Catalog No.
YHJ77901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Leu216
Predicted molecular weight
26.26 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UIS9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CXXC3, PCM1, CXXC-type zinc finger protein 3, Protein containing methyl-CpG-binding domain 1, Methyl-CpG-binding domain protein 1, MBD1, Methyl-CpG-binding protein MBD1
The Kinesin-14 tail: Dual microtubule binding domains drive spindle morphogenesis through tight microtubule cross-linking and robust sliding., PMID:40327372
The Kinesin-14 Tail: Dual microtubule binding domains drive spindle morphogenesis through tight microtubule cross-linking and robust sliding., PMID:40060502
Tuning the Sensitivity of MoS2 Nanopores: From Labeling to Labeling-Free Detection of DNA Methylation., PMID:39555656
Mechanistic model for epigenetic maintenance by methyl-CpG-binding domain proteins., PMID:39386650
Association between the copy number variations of Methyl-CpG binding domain family and schizophrenia., PMID:39127413
DNA hypomethylation in wood frog liver under anoxia and dehydration stresses., PMID:38969165
Diverse roles of the metal binding domains and transport mechanism of copper transporting P-type ATPases., PMID:38538615
Exposure to the extremely low-frequency electromagnetic field induces changes in the epigenetic regulation of gene expression in the endometrium., PMID:38262222
MBD2 couples DNA methylation to transposable element silencing during male gametogenesis., PMID:38225352
Light-Activatable MBD-Readers of 5-Methylcytosine Reveal Domain-Dependent Chromatin Association Kinetics In Vivo., PMID:38164822
MBD1 protects replication fork stability by recruiting PARP1 and controlling transcription-replication conflicts., PMID:37949945
LncRNA SNHG20 silencing inhibits hepatocellular carcinoma progression by sponging miR-5095 from MBD1., PMID:37434830
Integrative analyses of biomarkers and pathways for diabetic nephropathy., PMID:37113991
Histone H3K9 methyltransferase SETDB1 overexpression correlates with pediatric high-grade gliomas progression and prognosis., PMID:36811655
Short-term in vivo testing to discriminate genotoxic carcinogens from non-genotoxic carcinogens and non-carcinogens using next-generation RNA sequencing, DNA microarray, and qPCR., PMID:36755350
Forward genetic screen of homeostatic antibody levels in the Collaborative Cross identifies MBD1 as a novel regulator of B cell homeostasis., PMID:36574452
Trichostatin A-Mediated Epigenetic Modulation Predominantly Triggers Transcriptomic Alterations in the Ex Vivo Expanded Equine Chondrocytes., PMID:36361948
Copper binding leads to increased dynamics in the regulatory N-terminal domain of full-length human copper transporter ATP7B., PMID:36070320
Endogenous Retroviral Sequences Behave as Putative Enhancers Controlling Gene Expression through HP1-Regulated Long-Range Chromatin Interactions., PMID:35954237
MBD1/HDAC3-miR-5701-FGFR2 axis promotes the development of gastric cancer., PMID:35876658
Thymoquinone upregulates IL17RD in controlling the growth and metastasis of triple negative breast cancer cells in vitro., PMID:35761256
Optochemical Control of TET Dioxygenases Enables Kinetic Insights into the Domain-Dependent Interplay of TET1 and MBD1 while Oxidizing and Reading 5-Methylcytosine., PMID:35709470
Association between forkhead box P3 expression level and gender of Iranian juvenile idiopathic arthritis patients., PMID:35645413
In silico prediction and interaction of resveratrol on methyl-CpG binding proteins by molecular docking and MD simulations study., PMID:35425086
Candida albicans Modulates Murine and Human Beta Defensin-1 during Vaginitis., PMID:35049960
High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases., PMID:34718755
Tissue-specific DNase I footprint analysis confirms the association of GATAD2B Q470* variant with intellectual disability., PMID:34470925
At sixes and sevens: cryptic domain in the metal binding chain of the human copper transporter ATP7A., PMID:34461106
The Updating of Biological Functions of Methyltransferase SETDB1 and Its Relevance in Lung Cancer and Mesothelioma., PMID:34299035
Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk., PMID:34103526
CD44 alternative splicing senses intragenic DNA methylation in tumors via direct and indirect mechanisms., PMID:34086943
A domesticated Harbinger transposase forms a complex with HDA6 and promotes histone H3 deacetylation at genes but not TEs in Arabidopsis., PMID:33960113
RET Protein Expression in Colorectal Cancer; An Immunohistochemical Assessment., PMID:33906292
Epigenetic effects of insecticides on early differentiation of mouse embryonic stem cells., PMID:33865946
Expression of DnMTs and MBDs in AlCl3-Induced Neurotoxicity Mouse Model., PMID:33174148
A Novel Immunocompetent Mouse Model for Testing Antifungal Drugs Against Invasive Candida albicans Infection., PMID:33007818
An EPR Study on the Interaction between the Cu(I) Metal Binding Domains of ATP7B and the Atox1 Metallochaperone., PMID:32748830
Melatonin-induced suppression of DNA methylation promotes odontogenic differentiation in human dental pulp cells., PMID:32718272
Adolescent chronic intermittent toluene inhalation dynamically regulates the transcriptome and neuronal methylome within the rat medial prefrontal cortex., PMID:32638524
NR2F2-AS1 accelerates cell proliferation through regulating miR-4429/MBD1 axis in cervical cancer., PMID:32469064
Complete Profiling of Methyl-CpG-Binding Domains for Combinations of Cytosine Modifications at CpG Dinucleotides Reveals Differential Read-out in Normal and Rett-Associated States., PMID:32132616
Assessment of Immuno-Histochemical Expression of MBD1 in Colorectal Adenocarcinoma and Its Correlations with Prognostic Factors., PMID:32082520
LyP-1-fMWNTs enhanced targeted delivery of MBD1siRNA to pancreatic cancer cells., PMID:31968405
Loss of the Epigenetic Mark 5-hmC in Psoriasis: Implications for Epidermal Stem Cell Dysregulation., PMID:31837302
Expression of key genes involved in DNA methylation during in vitro differentiation of porcine mesenchymal stem cells (MSCs) into adipocytes., PMID:31791576
Early Postnatal Treatment with Valproate Induces Gad1 Promoter Remodeling in the Brain and Reduces Apnea Episodes in Mecp2-Null Mice., PMID:31635390
Retraction: Regulation of MBD1-mediated transcriptional repression by SUMO and PIAS proteins., PMID:31612521
MBD1 promotes the malignant behavior of gallbladder cancer cells and induces chemotherapeutic resistance to gemcitabine., PMID:31516389
Long noncoding RNA MEG3 silencing protects against hypoxia-induced pheochromocytoma-12 cell injury through inhibition of TIMP2 promoter methylation., PMID:31392726
Copper relay path through the N-terminus of Wilson disease protein, ATP7B., PMID:31321400
For research use only. Not for human or drug use.
