Catalog No.
YHJ80101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1031-Arg1270
Predicted molecular weight
30.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9ULD2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
AT2 receptor-binding protein, Angiotensin-II type 2 receptor-interacting protein, ATBP, Mitochondrial tumor suppressor 1, MTSG1, MTUS1, ATIP, Microtubule-associated tumor suppressor 1, GK1, KIAA1288
ATIP1 Is a Suppressor of Cardiac Hypertrophy and Modulates AT2-Dependent Signaling in Cardiac Myocytes., PMID:40358169
The Role of the MTUS1 Gene in the Development of Left Ventricular Noncompaction Cardiomyopathy-A Case Report., PMID:40004439
FTO-mediated demethylation of MTUS1/ATIP1 promotes tumor progression in head and neck squamous cell carcinoma., PMID:39627705
Mitochondrial outer membrane protein MTUS1/ATIP1 exerts antitumor effects through ROS-induced mitochondrial pyroptosis in head and neck squamous cell carcinoma., PMID:38725862
[Microtubule-associated tumor suppressor 1 inhibits hemin-induced apoptosis of vascular endothelial cells via hemeoxygenase 1]., PMID:38658371
ATIP/ATIP1 regulates prostate cancer metastasis through mitochondrial dynamic-dependent signaling., PMID:38282475
Correction to: Oncogenic miR-19a and miR-19b co-regulate tumor suppressor MTUS1 to promote cell proliferation and migration in lung cancer., PMID:38217534
Identification of candidate DNA methylation biomarkers related to Alzheimer's disease risk by integrating genome and blood methylome data., PMID:38092781
A Network of 17 Microtubule-Related Genes Highlights Functional Deregulations in Breast Cancer., PMID:37835564
Deep sequencing of circulating miRNAs and target mRNAs level in deep venous thrombosis patients., PMID:37466160
Long Noncoding RNA MIR600HG Binds to MicroRNA-125a-5p to Prevent Pancreatic Cancer Progression Via Mitochondrial Tumor Suppressor 1-Dependent Suppression of Extracellular Regulated Protein Kinases Signaling Pathway., PMID:37099789
Low MTUS1 Protein Expression Is Associated with Poor Survival in Patients with Colorectal Adenocarcinoma., PMID:36980447
MTUS1 is a promising diagnostic and prognostic biomarker for colorectal cancer., PMID:35962436
Identification and validation of HOXD3 and UNC5C as molecular signatures in keloid based on weighted gene co-expression network analysis., PMID:35709926
Modular and mechanistic changes across stages of colorectal cancer., PMID:35448980
A genomic mutation spectrum of collecting duct carcinoma in the Chinese population., PMID:34980126
Correction to: RNA-binding protein SORBS2 suppresses clear cell renal cell carcinoma metastasis by enhancing MTUS1 mRNA stability., PMID:34750363
Neuregulin 1 (NRG1) fusion-positive high-grade spindle cell sarcoma: A distinct group of soft tissue tumors with metastatic potential., PMID:34747541
In silico analysis of deleterious SNPs of human MTUS1 gene and their impacts on subsequent protein structure and function., PMID:34125870
Microtubule-Associated Protein ATIP3, an Emerging Target for Personalized Medicine in Breast Cancer., PMID:34062782
The Tumor Suppressor MTUS1/ATIP1 Modulates Tumor Promotion in Glioma: Association with Epigenetics and DNA Repair., PMID:33809019
RNA-binding protein SORBS2 suppresses clear cell renal cell carcinoma metastasis by enhancing MTUS1 mRNA stability., PMID:33311452
Identification of prognostic genes in uveal melanoma microenvironment., PMID:33196683
Reciprocal regulation of Aurora kinase A and ATIP3 in the control of metaphase spindle length., PMID:32789689
ATIP3 deficiency facilitates intracellular accumulation of paclitaxel to reduce cancer cell migration and lymph node metastasis in breast cancer patients., PMID:32764625
Transcriptional information underlying the generation of CSCs and the construction of a nine-mRNA signature to improve prognosis prediction in colorectal cancer., PMID:32453965
Reduced long non-coding RNA PTENP1 contributed to proliferation and invasion via miR-19b/MTUS1 axis in patients with cervical cancer., PMID:32373949
Clinicopathological Significance of MTUS1 Expression in Patients With Renal Cell Carcinoma., PMID:32366449
From tumorigenesis to cell death: the aneuploidy paradox., PMID:32158924
Loss of MTUS1 Expression Is Associated With Poor Prognosis in Patients With Gallbladder Carcinoma., PMID:31882471
Improving breast cancer sensitivity to paclitaxel by increasing aneuploidy., PMID:31685623
Microtubule-associated tumor suppressors as prognostic biomarkers in breast cancer., PMID:31606824
A de novo Mutation in the MTUS1 Gene Decreases the Risk of Non-compaction of Ventricular Myocardium via the Rac1/Cdc42 Pathway., PMID:31338350
MicroRNA-765 targets MTUS1 to promote the progression of osteosarcoma via mediating ERK/EMT pathway., PMID:31210288
Altered expression profile of circular RNAs in conjunctival melanoma., PMID:30892069
DNA methylation regulates Microtubule-associated tumor suppressor 1 in human non-small cell lung carcinoma., PMID:30528566
Combinatorial expression of microtubule-associated EB1 and ATIP3 biomarkers improves breast cancer prognosis., PMID:30368744
Microtubule associated tumor suppressor 1 interacts with mitofusins to regulate mitochondrial morphology in endothelial cells., PMID:29558204
Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages., PMID:29274321
Angiotensin II type 2 receptor-interacting protein 3a inhibits ovarian carcinoma metastasis via the extracellular HMGA2-mediated ERK/EMT pathway., PMID:28651497
MTUS1, a gene encoding angiotensin-II type 2 (AT2) receptor-interacting proteins, in health and disease, with special emphasis on its role in carcinogenesis., PMID:28499941
Oncogenic miR-19a and miR-19b co-regulate tumor suppressor MTUS1 to promote cell proliferation and migration in lung cancer., PMID:28364280
Activation of the cell membrane angiotensin AT2 receptors in human leiomyosarcoma cells induces differentiation and apoptosis by a PPARγ - dependent mechanism., PMID:28253719
MTUS1 silencing promotes E-selectin production through p38 MAPK-dependent CREB ubiquitination in endothelial cells., PMID:27789289
Identification of the Mtus1 Splice Variant as a Novel Inhibitory Factor Against Cardiac Hypertrophy., PMID:27385424
MTUS1 tumor suppressor and its miRNA regulators in fibroadenoma and breast cancer., PMID:27155522
Angiotensin II type 2 receptor-interacting protein 3a suppresses proliferation, migration and invasion in tongue squamous cell carcinoma via the extracellular signal-regulated kinase-Snai2 pathway., PMID:26870214
Loss of Mitochondrial Tumor Suppressor Genes Expression Is Associated with Unfavorable Clinical Outcome in Head and Neck Squamous Cell Carcinoma: Data from Retrospective Study., PMID:26785117
MTUS1 and its targeting miRNAs in colorectal carcinoma: significant associations., PMID:26643896
Negative regulation of EB1 turnover at microtubule plus ends by interaction with microtubule-associated protein ATIP3., PMID:26498358
For research use only. Not for human or drug use.
