Catalog No.
YHJ82801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu6-Ser290
Predicted molecular weight
34.42 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UPY3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DICER, DICER1, Helicase MOI, Endoribonuclease Dicer, Helicase with RNase motif, HERNA, KIAA0928
[DICER1-mutant primary intracranial sarcoma: analysis of five cases]., PMID:40494768
Targeting Dicer reprograms tumor-associated macrophages to promote anti-tumoral immunity in colorectal cancer liver metastasis., PMID:40481520
Focal High-Grade Areas with a Tumor-in-Tumor Pattern: Another Feature of Pediatric DICER1-Associated Thyroid Carcinoma?, PMID:40448797
Characteristics of the MicroRNA-Processing Enzymes in Melanocytic Skin Lesions: Dicer and DGCR8 Are Potential Biomarkers for Primary Cutaneous Melanomas., PMID:40344283
[Cytopathological features of thyroid tumors with DICER1 mutation]., PMID:40302583
Pathological and clinical insights into DICER1 hotspot mutated Sertoli-Leydig cell tumors: a comparative analysis., PMID:40301978
MiR-125/let-7 cluster orchestrates neuronal cell fate determination and cortical layer formation during neurogenesis., PMID:40300336
Prognostic Significance of Germline DICER1 Pathogenic or Likely Pathogenic Variants in Outcomes of Ovarian Sertoli-Leydig Cell Tumor., PMID:40267387
An imbalance between proliferation and differentiation underlies the development of microRNA-defective pineoblastoma., PMID:40240142
Intron Variant Cause DICER1 Syndrome With Pleuropulmonary Blastoma., PMID:40226310
Dicer deficiency affects microglial function during demyelination and impairs remyelination., PMID:40120829
A Novel Pathogenic Variant of DICER1 Gene in a Young Greek Patient with 2 Different Sex-Cord Ovarian Tumors and Multinodular Goiter., PMID:40076617
Neutrophil-modulated Dicer expression in macrophages influences inflammation resolution., PMID:40074991
Dicer Loss in Müller Glia Leads to a Defined Sequence of Pathological Events Beginning With Cone Dysfunction., PMID:40035725
[Clinicopathological significance of DICER1 mutation in follicular thyroid carcinoma]., PMID:40032416
SFTSV NSs interacts with AGO2 to regulate the RNAi pathway for viral replication., PMID:40013801
Germline Pathogenic DROSHA Variants Are Linked to Pineoblastoma and Wilms Tumor Predisposition., PMID:39992227
A double-edged sword in antiviral defence: ATG7 binding dicer to promote virus replication., PMID:39985575
Competition effects regulating the composition of the microRNA pool., PMID:39965642
Alternative driver pathways in peripheral nerve sheath tumors - including DICER1 and/or KRAS alterations., PMID:39846292
Multi-miRNAs-Mediated Hepatic Lepr Axis Suppression: A Pparg-Dicer1 Pathway-Driven Mechanism in Spermatogenesis for the Intergenerational Transmission of Paternal Metabolic Syndrome., PMID:39792613
Enhanced RNAi does not provide efficient innate antiviral immunity in mice., PMID:39778869
The changes in the ratio of Dicer1 transcripts can participate in the neuronal hypoxic response by regulating miR-29b., PMID:39756430
Effectiveness and Impact of Transcript Analysis in Clinical Genetics Daily Practice., PMID:39707869
Pleuropulmonary blastoma and DICER1-related tumor predisposition: from clinicopathologic observations to clinical trial., PMID:39699100
The human Dicer helicase domain is capable of ATP hydrolysis and single-stranded nucleic acid binding., PMID:39695695
[Primary intracranial DICER1-mutant sarcoma: a clinicopathological analysis of seven cases]., PMID:39648006
Clinicopathologic and Molecular Analysis of 15 Pediatric and Young Adult Patients with High-Grade Non-anaplastic Thyroid Carcinoma., PMID:39636536
A novel pathogenic DICER1 gene variant is associated with hereditary multinodular goiter in an Argentine family as evidenced by clinical, biochemical and molecular genetic analysis., PMID:39607641
MicroRNA regulator gene mutations in thyroid follicular nodular disease and thyroid cancer: does it all come down to timing?, PMID:39601261
Whole genome profiling of rare pediatric thoracic tumors elucidates a YAP1::LEUTX fusion in an unclassified biphasic embryonal neoplasm., PMID:39566337
Behavioural phenotypes of Dicer knockout in the mouse SCN., PMID:39551620
Update on Pediatric Surveillance Recommendations for PTEN Hamartoma Tumor Syndrome, DICER1-Related Tumor Predisposition, and Tuberous Sclerosis Complex., PMID:39540884
Rapid downregulation of DICER is a hallmark of adipose tissue upon high-fat diet feeding., PMID:39536934
Primary intracranial sarcoma associated with DICER1 mutant: a case report and preclinical investigation., PMID:39522081
The Role of Dicer Phosphorylation in Gemcitabine Resistance of Pancreatic Cancer., PMID:39519347
Somatic DICER1-Mutant Benign Thyroid Nodules in Adults: A Group of Follicular Nodular Disease With Continuous Growth., PMID:39468764
MicroRNA and Rare Human Diseases., PMID:39457367
LINC00365 promotes miR-221-5p to inhibit pyroptosis via Dicer in colorectal cancer., PMID:39439418
UVB radiation suppresses Dicer expression through β-catenin., PMID:39439393
Determinants of selectivity in the dicing mechanism., PMID:39420173
Understanding the Dosage-Dependent Role of Dicer1 in Thyroid Tumorigenesis., PMID:39409030
Establishment and Characterization of a Novel Pleuropulmonary Blastoma Cell Line., PMID:39400393
DICER1-Related Tumor Predisposition: Identification of At-risk Individuals and Recommended Surveillance Strategies., PMID:39400264
DICER1 Variants in Pediatric and Young Adult Thyroid Nodules., PMID:39283830
The coexistence of a BRCA2 germline and a DICER1 somatic variant in two first-degree cousins suggests their potential synergic effect., PMID:39271738
Botryoid-type Embryonal Rhabdomyosarcoma: A Comprehensive Clinicopathologic and Molecular Appraisal With Cross-comparison to its Conventional-type Counterpart., PMID:39210566
Gene Variants in Components of the microRNA Processing Pathway in Chronic Myeloid Leukemia., PMID:39202414
SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia., PMID:39138195
DICER1-sarcomas of GYN tract: Expanding on an emerging entity., PMID:39127354
For research use only. Not for human or drug use.
