Catalog No.
YHJ87601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg13-Leu242
Predicted molecular weight
52.74 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y478
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
AMPK subunit beta-1, AMPKb, 5'-AMP-activated protein kinase subunit beta-1, AMPK, PRKAB1
Novel therapeutic targets for metabolism-related diseases: proteomic Mendelian randomization and colocalization analyses., PMID:40453312
Identification of ageing-associated gene signatures in heart failure with preserved ejection fraction by integrated bioinformatics analysis and machine learning., PMID:40330147
Identifying therapeutic target genes for diabetic retinopathy using systematic druggable genome-wide Mendelian randomization., PMID:40301928
DNA methylation of genes that mediate autophagosome formation contributes to iodine-induced autoimmune thyroiditis: A population-based study conducted at regions with different iodine levels in China., PMID:39965511
Buddleoside alleviates nonalcoholic steatohepatitis by targeting the AMPK-TFEB signaling pathway., PMID:39936600
Drug risks associated with sarcopenia: a real-world and GWAS study., PMID:39511635
Schisanhenol ameliorates non-alcoholic fatty liver disease via inhibiting miR-802 activation of AMPK-mediated modulation of hepatic lipid metabolism., PMID:39309511
Variances in the Expression Profile of Circadian Clock-Related Genes in Astrocytic Brain Tumors., PMID:39001398
Genetic association of glycemic traits and antihyperglycemic agent target genes with the risk of lung cancer: A Mendelian randomization study., PMID:38850595
[Extracellular Matrix Stiffness Induces Mitochondrial Morphological Heterogeneity via AMPK Activation]., PMID:38322520
Phosphorylation of INF2 by AMPK promotes mitochondrial fission and oncogenic function in endometrial cancer., PMID:38233384
Comparative Efficacy of Metformin and Glimepiride in Modulating Pharmacological Network to Increase BDNF Levels and Benefit Type 2 Diabetes-Related Cognitive Impairment., PMID:38001940
Investigation of enzalutamide, docetaxel, and cabazitaxel resistance in the castration resistant prostate cancer cell line C4 using genome-wide CRISPR/Cas9 screening., PMID:37270558
AMPK is a mechano-metabolic sensor linking cell adhesion and mitochondrial dynamics to Myosin-dependent cell migration., PMID:37217519
Network pharmacology- and molecular docking-based investigation of the therapeutic potential and mechanism of daucosterol against multiple myeloma., PMID:37180669
Metabolic Adaptations and Substrate Oxidation are Unaffected by Exogenous Testosterone Administration during Energy Deficit in Men., PMID:36563086
Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes., PMID:36456625
Network pharmacology and molecular docking approaches to elucidate the potential compounds and targets of Saeng-Ji-Hwang-Ko for treatment of type 2 diabetes mellitus., PMID:36049411
Carbohydrate intake in recovery from aerobic exercise differentiates skeletal muscle microRNA expression., PMID:36044708
Effect of arginine supplementation on the production of milk fat in dairy cows., PMID:35965125
AMP-activated protein kinase β1 or β2 deletion enhances colon cancer cell growth and tumorigenesis., PMID:35880569
Salsalate reduces atherosclerosis through AMPKβ1 in mice., PMID:34425254
Artificial intelligence guided discovery of a barrier-protective therapy in inflammatory bowel disease., PMID:34253728
Selenium triggers Nrf2-AMPK crosstalk to alleviate cadmium-induced autophagy in rabbit cerebrum., PMID:34252479
SNP discovery of PRKAB1 gene and their associations with growth traits in goats., PMID:34106801
Proteome Analysis of USP7 Substrates Revealed Its Role in Melanoma Through PI3K/Akt/FOXO and AMPK Pathways., PMID:33869052
Muscle Transcriptome Analysis Reveals Molecular Pathways Related to Oxidative Phosphorylation, Antioxidant Defense, Fatness and Growth in Mangalitsa and Moravka Pigs., PMID:33809803
WW domain-binding protein 2 overexpression prevents diet-induced liver steatosis and insulin resistance through AMPKβ1., PMID:33658485
A-769662 inhibits adipocyte glucose uptake in an AMPK-independent manner., PMID:33493298
AMPKβ1 and AMPKβ2 define an isoform-specific gene signature in human pluripotent stem cells, differentially mediating cardiac lineage specification., PMID:33454005
Therapeutic inhibition of miR-802 protects against obesity through AMPK-mediated regulation of hepatic lipid metabolism., PMID:33391522
[Partial isoform-specific expression and function of AMPK in ovarian carcinoma]., PMID:32727648
Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms., PMID:32719536
Hematoma Resolution In Vivo Is Directed by Activating Transcription Factor 1., PMID:32611235
Metformin ameliorates animal models of dermatitis., PMID:32347398
AMPK β1 activation suppresses antipsychotic-induced hyperglycemia in mice., PMID:31581839
AMP-activated protein kinase complexes containing the β2 regulatory subunit are up-regulated during and contribute to adipogenesis., PMID:31189568
CAMKK2 Promotes Prostate Cancer Independently of AMPK via Increased Lipogenesis., PMID:30242113
Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly., PMID:30232152
Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK)., PMID:30036059
AMP kinase promotes glioblastoma bioenergetics and tumour growth., PMID:29915361
Inhibitory effect of PXR on ammonia-induced hepatocyte autophagy via P53., PMID:29908302
Visualizing AMPK Drug Binding Sites Through Crystallization of Full-Length Phosphorylated α2β1γ1 Heterotrimer., PMID:29480466
Production and Crystallization of Full-Length Human AMP-Activated Protein Kinase (α1β1γ1)., PMID:29480465
Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK., PMID:28613987
Renoprotective Effects of Metformin are Independent of Organic Cation Transporters 1 &2 and AMP-activated Protein Kinase in the Kidney., PMID:27782167
The AMP-activated protein kinase beta 1 subunit modulates erythrocyte integrity., PMID:27666489
An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice., PMID:27571348
Association of AMPK subunit gene polymorphisms with growth, feed intake, and feed efficiency in meat-type chickens., PMID:27143764
Discovery, synthesis, and structure-activity relationships of 20S-dammar-24-en-2α,3β,12β,20-tetrol (GP) derivatives as a new class of AMPKα2β1γ1 activators., PMID:27132866
For research use only. Not for human or drug use.
