Catalog No.
YHJ84501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys143
Predicted molecular weight
19.29 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y243
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PKBG, PKB gamma, AKT3, STK-2, Protein kinase B gamma, RAC-PK-gamma, RAC-gamma serine/threonine-protein kinase, Protein kinase Akt-3
Deficiency in N-cadherin-Akt3 signaling impairs the blood-brain barrier., PMID:40503940
Dose-dependent immunotoxic mechanisms of celastrol via modulation of the PI3K-Akt signaling pathway., PMID:40495892
Anti-GBM effects of polyphenolic extract from Avicennia marina., PMID:40490234
Mutational analysis and protein expression of PI3K/AKT pathway in four mucinous cystadenocarcinoma of the breast., PMID:40437613
Guanidinoacetic Acid and Methionine Supplementation Improve the Growth Performance of Beef Cattle via Regulating the Antioxidant Levels and Protein and Lipid Metabolisms in Serum and Liver., PMID:40427441
TP53 Mutations and Phosphatidylinositol 3-Kinase/AKT Pathway Alterations Are Key Determinants of Breast Cancer Outcome Independent of Subtype and Stage., PMID:40403210
Integrated transcriptomics and metabolomics unravel the key metabolic pathways involved in the therapeutic mechanism of Salvianic acid A against hepatic fibrosis., PMID:40389097
Whole-Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib., PMID:40388487
Establishment and validation of a novel risk model based on PANoptosis-related genes to predict prognosis in head and neck squamous cell carcinoma., PMID:40324259
Clinical-Genetic Approach to Conditions with Macrocephaly and ASD/Behaviour Abnormalities: Variants in PTEN and PPP2R5D Are the Most Recurrent Gene Mutations in a Patient-Oriented Diagnostic Strategy., PMID:40282429
Identification of biomarkers associated with M1 macrophages in the ST-segment elevation myocardial infarction through bioinformatics and machine learning approaches., PMID:40169697
Cyclic di-AMP alleviates periodontitis by activating PI3K/Akt/Nrf2 pathways., PMID:40160469
Expanding the SIAH1-Associated Phenotypic Spectrum: Insights From Loss-of-Function Variants., PMID:40156476
Differential gene expression in uterine endometrioid cancer cells and adjusted normal tissue., PMID:40090626
Single-cell analysis reveals transcriptomic features and therapeutic targets in primary pulmonary lymphoepithelioma-like carcinoma., PMID:40057671
Functional verification and allele-specific silencing of a novel AKT3 variant that causes megalencephaly, polymicrogyria and intractable epilepsy., PMID:40057591
Akt3 links mitochondrial function to the regulation of Aurora B and mitotic fidelity., PMID:40048438
The phenotypic and genetic spectrum of AKT3-related neurodevelopmental condition., PMID:40032969
AKT activation triggers Rab14-mediated ADAM10 translocation to the cell surface in human aortic endothelial cells., PMID:40032916
Comprehensive analysis of the potential mechanism of gansui in blocking non-small cell lung cancer progression., PMID:40029169
CircAKT3 promotes prostate cancer proliferation and metastasis by enhancing the binding of RPS27A and RPL11., PMID:39994725
Identification and Functional Analysis of Key microRNAs in the Early Extrauterine Environmental Adaptation of Piglets., PMID:39941084
LncRNA UCA1 regulates immune micro-environment in cisplatin-induced AKI by miRNA-4498/AKT3 pathway., PMID:39937792
MyD88 inhibitor TJ-M2010-5 alleviates spleen impairment and inflammation by inhibiting the PI3K/miR-136-5p/AKT3 pathway in the early infection of Trichinella spiralis., PMID:39905552
Structural requirements of isoform-specific inhibitors of Akt: Implications in the development of effective cancer treatment strategies., PMID:39904143
SP1 activates AKT3 to facilitate the development of diabetic nephropathy., PMID:39786707
Ginsenoside Rh2 promotes cell apoptosis in T-cell acute lymphocytic leukaemia by MAPK and PI3K/AKT signalling pathways., PMID:39709631
AXL-TBK1 driven AKT3 activation promotes metastasis., PMID:39689180
Proteomic dataset of knockdown of AKT3 on protein expression and function in female germline stem cells., PMID:39687386
Exploring New and Promising Genetic Biomarkers for Evaluating Traumatic Brain Injuries: A Case-Control Study., PMID:39641810
[Differential expression profile of miRNAs in maternal amniotic fluid exosomes in fetuses with isolated ventriculomegaly]., PMID:39623283
Analysis of 1386 epileptogenic brain lesions reveals association with DYRK1A and EGFR., PMID:39616148
Multimorbidity is associated with myocardial DNA damage, nucleolar stress, dysregulated energy metabolism, and senescence in cardiovascular disease., PMID:39604391
Microarray Analysis of Visceral Adipose Tissue in Obese Women Reveals Common Crossroads Among Inflammation, Metabolism, Addictive Behaviors, and Cancer: AKT3 and MAPK1 Cross Point in Obesity., PMID:39484291
Multi-disciplinary team approach for pediatric hemimegalencephaly: Insights from a single institutional case series., PMID:39442533
Rare CCND2 (p.Thr280Ile) Variant Associated With Infantile Spasms in a Patient With Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome., PMID:39395260
STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation., PMID:39367511
The study on the mechanism of miR-29a in SPPV infection., PMID:39357255
Presence of RB1 or Absence of LRP1B Mutation Predicts Poor Overall Survival in Patients with Gastric Neuroendocrine Carcinoma and Mixed Adenoneuroendocrine Carcinoma., PMID:39327909
c-Myc, AKT, Hsc70, and the T-Box Transcription Factor TBX3 Form an Important Oncogenic Signaling Axis in Breast Cancer., PMID:39264104
PA-MSHA exerts potent activity against cetuximab-resistant colorectal cancer through the miR-7-5p/Akt3/Wnt-β-catenin pathway., PMID:39262485
Integrated analyses of 5 mC, 5hmC methylation and gene expression reveal pathology-associated AKT3 gene and potential biomarkers for Alzheimer's disease., PMID:39197298
Exploring SALL4 as a significant prognostic marker in breast cancer and its association with progression pathways involved in cancer genesis., PMID:39098137
Exosomal MicroRNAs modulate the cognitive function in fasudil treated APPswe/PSEN1dE9 transgenic (APP/PS1) mice model of Alzheimer's disease., PMID:39088109
Differential response of IgM and IgG memory B cell populations to CD40L: insights of T cell - memory B cell interactions., PMID:39050849
Effect and mechanism of Jinkui Shenqi Pill on preventing neural tube defects in mice based on network pharmacology., PMID:39025160
NTRK-fused central nervous system tumours: clinicopathological and genetic insights and response to TRK inhibitors., PMID:39014476
Lysophosphatidylcholines Promote Influenza Virus Reproduction through the MAPK/JNK Pathway in PMA-Differentiated THP-1 Macrophages., PMID:38928244
Down-Regulation of AKT Proteins Slows the Growth of Mutant-KRAS Pancreatic Tumors., PMID:38920688
Autophagic degradation of DHCR7 activates AKT3 and promotes sevoflurane-induced hippocampal neuroinflammation in neonatal mice., PMID:38901498
For research use only. Not for human or drug use.
