Catalog No.
YHJ84301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala612-Asp826
Predicted molecular weight
26.49 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y239
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NOD1, Nucleotide-binding oligomerization domain-containing protein 1, Caspase recruitment domain-containing protein 4, CARD4
Chlamydia trachomatis restricts signaling through NOD2 until late in the pathogen's developmental cycle., PMID:40502116
Inhibition of the NLR pathway alleviates MAPK1 mutation-driven proliferation and differentiation deficits and enhanced apoptosis in P19 cells., PMID:40466562
Role of NLRC3 in modulating inflammatory responses in neonates., PMID:40437402
A nod to paratuberculosis: NOD1 and NOD2 expression in the pathological spectrum of Mycobacterium avium subsp. paratuberculosis infection in cattle., PMID:40433460
The immune system in cardiovascular diseases: from basic mechanisms to therapeutic implications., PMID:40404619
NOD1 deficiency promotes inflammation via autophagic degradation of ASK1., PMID:40399666
Probiotic Bactolac alleviates depression-like behaviors by modulating BDNF, NLRP3 and MC4R levels, reducing neuroinflammation and promoting neural repair in rat model., PMID:40281288
Differential immunoregulation by human surfactant protein A variants determines severity of SARS-CoV-2-induced lung disease., PMID:40242753
Molecular Identification and Expression Analysis of NOD1/2 and TBK1 in Response to Viral or Bacterial Infection in the Spotted Knifejaw (Oplegnathus punctatus)., PMID:40218399
NLRs in tumor chemotherapy resistance: A double-edged sword., PMID:40180110
Topical administration of coumarin derivatives alleviates skin inflammatory symptoms in atopic dermatitis model., PMID:40157005
Ubiquitin Ligases in Control: Regulating NLRP3 Inflammasome Activation., PMID:40152367
The changes of NLRs family members in the brain of AD mouse model and AD patients., PMID:40066444
Porphyromonas gingivalis potentiates stem-like properties of oral squamous cell carcinoma by modulating SCD1-dependent lipid synthesis via NOD1/KLF5 axis., PMID:40016182
Promising Antidepressant Potential: The Role of Lactobacillus rhamnosus GG in Mental Health and Stress Response., PMID:39962033
[Analgesic effect of "Zhibian" (BL54)-toward-"Shuidao" (ST28) needling technique of acupuncture on primary dysmenorrhea based on NOD1/RIP2/NF-κB signaling pathway in the rats]., PMID:39943763
NOD1: a metabolic modulator., PMID:39906040
DAMPs prognostic signature predicts tumor immunotherapy, and identifies immunosuppressive mechanism of pannexin 1 channels in pancreatic ductal adenocarcinoma., PMID:39882247
Expression profiles of NOD1 and NOD2 and pathological changes in gills during Flavobacterium columnare infection in yellow catfish, Tachysurus fulvidraco., PMID:39876057
Evolutionary trajectories of immune escape across cancers., PMID:39868264
High expression of nucleotide-binding oligomerization domain protein 1 correlates with poor prognosis and immune cell infiltration in Glioblastoma Multiforme patients., PMID:39798050
Structural Characterization and Immune Activation Capacity of Peptidoglycan from Corynebacterium glutamicum in RAW264.7 Cells., PMID:39796098
Knockdown of GSDMD inhibits pyroptosis in psoriasis by blocking the NOD-like receptor signaling pathway., PMID:39778279
Aging Selectively Alters PRR and ISG Expression in Endo- and Ecto-Cervical Stromal Fibroblasts From the Human Female Reproductive Tract., PMID:39777771
Lactobacillus intestinalis facilitates tumor-derived CCL5 to recruit dendritic cell and suppress colorectal tumorigenesis., PMID:39773173
Cancer-Associated Fibroblast-Secreted Exosomes Regulate Macrophage Polarization in Pancreatic Cancer via the NOD1 Pathway., PMID:39756063
Exploring the Impact of Amidation Status in Meso-Diaminopimelic-Acid-Containing Disaccharide Peptidoglycan Fragments on Host Innate Immune Activation., PMID:39749870
Revealing NOD1-Activating Gram-Positive Gut Microbiota via in Vivo Labeling with a meso-Diaminopimelic Acid Probe., PMID:39745661
Vi capsular polysaccharide of Salmonella enterica serovar Typhi disturbs autophagy to increase intracellular survival in macrophages., PMID:39732413
Inducing phospholipase A2 and cyclooxygenase-2 expression and prostaglandins' production of human dental pulp cells by activation of NOD receptor and its downstream signaling., PMID:39730047
Nucleotide-binding oligomerization domain 1 (NOD1) regulates microglial activation in pseudorabies virus infection., PMID:39696641
NOD1 signaling regulates early tissue inflammation during helminth infection., PMID:39662675
Microcystin-LR induces fatty liver metabolic disease in zebrafish through the PPARα-NOD1 pathway: In vivo, in vitro, and in silico investigations., PMID:39657491
Semen extender triggers a mild physiological inflammatory response in the uterus without disrupting sperm-uterine immune crosstalk in vitro in cattle., PMID:39647914
Macrophage Dvl2 deficiency promotes NOD1-Driven pyroptosis and exacerbates inflammatory liver injury., PMID:39644526
Role of the NOD1/Rip2 Signaling Pathway in Macrophage Inflammatory Activation Induced by ox-LDL., PMID:39640499
Selectively Antagonizing the NOD1-Mediated Inflammatory Signaling Pathway Mitigates the Gastric Inflammation Induced by Helicobacter pylori Infection., PMID:39637404
Taurine potentiates artemisinin efficacy against malaria by modulating the immune response in Plasmodium berghei-infected mice., PMID:39614280
NOD1 Agonist Induces Proliferation and Plasma Cell Differentiation of Mouse B Cells Especially CD23high B Cells., PMID:39560184
RIPK2 Is Crucial for the Microglial Inflammatory Response to Bacterial Muramyl Dipeptide but Not to Lipopolysaccharide., PMID:39519307
Profiling of Potential Anti-Diabetic Active Compounds in White Tea: An Integrated Study of Polyphenol-Targeted Metabolomics, Network Pharmacology, and Computer Simulation., PMID:39517138
Silencing CCT3 induces ferroptosis through the NOD1-NF-κB signaling pathway in bladder cancer., PMID:39478031
Arginine alleviates LPS-induced leukocytes inflammation and apoptosis via adjusted NODs signaling., PMID:39461398
Chidan Tuihuang granule modulates gut microbiota to influence NOD1/RIPK2 pathway in cholestatic liver injury recovery., PMID:39461197
4-Anilinoquinazoline Derivatives as the First Potent NOD1-RIPK2 Signaling Pathway Inhibitors at the Nanomolar Range., PMID:39444201
ER stress aggravates NOD1-mediated inflammatory response leading to impaired nutrient metabolism in hepatoma cells., PMID:39423570
RIPK2 is crucial for the microglial inflammatory response to bacterial muramyl dipeptide but not to lipopolysaccharide., PMID:39416057
Towards New Anti-Inflammatory Agents: Design, Synthesis and Evaluation of Molecules Targeting XIAP-BIR2., PMID:39364702
Activation of NOD1 on tumor-associated macrophages augments CD8+ T cell-mediated antitumor immunity in hepatocellular carcinoma., PMID:39356756
A genome-wide CRISPR/Cas9 knockout screen identifies SEMA3F gene for resistance to cyclin-dependent kinase 4 and 6 inhibitors in breast cancer., PMID:39352623
For research use only. Not for human or drug use.
