Catalog No.
YHJ82501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln117-Trp322
Predicted molecular weight
25.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UP38
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FzE1, Frizzled-1, hFz1, Fz-1, FZD1
WNT Mimetic-Induced Lacrimal Gland Regeneration Reverses Aqueous Tear Deficiency., PMID:40492997
FZD5 controls intestinal crypt homeostasis and colonic Wnt surrogate agonist response., PMID:39579768
Genetic Differences between Male and Female Pattern Hair Loss in a Korean Population., PMID:39202681
A novel drug prejudice scaffold-imidazopyridine-conjugate can promote cell death in a colorectal cancer model by binding to β-catenin and suppressing the Wnt signaling pathway., PMID:39067696
Delta-like noncanonical notch ligand 2 regulates the proliferation and differentiation of sheep myoblasts through the Wnt/β-catenin signaling pathway., PMID:39030845
E3 ligases RNF43 and ZNRF3 display differential specificity for endocytosis of Frizzled receptors., PMID:38969364
Urine Proteomic Signatures of Mild Hypothermia Treatment in Cerebral Ischemia-Reperfusion Injury in Rats., PMID:38836960
Single-cell RNA-seq analysis reveals the Wnt/Ca2+ signaling pathway with inflammation, apoptosis in nucleus pulposus degeneration., PMID:38654287
Frizzled receptors (FZDs) in Wnt signaling: potential therapeutic targets for human cancers., PMID:38632318
A WNT mimetic with broad spectrum FZD-specificity decreases fibrosis and improves function in a pulmonary damage model., PMID:38566174
Spatial gene expression profile of Wnt-signaling components in the murine enteric nervous system., PMID:38322254
Structural and functional insight into the interaction of Clostridioides difficile toxin B and FZD7., PMID:38308843
A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways., PMID:38182578
The Wnt/β-catenin pathway is involved in 2,5-hexanedione-induced ovarian granulosa cell cycle arrest., PMID:37995618
Transcriptome profile of reserpine-induced locomotor behavioral changes in zebrafish (Danio rerio)., PMID:37839537
C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation., PMID:37699522
Genome-wide DNA methylation and transcriptome expression profiles of peripheral blood mononuclear cells in patients with systemic sclerosis with interstitial lung disease., PMID:37587067
Encapsulation of MCC950 in Liposomes Decorated with Anti-Frizzled 1 Improves Drug Bioavailability and Effectiveness in Fatty Liver Disease., PMID:37417887
Novel Frizzled-specific antibody-based Wnt mimetics and Wnt superagonists selectively activate WNT/β-catenin signaling in target tissues., PMID:37413985
Targeted alveolar regeneration with Frizzled-specific agonists., PMID:37321220
An in-silico approach to understand the potential role of Wnt inhibitory factor-1 (WIF-1) in the inhibition of the Wnt signalling pathway., PMID:36995086
FZD1/KLF10-hsa-miR-4762-5p/miR-224-3p-circular RNAs axis as prognostic biomarkers and therapeutic targets for glioblastoma: a comprehensive report., PMID:36755291
Enhancer trap lines with GFP driven by smad6b and frizzled1 regulatory sequences for the study of epithelial morphogenesis in the developing zebrafish inner ear., PMID:36748120
Continuous exposure to alpha-glycosyl isoquercitrin from mid-gestation ameliorates polyinosinic-polycytidylic acid-disrupted hippocampal neurogenesis in rats., PMID:36572259
Molecular characterization of early breast cancer onset to understand disease phenotypes in African patients., PMID:36352274
GPER Agonist G1 Prevents Wnt-Induced JUN Upregulation in HT29 Colorectal Cancer Cells., PMID:36293473
Cell cultures in assessing radioresistance of glioblastomas., PMID:36252203
Effects of Triiodothyronine on Human Osteoblast-Like Cells: Novel Insights From a Global Transcriptome Analysis., PMID:35784485
Euphorbiasteroid Abrogates EGFR and Wnt/β-Catenin Signaling in Non-Small-Cell Lung Cancer Cells to Impart Anticancer Activity., PMID:35744950
Multiple roles for Bcl-3 in mammary gland branching, stromal collagen invasion, involution and tumor pathology., PMID:35681213
FOXF2 oppositely regulates stemness in luminal and basal-like breast cancer cells through the Wnt/beta-catenin pathway., PMID:35660418
Functional role of the Frizzled linker domain in the Wnt signaling pathway., PMID:35513706
Fos-Related Antigen 1 May Cause Wnt-Fzd Signaling Pathway-Related Nephroblastoma in Children., PMID:35484756
Epigenetic repression of Wnt receptors in AD: a role for Sirtuin2-induced H4K16ac deacetylation of Frizzled1 and Frizzled7 promoters., PMID:35296808
[RBM38 Mediates the Proliferation of Acute Myeloid Leukemia Cells HL-60 by Regulating FZD1 mRNA Stability]., PMID:34893109
Protein disulfide isomerase family 6 promotes the imatinib-resistance of renal cell carcinoma by regulation of Wnt3a-Frizzled1 axis., PMID:34781823
Determining oncogenic patterns and cancer predisposition through the transcriptomic profile in Mitchell-Riley syndrome with heterotopic gastric mucosa and duodenal atresia: a case report., PMID:34715892
Cardiomyocyte-specific deletion of β-catenin protects mouse hearts from ventricular arrhythmias after myocardial infarction., PMID:34489488
Oligodendroglial ring finger protein Rnf43 is an essential injury-specific regulator of oligodendrocyte maturation., PMID:34390652
LINC00942 Promotes Tumor Proliferation and Metastasis in Lung Adenocarcinoma via FZD1 Upregulation., PMID:34253104
Wingless-type mouse mammary tumor virus integration site regulation of bovine theca cells., PMID:34166505
Expression and prognostic impact of FZDs in pancreatic adenocarcinoma., PMID:33618667
WNT-FRIZZLED-LRP5/6 Signaling Mediates Posterior Fate and Proliferation during Planarian Regeneration., PMID:33467529
Expression analysis of chick Frizzled receptors during spinal cord development., PMID:33460819
A Simple RFLP-Based Method for HFE Gene Multiplex Amplification and Determination of Hereditary Hemochromatosis-Causing Mutation C282Y and H63D Variant with Highly Sensitive Determination of Contamination., PMID:33457423
FOLFOX Therapy Induces Feedback Upregulation of CD44v6 through YB-1 to Maintain Stemness in Colon Initiating Cells., PMID:33451103
Hypoxia-Induced Suppression of Alternative Splicing of MBD2 Promotes Breast Cancer Metastasis via Activation of FZD1., PMID:33402389
Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions., PMID:33236989
Dynamic changes in chromatin accessibility, altered adipogenic gene expression, and total versus de novo fatty acid synthesis in subcutaneous adipose stem cells of normal-weight polycystic ovary syndrome (PCOS) women during adipogenesis: evidence of cellular programming., PMID:33228780
lncRNA VIM‑AS1 promotes cell proliferation, metastasis and epithelial‑mesenchymal transition by activating the Wnt/β‑catenin pathway in gastric cancer., PMID:33173977
For research use only. Not for human or drug use.
