., PMID:39643238
Exploiting cryo-EM structures of actomyosin-5a to reveal the physical properties of its lever., PMID:39454567
Myosin-5a facilitates stress granule formation by interacting with G3BP1., PMID:39387926
Rab27a GTPase and its effector Myosin Va are host factors required for efficient Oropouche virus cell egress., PMID:39213446
Spitz Melanoma With SLC20A1::ALK Fusion: A Novel Fusion Previously Undescribed in Spitz Melanocytic Neoplasm., PMID:38941542
Identification of a third myosin-5a-melanophilin interaction that mediates the association of myosin-5a with melanosomes., PMID:38900147
BMP-2 regulates the expression of myosin Va via smad in melan-a melanocyte., PMID:38787453
Early Chronic Fluoxetine Treatment of Ts65Dn Mice Rescues Synaptic Vesicular Deficits and Prevents Aberrant Proteomic Alterations., PMID:38674386
BAG5 regulates HSPA8-mediated protein folding required for sperm head-tail coupling apparatus assembly., PMID:38454159
Spitz melanocytic neoplasms with MLPH::ALK fusions: Report of two cases with previously unreported features and literature review., PMID:38444194
Myosin Va-dependent Transport of NMDA Receptors in Hippocampal Neurons., PMID:38291290
Differential Myosin 5a splice variants in innervation of pelvic organs., PMID:38148903
MYO5A overexpression promotes invasion and correlates with low lymphocyte infiltration in head and neck squamous carcinoma., PMID:38129784
Novel gene fusion discovery in Spitz tumours and its relevance in diagnostics., PMID:37731064
circFNDC3B promotes esophageal squamous cell carcinoma progression by targeting MYO5A via miR-370-3p/miR-136-5p., PMID:37667251
Idiopathic Pulmonary Arterial Hypertension: Network-Based Integration of Multi-Omics Data Reveals New Molecular Signatures and Candidate Drugs., PMID:37410515
Myosin Va, a Novel Interaction Partner of STXBP1, Is Required to Transport Syntaxin1A to the Plasma Membrane., PMID:37315734
Circ-FNDC3B Functions as an Oncogenic Factor in Esophageal Squamous Cell Carcinoma via Upregulating MYO5A by Absorbing miR-136-5p and miR-370-3p., PMID:36884165
Griscelli syndrome type 1: a novel pathogenic variant, and review of literature., PMID:36651988
Genome-Wide Association and Inheritance-Based Analyses Implicate Unconventional Myosin Genes in Hypoplastic Left Heart Syndrome., PMID:36580305
Genomic and transcriptomic profiling reveals key molecules in metastatic potentials and organ-tropisms of hepatocellular carcinoma., PMID:36539000
Identification of differentially expressed genes in mouse paraspinal muscle in response to microgravity., PMID:36313746
Genome-wide analysis identified candidate variants and genes associated with heat stress adaptation in Egyptian sheep breeds., PMID:36263427
Neonatal Onset of Hemophagocytic Lymphohistiocytosis Due to Prenatal Varicella-Zoster Infection in a Neonate with Griscelli Syndrome Type 2., PMID:36243938
Genome-wide detection of copy number variation in American mink using whole-genome sequencing., PMID:36096727
Comprehensive Analysis of SLC17A9 and Its Prognostic Value in Hepatocellular Carcinoma., PMID:35957868
Loss of CHGA Protein as a Potential Biomarker for Colon Cancer Diagnosis: A Study on Biomarker Discovery by Machine Learning and Confirmation by Immunohistochemistry in Colorectal Cancer Tissue Microarrays., PMID:35681650
Evidence for origin of lavender foal syndrome among Egyptian Arabian horses in Egypt., PMID:35665534
Identification of a Novel MLPH Missense Mutation in a Chinese Griscelli Syndrome 3 Patient., PMID:35602484
Fatal melanoma with a novel MYO5A-BRAF fusion and small associated conventional nevus: A case report and review of literature., PMID:35596628
NGS-based targeted sequencing identified two novel variants in Southwestern Chinese families with oculocutaneous albinism., PMID:35488210
Comprehensive Landscape of Prognostic Significance and Immune Characteristics of Myosins in Squamous Cell Carcinoma of the Head and Neck., PMID:35478939
CREB1K292 and HINFPK330 as Putative Common Therapeutic Targets in Alzheimer's and Parkinson's Disease., PMID:34984308
Rhamnazin suppresses melanosome transport by promoting the ubiquitin-mediated proteasomal degradation of melanophilin., PMID:34955374
Modeling myosin Va liposome transport through actin filament networks reveals a percolation threshold that modulates transport properties., PMID:34935414
Excavating novel diagnostic and prognostic long non-coding RNAs (lncRNAs) for head and neck squamous cell carcinoma: an integrated bioinformatics analysis of competing endogenous RNAs (ceRNAs) and gene co-expression networks., PMID:34898376
MYO5A Frameshift Variant in a Miniature Dachshund with Coat Color Dilution and Neurological Defects Resembling Human Griscelli Syndrome Type 1., PMID:34680875
Integrating Transcriptome-Wide Association Study and mRNA Expression Profiling Identifies Novel Genes Associated With Osteonecrosis of the Femoral Head., PMID:34163523
LncRNA PART1 Promotes Proliferation and Migration, Is Associated with Cancer Stem Cells, and Alters the miRNA Landscape in Triple-Negative Breast Cancer., PMID:34072264
Refractory Seizure in a Patient With Griscelli Syndrome: A Unique Case With One Mutation and a Novel Deletion., PMID:33981514
Expression of Myosin 5a splice variants in murine stomach., PMID:33939222
LRRK2-phosphorylated Rab10 sequesters Myosin Va with RILPL2 during ciliogenesis blockade., PMID:33727250
Novel mutations in the Myo5a gene cause a dilute coat color phenotype in mice., PMID:33715225
For research use only. Not for human or drug use.
