Catalog No.
YHJ84401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala22-Phe323
Predicted molecular weight
60.37 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y240
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
p47, Lymphocyte secreted C-type lectin, CLECSF3, CLEC11A, Stem cell growth factor, SCGF, Osteolectin, C-type lectin superfamily member 3, LSLCL, C-type lectin domain family 11 member A
Potential drug targets for Neuromyelitis optica spectrum disorders (NMOSD): A Mendelian randomization analysis., PMID:40294019
Potential drug targets for ovarian cancer identified through Mendelian randomization and colocalization analysis., PMID:39972314
CLEC11A-Driven Molecular Mechanisms in Intervertebral Disc Degeneration: A Comprehensive Multi-Omics Study., PMID:39897524
The role of Clec11a in bone construction and remodeling., PMID:39188913
Comparing machine learning screening approaches using clinical data and cytokine profiles for COVID-19 in resource-limited and resource-abundant settings., PMID:38937503
Utility of methylated DNA markers for the diagnosis of malignant biliary strictures., PMID:38905442
Genetic insight into putative causes of xanthelasma palpebrarum: a Mendelian randomization study., PMID:38601164
CLEC11A methylation is correlated to AML subtypes and cytogenetic risk factors but not patient demographics., PMID:38466706
Identification and characterization of CLEC11A and its derived immune signature in gastric cancer., PMID:38348052
Ultrasensitive and Quantitative DNA Methylation Detection Method Based on the MutS Protein., PMID:38078896
Single-cell analysis reveals altered tumor microenvironments of relapse- and remission-associated pediatric acute myeloid leukemia., PMID:37798266
CLEC11A expression as a prognostic biomarker in correlation to immune cells of gastric cancer., PMID:37597212
CLEC11A improves insulin secretion and promotes cell proliferation in human beta-cells., PMID:37078556
Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients., PMID:36305631
Identification of Significant Secreted or Membrane-Located Proteins in Laryngeal Squamous Cell Carcinoma., PMID:35655921
Daidzein Activates Akt Pathway to Promote the Proliferation of Female Germline Stem Cells through Upregulating Clec11a., PMID:35655001
Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4)., PMID:35640156
Cerebrospinal Fluid in Classical Trigeminal Neuralgia: An Exploratory Study on Candidate Biomarkers., PMID:35625736
Endothelial dysfunction contributes to severe COVID-19 in combination with dysregulated lymphocyte responses and cytokine networks., PMID:34893580
The effect of parathyroid hormone on osteogenesis is mediated partly by osteolectin., PMID:34140410
Measurement of multiple cytokines for discrimination and risk stratification in patients with Chagas' disease and idiopathic dilated cardiomyopathy., PMID:33755669
A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis., PMID:33627868
Identification of Fibroblast Activation Protein as an Osteogenic Suppressor and Anti-osteoporosis Drug Target., PMID:33053358
The identification of articular cartilage and growth plate extracellular matrix-specific proteins supportive of either osteogenesis or stable chondrogenesis of stem cells., PMID:32473752
Identification and validation of a prognostic 8-gene signature for acute myeloid leukemia., PMID:32268820
Human umbilical cord mesenchymal stromal cells-derived extracellular vesicles exert potent bone protective effects by CLEC11A-mediated regulation of bone metabolism., PMID:32089743
Molecular structure, expression, and functional role of Clec11a in skeletal biology and cancers., PMID:32003015
Protective effects of Clec11a in islets against lipotoxicity via modulation of proliferation and lipid metabolism in mice., PMID:31494095
Targeted genetic screening in mice through haploid embryonic stem cells identifies critical genes in bone development., PMID:31265461
Identification of a mesenchymal progenitor cell hierarchy in adipose tissue., PMID:31023895
[Construction and analysis of gene co-expression networks in intracranial aneurysm]., PMID:30786351
Integrin alpha11 is an Osteolectin receptor and is required for the maintenance of adult skeletal bone mass., PMID:30632962
A novel scoring system for acute myeloid leukemia risk assessment based on the expression levels of six genes., PMID:29956722
Cerebrospinal Fluid Cytokine Expression Profile in Multiple Sclerosis and Chronic Inflammatory Demyelinating Polyneuropathy., PMID:29182448
Clec11a/osteolectin is an osteogenic growth factor that promotes the maintenance of the adult skeleton., PMID:27976999
Whole Chromosome Instability induces senescence and promotes SASP., PMID:27731420
Chemokines involved in the early inflammatory response and in pro-tumoral activity in asbestos-exposed workers from an Italian coastal area with territorial clusters of pleural malignant mesothelioma., PMID:26973208
Elevated levels of endothelial-derived microparticles, and serum CXCL9 and SCGF-β are associated with unstable asymptomatic carotid plaques., PMID:26564003
Exploratory study for identifying systemic biomarkers that correlate with pain response in patients with intervertebral disc disorders., PMID:26440592
Pilot study: elevated circulating levels of the proinflammatory cytokine macrophage migration inhibitory factor in patients with chronic spinal cord injury., PMID:23618747
Prognostic value of circulating levels of stem cell growth factor beta (SCGF beta) in patients with Chagas' disease and idiopathic dilated cardiomyopathy., PMID:23357302
Proteomic detection of a large amount of SCGFα in the stroma of GISTs after imatinib therapy., PMID:21943129
A novel functional variant in the stem cell growth factor promoter protects against severe malarial anemia., PMID:19884328
Suppression of a novel hematopoietic mediator in children with severe malarial anemia., PMID:19528216
Association study between keratinocyte-derived growth factor gene polymorphisms and susceptibility to vitiligo vulgaris in a Taiwanese population: potential involvement of stem cell factor., PMID:19416273
Leukemia cell lines require self-secreted stem cell growth factor (SCGF) for their proliferation., PMID:18289675
Identification of the adult human hemangioblast., PMID:15186719
Stem cell growth factor: in situ hybridization analysis on the gene expression, molecular characterization and in vitro proliferative activity of a recombinant preparation on primitive hematopoietic progenitor cells., PMID:11920266
Expression of LSLCL, a new C-type lectin, is closely restricted, in bone marrow, to immature neutrophils., PMID:11803813
Cloning, mapping, and genomic organization of the LSLCL gene, encoding a new lymphocytic secreted mucin-like protein with a C-type lectin domain: A new model of exon shuffling., PMID:10198175
For research use only. Not for human or drug use.
