Catalog No.
YHJ79701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn37-Ala269
Predicted molecular weight
26.61 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UKX7
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Nuclear pore complex protein Nup50, 50 kDa nucleoporin, NUP50, Nuclear pore-associated protein 60 kDa-like, NPAP60L, Nucleoporin Nup50
T cell and autoantibody recognition of nucleus-associated islet autoantigens in individuals with type 1 diabetes., PMID:40490584
Transcriptome analysis of different stages of testis development in Portunus trituberculatus., PMID:40010143
TMEM160 Promotes Tumor Growth in Lung Adenocarcinoma and Cervical Adenocarcinoma Cell Lines., PMID:39940865
Nucleoporin Nup98 is an essential factor for ipo4 dependent protein import., PMID:38780165
CircNUP50 is a novel therapeutic target that promotes cisplatin resistance in ovarian cancer by modulating p53 ubiquitination., PMID:38243224
Nuclear pore pathology underlying multisystem proteinopathy type 3-related inclusion body myopathy., PMID:38158701
Nucleoporin 50 proteins affect longevity and salinity stress tolerance in seeds., PMID:37849222
Identification of novel nuclear pore complex associated proteins in esophageal carcinoma by an integrated bioinformatics analysis., PMID:37504972
Integrative genetic analysis illuminates ALS heritability and identifies risk genes., PMID:36670122
SMARCC1 Enters the Nucleus via KPNA2 and Plays an Oncogenic Role in Bladder Cancer., PMID:35669562
Genetic Associations and Differential mRNA Expression Levels of Host Genes Suggest a Viral Trigger for Endemic Pemphigus Foliaceus., PMID:35632621
Nup50 plays more than one instrument., PMID:35549614
Latent Membrane Protein 1 (LMP1) from Epstein-Barr Virus (EBV) Strains M81 and B95.8 Modulate miRNA Expression When Expressed in Immortalized Human Nasopharyngeal Cells., PMID:35205397
The nucleoporin Nup50 activates the Ran guanine nucleotide exchange factor RCC1 to promote NPC assembly at the end of mitosis., PMID:34725842
Distinct roles of nuclear basket proteins in directing the passage of mRNA through the nuclear pore., PMID:34504007
Nucleoporin 50 mediates Kcna4 transcription to regulate cardiac electrical activity., PMID:34409458
Identifying Novel Cell Glycolysis-Related Gene Signature Predictive of Overall Survival in Gastric Cancer., PMID:33791386
A single QTL with large effect is associated with female functional virginity in an asexual parasitoid wasp., PMID:33638236
hsa-miR-191-5p inhibits replication of human immunodeficiency virus type 1 by downregulating the expression of NUP50., PMID:33420627
Nucleoporin TPR is an integral component of the TREX-2 mRNA export pathway., PMID:32917881
XPO1 is a critical player for bortezomib resistance in multiple myeloma: A quantitative proteomic approach., PMID:31465861
[Expression profiles of microRNA in peripheral blood mononuclear cells and immune factors in pregnant women with hepatitis B virus infection]., PMID:31400127
Novel minor HLA DR associated antigens in type 1 diabetes., PMID:29990590
The role of vimentin in the tumor marker Nup88-dependent multinucleated phenotype., PMID:29724197
Nup153 and Nup50 promote recruitment of 53BP1 to DNA repair foci by antagonizing BRCA1-dependent events., PMID:28751496
Localisation of Nup153 and SENP1 to nuclear pore complexes is required for 53BP1-mediated DNA double-strand break repair., PMID:28576968
Aberrant distributions of nuclear pore complex proteins in ALS mice and ALS patients., PMID:28344074
Dynamic mislocalizations of nuclear pore complex proteins after focal cerebral ischemia in rat., PMID:28029704
Tracking the Antibody Immunome in Type 1 Diabetes Using Protein Arrays., PMID:27690455
Transcription factor Sp1 prevents TRF2(ΔBΔM)-induced premature senescence in human diploid fibroblasts., PMID:26906205
NUP50 is necessary for the survival of primordial germ cells in mouse embryos., PMID:26515778
Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS., PMID:26304019
Three cardiovirus Leader proteins equivalently inhibit four different nucleocytoplasmic trafficking pathways., PMID:26115166
Analysis of the initiation of nuclear pore assembly by ectopically targeting nucleoporins to chromatin., PMID:25602437
Structural characterization of altered nucleoporin Nup153 expression in human cells by thin-section electron microscopy., PMID:25485891
Nup50 is required for cell differentiation and exhibits transcription-dependent dynamics., PMID:24943837
Identification of genetic modifiers of TDP-43 neurotoxicity in Drosophila., PMID:23468938
Sequence-dependent structural dynamics of primate adenosine-to-inosine editing substrates., PMID:23193088
The Nup153-Nup50 protein interface and its role in nuclear import., PMID:23007389
Nucleoporin Nup50 stabilizes closed conformation of armadillo repeat 10 in importin α5., PMID:22130666
Coordinating postmitotic nuclear pore complex assembly with abscission timing., PMID:21941107
Defects in nuclear pore assembly lead to activation of an Aurora B-mediated abscission checkpoint., PMID:21098116
Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm., PMID:20144760
NPP-16/Nup50 function and CDK-1 inactivation are associated with anoxia-induced prophase arrest in Caenorhabditis elegans., PMID:20053678
Two isoforms of Npap60 (Nup50) differentially regulate nuclear protein import., PMID:20016008
Substrate screening identifies a novel target sequence for the proteasomal activity regulated by ionizing radiation., PMID:19957288
Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport., PMID:19767751
Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells., PMID:19167330
Interaction of the melanocortin 2 receptor with nucleoporin 50: evidence for a novel pathway between a G-protein-coupled receptor and the nucleus., PMID:17625072
Structural basis for the nuclear protein import cycle., PMID:17052178
For research use only. Not for human or drug use.
