Catalog No.
YHJ87201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asn154
Predicted molecular weight
19.75 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y3C5
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RING finger protein 11, RNF11
Note
For research use only.
Multiple modification and protein interaction signals drive the Ring finger protein 11 (RNF11) E3 ligase to the endosomal compartment., PMID:20676133
Inflammation-induced airway smooth muscle responsiveness is strain dependent in mice., PMID:21255673
The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1., PMID:21765415
IKKα takes control of canonical NF-κB activation., PMID:21852778
WWP1: a versatile ubiquitin E3 ligase in signaling and diseases., PMID:22051607
A splice site variant in the bovine RNF11 gene compromises growth and regulation of the inflammatory response., PMID:22438830
Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling., PMID:22507528
Rnf11-like is a novel component of NF-κB signaling, governing the posterior patterning in the zebrafish embryos., PMID:22609198
Comparative distribution of protein components of the A20 ubiquitin-editing complex in normal human brain., PMID:22634524
A miR-19 regulon that controls NF-κB signaling., PMID:22684508
RNF11 modulates microglia activation through NF-κB signalling cascade., PMID:22975135
Expression of the nuclear factor-κB inhibitor A20 is altered in the cystic fibrosis epithelium., PMID:23018911
[Study on gene differential expressions of substance and energy metabolism in chronic superficial gastritis patients of Pi deficiency syndrome and of pi-wei hygropyrexia syndrome]., PMID:23185754
SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking., PMID:23222715
Focal DNA copy number changes in neuroblastoma target MYCN regulated genes., PMID:23308108
RING finger protein 11 targets TBK1/IKKi kinases to inhibit antiviral signaling., PMID:23308279
RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells., PMID:23318928
Promotion of Hendra virus replication by microRNA 146a., PMID:23345523
Learning contextual gene set interaction networks of cancer with condition specificity., PMID:23418942
NF-κB activity is inversely correlated to RNF11 expression in Parkinson's disease., PMID:23669642
Protein microarray characterization of the S-nitrosoproteome., PMID:24105792
Genetic myostatin decrease in the golden retriever muscular dystrophy model does not significantly affect the ubiquitin proteasome system despite enhancing the severity of disease., PMID:24349620
SARA and RNF11 at the crossroads of EGFR signaling and trafficking., PMID:24377927
RNF11 is a GGA protein cargo and acts as a molecular adaptor for GGA3 ubiquitination mediated by Itch., PMID:25195858
RING finger proteins are involved in the progression of barrett esophagus to esophageal adenocarcinoma: a preliminary study., PMID:25228972
Elucidating dynamic protein-protein interactions and ubiquitination in NF-κB signaling pathways., PMID:25736755
Identification of a novel role of RING finger protein 11 promoting the metastasis of murine melanoma cells., PMID:26550462
MicroRNA-19b-3p Modulates Japanese Encephalitis Virus-Mediated Inflammation via Targeting RNF11., PMID:26937036
Involvement of Ubiquitin-Editing Protein A20 in Modulating Inflammation in Rat Cochlea Associated with Silver Nanoparticle-Induced CD68 Upregulation and TLR4 Activation., PMID:27142878
Identification of dually acylated proteins from complementary DNA resources by cell-free and cellular metabolic labeling., PMID:27480498
Ring Finger Protein 11 Inhibits Melanocortin 3 and 4 Receptor Signaling., PMID:27551276
The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR., PMID:27872256
Hepatic IFNL4 expression is associated with non-response to interferon-based therapy through the regulation of basal interferon-stimulated gene expression in chronic hepatitis C patients., PMID:28036111
RNF11 sequestration of the E3 ligase SMURF2 on membranes antagonizes SMAD7 down-regulation of transforming growth factor β signaling., PMID:28292929
Altered expression of Tumor Necrosis Factor Alpha -Induced Protein 3 correlates with disease severity in Ulcerative Colitis., PMID:28842689
miR-200a-5p regulates myocardial necroptosis induced by Se deficiency via targeting RNF11., PMID:29248830
The RING domain of RING Finger 11 (RNF11) protein binds Ubc13 and inhibits formation of polyubiquitin chains., PMID:29537486
ERK1/2-Dependent Gene Expression Contributing to TGFβ-Induced Lens EMT., PMID:29652528
Gga-miR-19b-3p Inhibits Newcastle Disease Virus Replication by Suppressing Inflammatory Response via Targeting RNF11 and ZMYND11., PMID:31507581
Ring Finger Protein 11 acts on ligand-activated EGFR via the direct interaction with the UIM region of ANKRD13 protein family., PMID:31985874
Comprehensive pharmacogenomic characterization of gastric cancer., PMID:32070411
miR-425-5p Acts as a Molecular Marker and Promoted Proliferation, Migration by Targeting RNF11 in Hepatocellular Carcinoma., PMID:33123581
Ring Finger Protein 11 (RNF11) Modulates Dopamine Release in Drosophila., PMID:33176188
RNF11 at the Crossroads of Protein Ubiquitination., PMID:33187263
Pathogenicity and virulence of Japanese encephalitis virus: Neuroinflammation and neuronal cell damage., PMID:33724154
Endurance exercise training-responsive miR-19b-3p improves skeletal muscle glucose metabolism., PMID:34642330
[Mechanism of ring finger protein 11 regulating Akt signaling pathway to promote osteogenic differentiation of bone marrow mesenchymal stem cells]., PMID:35038807
AKAP12 and RNF11 as Diagnostic Markers of Fibromyalgia and Their Correlation with Immune Infiltration., PMID:36238643
Cisplatin reacts with the RING finger domain of RNF11 and interferes with the protein functions., PMID:36906278
Melanoma With RNF11::BRAF Fusion: A Novel Fusion Previously Undescribed in Melanoma., PMID:40036483
For research use only. Not for human or drug use.
