Catalog No.
YHJ85901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn29-Val310
Predicted molecular weight
35.22 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y2C3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
B3GALT5, Beta-1,3-GalTase 5, UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5, Beta3GalT5, b3Gal-T5, Beta-3-Gx-T5, Beta-1,3-galactosyltransferase 5, UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5, Beta3Gal-T5
DCMS analysis revealed differential selection signatures in the transboundary Sahiwal cattle for major economic traits., PMID:40325078
Structure-Based Mechanism and Specificity of Human Galactosyltransferase β3GalT5., PMID:40130308
Expression of Human β3GalT5-1 in Insect Cells as Active Glycoforms for the Efficient Synthesis of Cancer-Associated Globo-Series Glycans., PMID:40130300
Fucosylation of glycoproteins and glycolipids: opposing roles in cholera intoxication., PMID:39414978
Highly expressed B3GALT5-AS1 contributes to gastric cancer progression by recruiting WDR5 to mediate B3GALT5 and regulating β-catenin/ZEB1 axis., PMID:39224045
Unravelling the Genetic Architecture of Serum Biochemical Indicators in Sheep., PMID:39202351
High expression of B3GALT5 suppresses the galectin-4-mediated peritoneal dissemination of poorly differentiated gastric cancer cells., PMID:39163480
B3galt5 functions as a PXR target gene and regulates obesity and insulin resistance by maintaining intestinal integrity., PMID:39004626
IL-22 promotes mucin-type O-glycosylation and MATH1+ cell-mediated amelioration of intestinal inflammation., PMID:38733584
Long Non-Coding RNA B3GALT5-AS1 Suppresses Keloid Progression by Regulating the β-Trcp1-Mediated Ubiquitination of HuR., PMID:38707608
Competing Endogenous RNAs Crosstalk in Hippocampus: A Potential Mechanism for Neuronal Developing Defects in Down Syndrome., PMID:38536538
Identification of hub genes and biological mechanisms underlying the pathogenesis of asthenozoospermia and chronic epididymitis., PMID:37152990
Overexpression screen of chromosome 21 genes reveals modulators of Sonic hedgehog signaling relevant to Down syndrome., PMID:36995257
Comparison of the Cost and Effect of Combined Conditioned Medium and Conventional Medium for Fallopian Tube Organoid Cultures., PMID:36919683
Weighted gene co-expression network analysis combined with machine learning validation to identify key hub biomarkers in colorectal cancer., PMID:36576616
B3galt5 deficiency attenuates hepatocellular carcinoma by suppressing mTOR/p70s6k-mediated glycolysis., PMID:36495345
Homogeneous antibody and CAR-T cells with improved effector functions targeting SSEA-4 glycan on pancreatic cancer., PMID:34876527
Globo H Is a Promising Theranostic Marker for Intrahepatic Cholangiocarcinoma., PMID:34558839
Long non-coding RNA B3GALT5-AS1 contributes to the progression of gastric cancer via interacting with CSNK2A1., PMID:34306196
High B3GALT5 expression confers poor clinical outcome and contributes to tumor progression and metastasis in breast cancer., PMID:33413566
B3GALT5 knockout alters gycosphingolipid profile and facilitates transition to human naïve pluripotency., PMID:33087559
Serum level of long noncoding RNA B3GALT5-AS1 as a diagnostic biomarker of colorectal cancer., PMID:32207329
SSEA3 and Sialyl Lewis a Glycan Expression Is Controlled by B3GALT5 LTR through Lamin A-NFYA and SIRT1-STAT3 Signaling in Human ES Cells., PMID:31936807
Abnormally expressed long noncoding RNA B3GALT5-AS1 may serve as a biomarker for the diagnostic and prognostic of gastric cancer., PMID:31338903
The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice., PMID:31221853
The pivotal role and mechanism of long non-coding RNA B3GALT5-AS1 in the diagnosis of acute pancreatitis., PMID:31177837
Screening key lncRNAs for human rectal adenocarcinoma based on lncRNA-mRNA functional synergistic network., PMID:31116002
Signaling pathway of globo-series glycosphingolipids and β1,3-galactosyltransferase V (β3GalT5) in breast cancer., PMID:30808745
Differential Methylation of H3K79 Reveals DOT1L Target Genes and Function in the Cerebellum In Vivo., PMID:30302725
The response to neoadjuvant chemoradiotherapy with 5-fluorouracil in locally advanced rectal cancer patients: a predictive proteomic signature., PMID:29681787
GWAS on prolonged gestation (post-term birth): analysis of successive Finnish birth cohorts., PMID:29018042
High expression FUT1 and B3GALT5 is an independent predictor of postoperative recurrence and survival in hepatocellular carcinoma., PMID:28883415
Characterization of H type 1 and type 1 N-acetyllactosamine glycan epitopes on ovarian cancer specifically recognized by the anti-glycan monoclonal antibody mAb-A4., PMID:28167527
Unexpected distribution of CA19.9 and other type 1 chain Lewis antigens in normal and cancer tissues of colon and pancreas: Importance of the detection method and role of glycosyltransferase regulation., PMID:27535614
Stage-specific embryonic antigen-3 (SSEA-3) and β3GalT5 are cancer specific and significant markers for breast cancer stem cells., PMID:26677875
A Panel of Recombinant Mucins Carrying a Repertoire of Sialylated O-Glycans Based on Different Core Chains for Studies of Glycan Binding Proteins., PMID:26274979
Control of Glycosylation-Related Genes by DNA Methylation: the Intriguing Case of the B3GALT5 Gene and Its Distinct Promoters., PMID:25256425
Transcriptional control of the B3GALT5 gene by a retroviral promoter and methylation of distant regulatory elements., PMID:24128890
CA19.9 antigen circulating in the serum of colon cancer patients: where is it from?, PMID:23333853
Decreased salivary sulphotransferase activity correlated with inflammation and autoimmunity parameters in Sjogren's syndrome patients., PMID:22101162
DNA methylation and histone modifications modulate the β1,3 galactosyltransferase β3Gal-T5 native promoter in cancer cells., PMID:22001559
Mucosal gene expression profiles following the colonization of immunocompetent defined-flora C3H mice with Helicobacter bilis: a prelude to typhlocolitis., PMID:19397886
Beta1,3-galactosyltransferases-4/5 are novel tumor markers for gynecological cancers., PMID:19225246
Enhanced expression of beta 3-galactosyltransferase 5 activity is sufficient to induce in vivo synthesis of extended type 1 chains on lactosylceramides of selected human colonic carcinoma cell lines., PMID:19136585
Fold-recognition and comparative modeling of human beta3GalT I, II, IV, V and VI and beta3GalNAcT I: prediction of residues conferring acceptor substrate specificity., PMID:17212986
Comprehensive enzymatic characterization of glycosyltransferases with a beta3GT or beta4GT motif., PMID:17113861
Comparative analysis of retroviral and native promoters driving expression of beta1,3-galactosyltransferase beta3Gal-T5 in human and mouse tissues., PMID:17107959
Glycosyltransferases involved in type 1 chain and Lewis antigen biosynthesis exhibit glycan and core chain specificity., PMID:16484342
Endogenous retrovirus long terminal repeats as ready-to-use mobile promoters: the case of primate beta3GAL-T5., PMID:16112824
A high proportion of chromosome 21 promoter polymorphisms influence transcriptional activity., PMID:15200235
For research use only. Not for human or drug use.
